Assay Report Card

Basic Information

ID: ALA2114011

Type: Functional

Description: OSM: Mice are infected intravenously with parasitized red blood cells on day 0 (2 x 107 parasitized erythrocytes per ml). Experimental mice are generally treated at 4, 24, 48, and 72 hours post-infection with an oral dose of the compound (50 mg/kg, 4-day test by Peters) and are compared to an infected control group for reduction in parasitaemia on day 4 (96 hours post-infection) as a percentage.

Organism: Mus musculus

Strain: Swiss

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
476.513.833.83
290.291.881.88
373.484.994.99