Inhibition of TNFalpha release in rat LPS-induced endotoxemia model dosed orally 1 hr prior to LPS challenge and measured 1.5 hrs post LPS challenge

Basic Information

ID: ALA2092522

Type: Functional

Description: Inhibition of TNFalpha release in rat LPS-induced endotoxemia model dosed orally 1 hr prior to LPS challenge and measured 1.5 hrs post LPS challenge

Format: BAO_0000218

Organism: Rattus norvegicus

Target: Rattus norvegicus(ALA376)

Document: ALA2086331

Inhibition of TNFalpha release in rat LPS-induced endotoxemia model dosed orally 1 hr prior to LPS challenge and measured 1.5 hrs post LPS challenge: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2092522

ED50

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
348.45	3.89	3.89
402.42	4.31	4.31

Parent Molecular Weight

ALogP

Polar Surface Area

348.45

3.89

402.42

4.31

Inhibition of TNFalpha release in rat LPS-induced endotoxemia model dosed orally 1 hr prior to LPS challenge and measured 1.5 hrs post LPS challenge

Basic Information

Activity Charts

Compound Summary