Basic Information
ID: ALA2114737
Type: Functional
Description: PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits of SUMO1-mediated protein-protein interactions using a fluorescence polarization assay. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114737
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.91 | 6.61 | 6.61 |
| 663.08 | 7.12 | 7.12 |
| 562.67 | 7.50 | 7.50 |
| 268.22 | 3.10 | 3.10 |
| 395.42 | -0.17 | -0.17 |
| 418.28 | 3.92 | 3.92 |
| 432.91 | 3.93 | 3.93 |
| 337.81 | 4.43 | 4.43 |
| 386.31 | 2.32 | 2.32 |
| 287.32 | 3.57 | 3.57 |
| 345.38 | 3.54 | 3.54 |
| 460.63 | 6.24 | 6.24 |
| 436.99 | 5.97 | 5.97 |
| 453.46 | -0.54 | -0.54 |
| 348.31 | 2.69 | 2.69 |
| 538.46 | 5.13 | 5.13 |
| 282.30 | 3.48 | 3.48 |
| 475.39 | 1.62 | 1.62 |
| 350.38 | 3.30 | 3.30 |
| 337.43 | 1.19 | 1.19 |
| 385.38 | 3.96 | 3.96 |
| 459.29 | 4.96 | 4.96 |
| 687.71 | 10.29 | 10.29 |
| 315.35 | 3.54 | 3.54 |
| 422.49 | 2.28 | 2.28 |
| 377.42 | 1.20 | 1.20 |
| 284.28 | 1.56 | 1.56 |
| 566.61 | 3.76 | 3.76 |
| 487.51 | 5.41 | 5.41 |
| 405.53 | 4.02 | 4.02 |
| 354.44 | 3.12 | 3.12 |
| 296.28 | 2.80 | 2.80 |
| 391.42 | 4.45 | 4.45 |
| 456.53 | 3.94 | 3.94 |
| 441.28 | 5.60 | 5.60 |
| 288.30 | 4.32 | 4.32 |
| 472.50 | 3.33 | 3.33 |
| 435.02 | 6.80 | 6.80 |
| 297.34 | 2.46 | 2.46 |
| 523.50 | 4.84 | 4.84 |
| 400.53 | 5.23 | 5.23 |
| 398.42 | 2.74 | 2.74 |
| 436.90 | 4.15 | 4.15 |
| 243.31 | 2.84 | 2.84 |
| 469.52 | 5.27 | 5.27 |
| 395.44 | 2.68 | 2.68 |
| 410.47 | 2.12 | 2.12 |
| 484.51 | 6.25 | 6.25 |
| 376.33 | ||
| 490.59 | 5.01 | 5.01 |
| 438.47 | 2.47 | 2.47 |
| 536.59 | 3.70 | 3.70 |
| 496.57 | 3.91 | 3.91 |
| 246.40 | 2.68 | 2.68 |
| 862.75 | -1.10 | -1.10 |
| 318.79 | 4.01 | 4.01 |
| 384.44 | 3.02 | 3.02 |
| 410.47 | 2.12 | 2.12 |
| 443.46 | 4.52 | 4.52 |
| 363.33 | 3.39 | 3.39 |
| 396.45 | 1.73 | 1.73 |
| 487.51 | 5.41 | 5.41 |
| 521.49 | 6.19 | 6.19 |
| 476.55 | 5.02 | 5.02 |
| 468.56 | 5.64 | 5.64 |
| 401.44 | 2.23 | 2.23 |
| 323.33 | 2.43 | 2.43 |
| 466.50 | 4.90 | 4.90 |
| 159.19 | 1.40 | 1.40 |
| 252.66 | 2.15 | 2.15 |
| 480.49 | 1.10 | 1.10 |
| 430.60 | 6.24 | 6.24 |
| 321.34 | 3.04 | 3.04 |
| 476.50 | 6.28 | 6.28 |
| 546.67 | 5.72 | 5.72 |
| 405.27 | 3.56 | 3.56 |
| 412.31 | 3.65 | 3.65 |
| 264.31 | 2.26 | 2.26 |
| 448.88 | 4.04 | 4.04 |
| 428.47 | 2.30 | 2.30 |
| 493.50 | 3.54 | 3.54 |
| 437.30 | 3.30 | 3.30 |
| 403.46 | 1.86 | 1.86 |
| 536.50 | 2.59 | 2.59 |
| 333.39 | 3.74 | 3.74 |
| 425.47 | 2.83 | 2.83 |
| 474.50 | 1.39 | 1.39 |
| 489.58 | 5.31 | 5.31 |
| 314.30 | 2.47 | 2.47 |
| 498.56 | 1.55 | 1.55 |
| 324.29 | 1.61 | 1.61 |
| 495.00 | 5.97 | 5.97 |
| 390.79 | 4.41 | 4.41 |
| 359.40 | 3.86 | 3.86 |
| 558.53 | 7.49 | 7.49 |
| 278.31 | 2.56 | 2.56 |
| 512.97 | 2.92 | 2.92 |
| 366.37 | 3.42 | 3.42 |
| 407.81 | 3.93 | 3.93 |
| 436.99 | 5.97 | 5.97 |
| 278.31 | 3.39 | 3.39 |
| 245.27 | 1.15 | 1.15 |
| 420.83 | 4.20 | 4.20 |
| 500.51 | 3.99 | 3.99 |
| 347.42 | 3.50 | 3.50 |
| 353.38 | 2.94 | 2.94 |
| 328.29 | 0.44 | 0.44 |
| 412.31 | 3.65 | 3.65 |
| 481.51 | 7.61 | 7.61 |
| 523.46 | 4.23 | 4.23 |
| 360.33 | 3.40 | 3.40 |
| 415.42 | 3.63 | 3.63 |
| 356.39 | 4.22 | 4.22 |
| 498.54 | 3.51 | 3.51 |
| 486.96 | 3.54 | 3.54 |
| 427.47 | 5.55 | 5.55 |
| 314.32 | 2.21 | 2.21 |
| 315.72 | 3.35 | 3.35 |
| 263.30 | 2.42 | 2.42 |
| 382.89 | 2.95 | 2.95 |
| 258.23 | 2.42 | 2.42 |
| 384.39 | 3.94 | 3.94 |
| 438.35 | 3.42 | 3.42 |
| 525.97 | 6.24 | 6.24 |
| 376.41 | 5.15 | 5.15 |
| 430.84 | 4.39 | 4.39 |
| 489.94 | 4.59 | 4.59 |
| 469.52 | 3.45 | 3.45 |
| 307.29 | 1.85 | 1.85 |
| 382.46 | 3.60 | 3.60 |
| 438.53 | 4.40 | 4.40 |
| 439.59 | 5.29 | 5.29 |
| 359.34 | 3.87 | 3.87 |
| 332.32 | 3.16 | 3.16 |
| 484.49 | 3.94 | 3.94 |
| 407.48 | 5.28 | 5.28 |
| 421.46 | 1.62 | 1.62 |
| 416.46 | 2.41 | 2.41 |
| 526.53 | 4.11 | 4.11 |
| 287.32 | 2.40 | 2.40 |
| 314.35 | 3.62 | 3.62 |
| 486.51 | 2.24 | 2.24 |
| 360.31 | 2.71 | 2.71 |
| 393.40 | 1.98 | 1.98 |
| 376.32 | 4.21 | 4.21 |
| 417.26 | 3.31 | 3.31 |
| 351.43 | 3.94 | 3.94 |
| 358.85 | 4.53 | 4.53 |
| 496.95 | 2.88 | 2.88 |
| 396.45 | 1.73 | 1.73 |
| 486.53 | 4.26 | 4.26 |
| 393.36 | 1.91 | 1.91 |
| 507.49 | 8.30 | 8.30 |
| 426.84 | 4.92 | 4.92 |
| 494.91 | 1.74 | 1.74 |
| 381.18 | 2.77 | 2.77 |
| 536.63 | 4.37 | 4.37 |
| 385.44 | 4.16 | 4.16 |
| 372.40 | 3.34 | 3.34 |
| 363.37 | 4.66 | 4.66 |
| 497.52 | 2.80 | 2.80 |
| 432.57 | 3.71 | 3.71 |
| 261.35 | 3.48 | 3.48 |
| 542.59 | 3.91 | 3.91 |
| 432.72 | 3.91 | 3.91 |
| 315.38 | 4.06 | 4.06 |
| 428.48 | 3.37 | 3.37 |
| 476.60 | 5.29 | 5.29 |
| 435.02 | 6.66 | 6.66 |
| 449.05 | 7.19 | 7.19 |
| 386.83 | 4.66 | 4.66 |
| 462.89 | 5.17 | 5.17 |
| 385.35 | 2.55 | 2.55 |
| 369.43 | 4.51 | 4.51 |
| 455.54 | 3.15 | 3.15 |
| 421.45 | 3.25 | 3.25 |
| 405.82 | 3.94 | 3.94 |
| 373.37 | 3.27 | 3.27 |
| 451.28 | 5.81 | 5.81 |
| 548.61 | 7.28 | 7.28 |
| 395.38 | 1.17 | 1.17 |
| 489.58 | 4.58 | 4.58 |
| 257.29 | 2.43 | 2.43 |
| 491.74 | 4.12 | 4.12 |
| 260.23 | 2.09 | 2.09 |
| 307.35 | 2.01 | 2.01 |
| 381.48 | 4.33 | 4.33 |
| 409.42 | 4.51 | 4.51 |
| 341.82 | 4.17 | 4.17 |
| 288.22 | -0.04 | -0.04 |
| 446.91 | 4.55 | 4.55 |
| 282.34 | 3.26 | 3.26 |
| 237.61 | 2.16 | 2.16 |
| 352.31 | 3.52 | 3.52 |
| 398.40 | 3.56 | 3.56 |
| 526.60 | 2.78 | 2.78 |
| 603.23 | ||
| 388.34 | 1.89 | 1.89 |
| 253.28 | 3.19 | 3.19 |
| 397.48 | 4.03 | 4.03 |
| 395.41 | 4.01 | 4.01 |
| 500.49 | 3.56 | 3.56 |
| 695.05 | ||
| 391.43 | 3.91 | 3.91 |
| 338.39 | 3.42 | 3.42 |
| 478.46 | 1.22 | 1.22 |
| 265.35 | 2.49 | 2.49 |
| 421.43 | 2.39 | 2.39 |
| 374.30 | 3.02 | 3.02 |
| 324.29 | 3.03 | 3.03 |
| 372.06 | 4.88 | 4.88 |
| 379.12 | 4.38 | 4.38 |
| 376.32 | 4.21 | 4.21 |
| 420.99 | 6.27 | 6.27 |
| 406.19 | 2.81 | 2.81 |
| 524.62 | 2.98 | 2.98 |
| 288.69 | 3.48 | 3.48 |
| 438.96 | 3.11 | 3.11 |
| 420.52 | 2.81 | 2.81 |
| 527.00 | 3.30 | 3.30 |
| 803.32 | 0.24 | 0.24 |
| 255.23 | 2.58 | 2.58 |
| 308.36 | 2.66 | 2.66 |
| 539.71 | 5.59 | 5.59 |
| 370.36 | 2.20 | 2.20 |
| 194.19 | 0.15 | 0.15 |
| 459.53 | 6.38 | 6.38 |
| 318.79 | 4.01 | 4.01 |
| 322.46 | 3.89 | 3.89 |
| 803.32 | 0.24 | 0.24 |
| 968.85 | 13.59 | 13.59 |
| 417.46 | 2.56 | 2.56 |
| 581.32 | 6.95 | 6.95 |
| 315.35 | 3.54 | 3.54 |
| 306.75 | 4.14 | 4.14 |
| 384.39 | 3.94 | 3.94 |
| 502.58 | 6.69 | 6.69 |
| 408.54 | 6.12 | 6.12 |
| 239.25 | 1.37 | 1.37 |
| 315.35 | 3.54 | 3.54 |
| 416.48 | 4.53 | 4.53 |
| 423.49 | 3.21 | 3.21 |
| 593.22 | 7.93 | 7.93 |
| 312.24 | 0.24 | 0.24 |
| 462.33 | 3.48 | 3.48 |
| 433.54 | 3.59 | 3.59 |
| 299.44 | 2.00 | 2.00 |
| 386.84 | 3.59 | 3.59 |
| 367.53 | 3.39 | 3.39 |
| 646.13 | 6.12 | 6.12 |
| 168.15 | 0.66 | 0.66 |
| 411.41 | 2.81 | 2.81 |
| 471.56 | 3.85 | 3.85 |
| 209.16 | 0.46 | 0.46 |
| 246.22 | 1.45 | 1.45 |
| 474.04 | 5.21 | 5.21 |
| 185.19 | 1.99 | 1.99 |
| 373.76 | 3.30 | 3.30 |
| 431.34 | 4.33 | 4.33 |
| 504.55 | 5.14 | 5.14 |
| 351.41 | 4.02 | 4.02 |
| 403.41 | 4.00 | 4.00 |
| 361.74 | 2.78 | 2.78 |
| 422.85 | 4.07 | 4.07 |
| 403.44 | 3.43 | 3.43 |
| 433.42 | 4.07 | 4.07 |
| 414.87 | 3.30 | 3.30 |
| 388.40 | 3.42 | 3.42 |
| 438.87 | 3.53 | 3.53 |
| 493.50 | 5.19 | 5.19 |
| 380.86 | 4.16 | 4.16 |
| 392.42 | 3.97 | 3.97 |
| 549.36 | 4.31 | 4.31 |
| 594.63 | 3.94 | 3.94 |
| 351.71 | 2.70 | 2.70 |
| 286.36 | 3.55 | 3.55 |
| 416.46 | 4.03 | 4.03 |
| 460.37 | 3.54 | 3.54 |
| 398.42 | 4.65 | 4.65 |
| 839.97 | 2.25 | 2.25 |
| 580.56 | 4.02 | 4.02 |
| 408.41 | 1.60 | 1.60 |
| 483.89 | 5.44 | 5.44 |
| 378.82 | 3.75 | 3.75 |
| 310.74 | 4.08 | 4.08 |
| 439.59 | 4.55 | 4.55 |
| 355.83 | 5.02 | 5.02 |
| 361.41 | 3.83 | 3.83 |
| 315.33 | 3.74 | 3.74 |
| 464.43 | 3.09 | 3.09 |
| 624.86 | 4.67 | 4.67 |
| 240.26 | 1.28 | 1.28 |