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Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levels

Basic Information

ID: ALA2091979

Type: Binding

Description: Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levels

Format: BAO_0000219

Organism: Rattus norvegicus

Cell type: HEK293

Target:  Transient receptor potential cation channel subfamily M member 8(ALA5011)

Document:  ALA2086321

Inhibition of rat TRPM8 expressed in HEK293 cells assessed as reduction in 20 uM menthol-stimulated increase in intracellular Ca2+ levels: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
150.222.822.82
299.374.744.74
268.364.654.65
310.445.645.64
330.436.006.00
284.364.354.35
344.455.935.93
310.445.645.64
330.436.006.00
288.774.994.99
284.364.354.35
309.455.675.67
321.345.395.39
329.446.046.04
287.795.025.02
283.374.384.38
281.404.094.09
426.566.156.15
309.455.675.67
329.446.046.04
283.374.384.38
343.475.975.97
393.274.904.90
351.536.646.64
325.456.036.03
337.345.755.75
345.446.406.40
345.446.406.40
299.374.744.74
325.456.036.03
345.446.406.40
324.476.066.06
344.466.436.43
298.394.774.77
185.702.702.70