ID: ALA2114744
Type: Functional
Description: PubChem BioAssay. HTS Assay for Allosteric Antagonists of the Human D2 Dopamine Receptor: Hit Validation in HTRF. (Class of assay: confirmatory)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2114744
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
160.22 | 1.67 | 1.67 |
290.32 | 1.26 | 1.26 |
169.18 | 0.09 | 0.09 |
190.25 | 1.68 | 1.68 |
263.38 | 3.83 | 3.83 |
399.97 | 5.97 | 5.97 |
219.33 | 2.98 | 2.98 |
219.33 | 2.98 | 2.98 |
395.43 | 2.42 | 2.42 |
267.33 | 2.85 | 2.85 |
444.49 | -0.14 | -0.14 |
336.33 | -0.13 | -0.13 |
153.18 | 0.60 | 0.60 |
287.79 | 3.67 | 3.67 |
351.41 | 1.56 | 1.56 |
654.61 | 3.19 | 3.19 |
163.17 | -2.97 | -2.97 |
137.18 | 0.89 | 0.89 |
332.34 | 3.43 | 3.43 |
211.26 | 1.08 | 1.08 |
371.25 | ||
314.50 | 4.27 | 4.27 |
82.11 | 0.42 | 0.42 |
242.27 | 2.75 | 2.75 |
284.43 | 4.24 | 4.24 |
237.34 | 2.76 | 2.76 |
305.76 | 2.73 | 2.73 |
190.25 | 1.76 | 1.76 |
163.20 | -0.49 | -0.49 |
212.30 | 2.25 | 2.25 |
283.33 | 2.56 | 2.56 |
246.31 | 4.49 | 4.49 |
123.11 | -0.42 | -0.42 |
278.31 | 0.19 | 0.19 |
277.41 | 3.04 | 3.04 |
459.41 | 5.17 | 5.17 |
265.37 | 3.51 | 3.51 |
183.21 | 0.35 | 0.35 |
320.43 | 5.17 | 5.17 |
202.35 | -0.36 | -0.36 |
345.40 | 2.51 | 2.51 |
247.38 | 3.37 | 3.37 |
414.59 | 5.04 | 5.04 |
179.22 | 0.91 | 0.91 |
158.11 | -0.54 | -0.54 |
187.17 | 0.23 | 0.23 |
167.21 | 0.86 | 0.86 |
311.38 | 3.34 | 3.34 |
247.32 | 2.39 | 2.39 |
454.45 | 0.27 | 0.27 |
255.32 | 2.38 | 2.38 |
374.28 | 4.04 | 4.04 |
329.83 | 3.93 | 3.93 |
295.38 | 3.27 | 3.27 |
247.38 | 3.37 | 3.37 |
275.09 | 1.27 | 1.27 |
335.45 | 4.31 | 4.31 |
327.81 | 3.77 | 3.77 |
329.44 | 3.26 | 3.26 |
218.26 | 0.54 | 0.54 |
349.39 | 0.18 | 0.18 |
153.18 | 0.38 | 0.38 |
247.38 | 3.37 | 3.37 |
301.39 | 2.96 | 2.96 |
255.36 | 3.72 | 3.72 |
249.31 | 1.94 | 1.94 |
197.19 | 0.05 | 0.05 |
353.47 | 1.94 | 1.94 |
271.32 | 2.41 | 2.41 |
264.33 | 3.25 | 3.25 |
195.26 | 3.56 | 3.56 |
161.16 | -0.35 | -0.35 |
136.20 | 0.69 | 0.69 |
166.24 | 1.98 | 1.98 |
249.32 | 2.47 | 2.47 |
293.37 | 3.41 | 3.41 |
329.21 | -0.82 | -0.82 |
248.29 | 0.62 | 0.62 |
104.18 | 0.63 | 0.63 |
327.34 | 3.05 | 3.05 |
309.45 | 4.20 | 4.20 |
331.76 | 3.21 | 3.21 |
359.73 | 2.43 | 2.43 |
499.53 | -0.16 | -0.16 |
375.47 | 4.20 | 4.20 |
195.69 | 2.37 | 2.37 |
135.17 | 0.55 | 0.55 |
355.31 | 4.01 | 4.01 |
167.21 | 0.65 | 0.65 |
246.36 | 1.65 | 1.65 |
91.07 | -1.04 | -1.04 |
116.12 | -1.06 | -1.06 |
356.18 | 5.18 | 5.18 |
289.76 | 3.03 | 3.03 |
355.99 | 2.78 | 2.78 |
361.46 | 3.23 | 3.23 |
318.50 | 4.60 | 4.60 |
169.18 | 0.09 | 0.09 |
476.79 | 4.68 | 4.68 |
295.38 | 3.63 | 3.63 |
247.25 | 1.58 | 1.58 |
204.30 | 2.15 | 2.15 |
216.32 | 4.18 | 4.18 |
219.33 | 2.00 | 2.00 |
417.63 | 6.79 | 6.79 |
360.45 | 1.99 | 1.99 |
102.09 | -1.62 | -1.62 |
360.37 | 2.57 | 2.57 |
464.86 | 0.26 | 0.26 |
242.03 | 2.23 | 2.23 |
223.23 | 0.34 | 0.34 |
583.69 | 2.08 | 2.08 |
183.21 | 0.35 | 0.35 |
317.82 | 3.68 | 3.68 |
611.74 | 2.72 | 2.72 |
153.16 | -1.38 | -1.38 |
211.26 | 1.13 | 1.13 |
836.39 | -2.45 | -2.45 |
269.34 | 2.72 | 2.72 |
195.22 | 0.74 | 0.74 |
339.44 | 1.92 | 1.92 |
168.15 | 1.22 | 1.22 |
339.44 | 3.25 | 3.25 |
429.60 | 5.41 | 5.41 |
325.45 | 3.14 | 3.14 |
522.61 | 2.97 | 2.97 |
211.22 | 0.14 | 0.14 |
195.22 | 0.74 | 0.74 |
410.51 | 1.52 | 1.52 |
541.63 | -0.98 | -0.98 |
230.31 | 2.68 | 2.68 |
226.23 | -0.05 | -0.05 |
473.30 | -1.02 | -1.02 |
586.68 | -1.44 | -1.44 |
390.57 | 3.68 | 3.68 |
424.10 | -0.76 | -0.76 |
261.35 | 2.74 | 2.74 |
231.34 | 2.91 | 2.91 |
471.82 | 1.99 | 1.99 |
408.11 | -0.05 | -0.05 |
247.34 | 2.17 | 2.17 |
337.81 | 4.79 | 4.79 |
616.84 | 5.75 | 5.75 |