Basic Information
ID: ALA2098499
Type: ADME
Description: GSK_TB: GSK in-house kinetic solubility assay. DMSO stock solution diluted to 100 ml with pH 7.4 phosphate buffered saline.
Format: BAO_0000019
Target: ADMET(ALA612558)
Document: ALA2095176
GSK_TB: GSK in-house kinetic solubility assay. DMSO stock solution diluted to 100 ml with pH 7.4 phosphate buffered saline.: 22
Activity Charts
Bioactivity
Activity Types for Assay ALA2098499
Solubility
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.28 | 2.42 | 2.42 |
| 358.83 | 5.39 | 5.39 |
| 435.33 | 4.67 | 4.67 |
| 428.38 | 2.58 | 2.58 |
| 392.30 | 2.00 | 2.00 |
| 400.32 | 1.84 | 1.84 |
| 291.40 | 4.01 | 4.01 |
| 380.88 | 4.55 | 4.55 |
| 456.39 | 2.43 | 2.43 |
| 386.29 | 1.59 | 1.59 |
| 336.38 | 3.91 | 3.91 |
| 416.55 | 5.10 | 5.10 |
| 466.93 | -0.91 | -0.91 |
| 307.33 | 4.01 | 4.01 |
| 301.40 | 3.83 | 3.83 |
| 357.44 | 4.64 | 4.64 |
| 300.25 | 2.24 | 2.24 |
| 325.39 | 3.61 | 3.61 |
| 240.31 | 2.76 | 2.76 |
| 222.56 | 1.80 | 1.80 |
| 283.76 | 4.20 | 4.20 |
| 314.79 | 3.53 | 3.53 |
| 211.31 | 2.45 | 2.45 |
| 367.71 | 4.66 | 4.66 |
| 313.36 | 3.53 | 3.53 |
| 349.83 | 4.10 | 4.10 |
| 526.52 | 3.48 | 3.48 |
| 450.57 | 3.49 | 3.49 |
| 256.23 | 3.15 | 3.15 |
| 370.47 | 2.92 | 2.92 |
| 400.32 | 1.89 | 1.89 |
| 315.38 | 3.45 | 3.45 |
| 431.46 | 3.60 | 3.60 |
| 392.94 | 4.14 | 4.14 |
| 540.55 | 3.78 | 3.78 |
| 380.51 | 4.97 | 4.97 |
| 411.38 | 5.08 | 5.08 |
| 219.68 | 3.06 | 3.06 |
| 548.37 | 4.14 | 4.14 |
| 299.76 | 3.23 | 3.23 |
| 345.44 | 4.33 | 4.33 |
| 383.84 | 5.15 | 5.15 |
| 435.60 | 4.03 | 4.03 |
| 373.43 | 3.84 | 3.84 |
| 732.57 | 5.27 | 5.27 |
| 307.40 | 4.19 | 4.19 |
| 397.36 | 3.93 | 3.93 |
| 364.37 | 3.10 | 3.10 |
| 391.39 | 4.38 | 4.38 |
| 253.23 | 3.43 | 3.43 |
| 491.51 | 3.46 | 3.46 |
| 259.31 | -0.57 | -0.57 |
| 385.26 | 4.00 | 4.00 |
| 441.52 | 5.71 | 5.71 |
| 324.43 | 4.15 | 4.15 |
| 412.33 | 3.68 | 3.68 |
| 435.55 | 3.56 | 3.56 |
| 351.84 | 4.43 | 4.43 |
| 301.35 | 4.05 | 4.05 |
| 377.47 | 4.56 | 4.56 |
| 402.20 | 4.90 | 4.90 |
| 339.34 | 3.65 | 3.65 |
| 446.50 | 4.68 | 4.68 |
| 377.32 | 3.32 | 3.32 |
| 383.48 | 3.11 | 3.11 |
| 335.36 | 3.79 | 3.79 |
| 410.47 | 4.79 | 4.79 |
| 269.30 | 2.47 | 2.47 |
| 267.35 | 2.12 | 2.12 |
| 467.57 | 4.00 | 4.00 |
| 410.50 | 3.54 | 3.54 |
| 332.45 | 4.43 | 4.43 |
| 349.41 | 3.10 | 3.10 |
| 494.64 | 4.56 | 4.56 |
| 435.55 | 3.56 | 3.56 |
| 245.33 | 2.34 | 2.34 |
| 352.46 | 4.48 | 4.48 |
| 347.40 | 3.64 | 3.64 |
| 385.82 | 5.42 | 5.42 |
| 388.18 | 4.59 | 4.59 |
| 231.32 | 2.95 | 2.95 |
| 363.30 | 3.01 | 3.01 |
| 434.49 | 5.10 | 5.10 |
| 465.55 | 3.93 | 3.93 |
| 337.30 | 3.49 | 3.49 |
| 339.42 | 3.97 | 3.97 |
| 441.16 | 2.58 | 2.58 |
| 475.62 | 4.54 | 4.54 |
| 427.65 | 4.69 | 4.69 |
| 382.40 | 2.93 | 2.93 |
| 359.48 | 3.99 | 3.99 |
| 320.44 | 3.08 | 3.08 |
| 430.46 | 3.71 | 3.71 |
| 423.33 | 4.48 | 4.48 |
| 317.45 | 4.02 | 4.02 |
| 433.44 | 4.74 | 4.74 |
| 327.43 | 4.18 | 4.18 |
| 323.27 | 3.18 | 3.18 |
| 344.78 | 3.70 | 3.70 |
| 331.42 | 2.96 | 2.96 |