Basic Information
ID: ALA2114747
Type: Functional
Description: PubChem BioAssay. InCell qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in WT MEF Cells: Hit Validation. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114747
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 585.70 | 2.54 | 2.54 |
| 438.96 | 4.60 | 4.60 |
| 430.60 | 5.28 | 5.28 |
| 488.02 | 3.31 | 3.31 |
| 408.55 | 3.16 | 3.16 |
| 405.50 | 4.80 | 4.80 |
| 426.56 | 4.97 | 4.97 |
| 588.48 | 6.89 | 6.89 |
| 421.54 | 4.20 | 4.20 |
| 323.37 | 4.72 | 4.72 |
| 463.41 | 4.15 | 4.15 |
| 396.54 | 3.01 | 3.01 |
| 408.55 | 3.16 | 3.16 |
| 367.49 | 3.86 | 3.86 |
| 310.78 | 2.22 | 2.22 |
| 443.29 | 5.15 | 5.15 |
| 338.84 | 5.44 | 5.44 |
| 280.33 | 1.68 | 1.68 |
| 414.29 | 4.96 | 4.96 |
| 381.46 | 3.30 | 3.30 |
| 498.65 | 5.89 | 5.89 |
| 425.46 | 4.97 | 4.97 |
| 388.47 | 5.29 | 5.29 |
| 457.46 | 3.73 | 3.73 |
| 416.39 | 4.33 | 4.33 |
| 416.64 | 4.31 | 4.31 |
| 437.93 | 3.08 | 3.08 |
| 404.55 | 4.94 | 4.94 |
| 404.52 | 4.43 | 4.43 |
| 454.50 | 2.83 | 2.83 |
| 469.95 | 5.74 | 5.74 |
| 447.60 | 4.88 | 4.88 |
| 410.32 | 5.17 | 5.17 |
| 404.40 | 5.09 | 5.09 |
| 440.63 | 6.51 | 6.51 |
| 636.24 | 6.33 | 6.33 |
| 406.36 | 5.34 | 5.34 |
| 477.30 | 4.34 | 4.34 |
| 389.45 | 4.47 | 4.47 |
| 407.47 | 4.83 | 4.83 |
| 423.58 | 4.93 | 4.93 |
| 492.07 | 4.88 | 4.88 |
| 479.58 | 6.53 | 6.53 |
| 507.43 | 4.87 | 4.87 |
| 480.96 | 2.61 | 2.61 |
| 441.98 | 5.79 | 5.79 |
| 415.90 | 3.34 | 3.34 |
| 490.95 | 2.81 | 2.81 |
| 416.32 | 4.23 | 4.23 |
| 437.93 | 3.33 | 3.33 |
| 332.30 | 2.57 | 2.57 |
| 369.23 | 3.13 | 3.13 |
| 411.93 | 4.45 | 4.45 |
| 353.42 | 3.91 | 3.91 |
| 405.49 | 4.74 | 4.74 |
| 455.38 | 5.62 | 5.62 |
| 433.51 | 5.45 | 5.45 |
| 446.59 | 5.17 | 5.17 |
| 570.57 | 5.50 | 5.50 |
| 509.61 | 6.53 | 6.53 |
| 286.71 | 4.13 | 4.13 |
| 407.51 | 3.81 | 3.81 |
| 486.96 | 3.83 | 3.83 |
| 376.51 | 3.58 | 3.58 |
| 492.62 | 5.15 | 5.15 |
| 483.57 | 6.14 | 6.14 |
| 492.94 | 4.11 | 4.11 |
| 325.78 | 2.09 | 2.09 |
| 433.89 | 4.11 | 4.11 |
| 468.51 | 3.23 | 3.23 |
| 385.22 | 4.06 | 4.06 |
| 419.48 | 5.00 | 5.00 |
| 529.04 | 5.96 | 5.96 |
| 411.53 | 3.81 | 3.81 |
| 403.87 | 4.94 | 4.94 |
| 463.99 | 6.06 | 6.06 |
| 509.45 | 4.36 | 4.36 |
| 338.21 | 4.70 | 4.70 |
| 400.95 | 4.29 | 4.29 |
| 467.57 | 6.52 | 6.52 |
| 437.51 | 4.20 | 4.20 |
| 421.54 | 4.20 | 4.20 |
| 431.94 | 3.49 | 3.49 |
| 421.49 | 5.03 | 5.03 |
| 432.39 | 4.80 | 4.80 |
| 463.99 | 6.06 | 6.06 |
| 392.52 | 5.24 | 5.24 |
| 338.21 | 4.40 | 4.40 |
| 455.54 | 4.23 | 4.23 |
| 501.51 | 4.04 | 4.04 |
| 433.55 | 5.45 | 5.45 |
| 376.46 | 3.81 | 3.81 |
| 402.41 | 4.46 | 4.46 |
| 460.57 | 6.55 | 6.55 |
| 431.90 | 3.39 | 3.39 |
| 498.35 | 6.19 | 6.19 |
| 339.80 | 1.85 | 1.85 |
| 403.94 | 3.71 | 3.71 |
| 238.27 | 0.37 | 0.37 |
| 431.90 | 3.04 | 3.04 |
| 462.89 | 3.45 | 3.45 |
| 401.88 | 3.03 | 3.03 |
| 403.87 | 4.66 | 4.66 |
| 420.54 | 5.37 | 5.37 |
| 317.39 | 5.26 | 5.26 |
| 419.87 | 3.17 | 3.17 |
| 477.61 | 2.95 | 2.95 |
| 282.30 | 3.48 | 3.48 |
| 371.49 | 5.08 | 5.08 |
| 466.59 | 6.18 | 6.18 |
| 395.43 | 3.11 | 3.11 |
| 579.72 | 4.35 | 4.35 |
| 494.98 | 3.00 | 3.00 |
| 408.55 | 3.16 | 3.16 |
| 388.42 | 4.83 | 4.83 |
| 407.50 | 4.30 | 4.30 |
| 494.98 | 3.00 | 3.00 |
| 450.33 | 4.76 | 4.76 |
| 469.51 | 5.96 | 5.96 |
| 339.44 | 3.81 | 3.81 |
| 423.83 | 3.63 | 3.63 |
| 385.42 | 5.56 | 5.56 |
| 526.61 | 5.75 | 5.75 |
| 328.44 | 3.45 | 3.45 |
| 396.49 | 4.88 | 4.88 |
| 429.33 | 2.54 | 2.54 |
| 512.72 | 7.12 | 7.12 |
| 433.89 | 4.11 | 4.11 |
| 539.63 | 6.54 | 6.54 |
| 416.57 | 5.08 | 5.08 |
| 430.66 | 4.70 | 4.70 |
| 416.57 | 4.84 | 4.84 |
| 451.50 | 5.09 | 5.09 |
| 345.78 | 3.59 | 3.59 |
| 344.21 | 3.80 | 3.80 |
| 429.54 | 5.48 | 5.48 |
| 448.52 | 4.29 | 4.29 |
| 408.91 | 6.19 | 6.19 |
| 430.46 | 3.93 | 3.93 |
| 438.94 | 4.23 | 4.23 |
| 362.93 | 4.78 | 4.78 |
| 402.88 | 4.91 | 4.91 |
| 402.23 | 3.64 | 3.64 |
| 325.78 | 2.18 | 2.18 |
| 438.94 | 2.28 | 2.28 |
| 569.66 | 6.55 | 6.55 |
| 376.87 | 3.57 | 3.57 |
| 341.21 | 2.03 | 2.03 |
| 417.98 | 5.79 | 5.79 |
| 459.91 | 3.45 | 3.45 |
| 453.56 | 3.69 | 3.69 |
| 474.95 | 3.97 | 3.97 |
| 432.61 | 3.89 | 3.89 |
| 492.62 | 3.10 | 3.10 |
| 374.44 | 4.98 | 4.98 |
| 456.98 | 2.87 | 2.87 |
| 412.54 | 5.27 | 5.27 |
| 339.82 | 5.24 | 5.24 |
| 457.49 | 4.99 | 4.99 |
| 292.33 | 1.27 | 1.27 |
| 306.36 | 1.58 | 1.58 |
| 378.43 | 6.21 | 6.21 |
| 427.45 | 3.63 | 3.63 |
| 576.65 | 4.60 | 4.60 |
| 528.12 | 4.61 | 4.61 |
| 445.93 | 3.78 | 3.78 |
| 401.96 | 4.95 | 4.95 |
| 606.21 | 6.32 | 6.32 |
| 423.49 | 3.89 | 3.89 |
| 399.49 | 4.56 | 4.56 |
| 343.39 | 4.76 | 4.76 |
| 415.49 | 3.56 | 3.56 |
| 381.51 | 3.82 | 3.82 |
| 509.61 | 6.53 | 6.53 |
| 573.98 | 5.03 | 5.03 |
| 499.95 | 4.69 | 4.69 |
| 477.75 | 7.32 | 7.32 |
| 458.91 | 5.98 | 5.98 |
| 444.62 | 5.98 | 5.98 |
| 386.93 | 4.00 | 4.00 |
| 417.51 | 5.03 | 5.03 |
| 450.54 | 4.55 | 4.55 |
| 431.90 | 3.67 | 3.67 |
| 417.48 | 4.37 | 4.37 |
| 537.47 | 3.48 | 3.48 |
| 424.91 | 1.89 | 1.89 |
| 497.47 | 4.50 | 4.50 |
| 459.91 | 3.53 | 3.53 |
| 427.46 | 0.34 | 0.34 |
| 440.31 | 3.62 | 3.62 |
| 360.26 | 3.78 | 3.78 |
| 508.58 | 5.56 | 5.56 |
| 383.26 | 3.44 | 3.44 |
| 445.93 | 3.78 | 3.78 |
| 388.51 | 5.66 | 5.66 |
| 467.71 | 6.91 | 6.91 |
| 581.76 | 3.62 | 3.62 |
| 474.33 | 3.87 | 3.87 |
| 488.98 | 4.28 | 4.28 |
| 491.86 | 4.89 | 4.89 |
| 452.49 | 3.97 | 3.97 |
| 434.58 | 5.03 | 5.03 |
| 528.72 | 4.19 | 4.19 |
| 430.66 | 4.70 | 4.70 |
| 577.50 | 5.39 | 5.39 |
| 386.93 | 3.90 | 3.90 |
| 441.48 | 4.02 | 4.02 |
| 460.97 | 3.97 | 3.97 |
| 463.99 | 6.69 | 6.69 |
| 375.44 | 3.19 | 3.19 |
| 424.53 | 4.86 | 4.86 |
| 471.54 | 4.93 | 4.93 |
| 445.91 | 2.54 | 2.54 |
| 446.57 | 3.12 | 3.12 |
| 604.66 | 4.43 | 4.43 |
| 485.33 | 3.19 | 3.19 |
| 434.58 | 5.03 | 5.03 |
| 433.58 | 4.69 | 4.69 |
| 402.61 | 3.92 | 3.92 |
| 451.96 | 3.64 | 3.64 |
| 539.63 | 6.54 | 6.54 |
| 493.51 | 4.86 | 4.86 |
| 431.51 | 5.96 | 5.96 |
| 417.42 | 5.04 | 5.04 |
| 429.52 | 3.95 | 3.95 |
| 397.50 | 4.70 | 4.70 |
| 384.39 | 3.47 | 3.47 |
| 419.89 | 3.36 | 3.36 |
| 382.49 | 3.87 | 3.87 |
| 488.61 | 4.71 | 4.71 |
| 551.65 | 4.94 | 4.94 |
| 423.49 | 3.74 | 3.74 |
| 498.95 | 4.56 | 4.56 |
| 477.87 | 5.28 | 5.28 |
| 402.47 | 4.25 | 4.25 |
| 465.89 | 3.51 | 3.51 |
| 409.46 | 3.50 | 3.50 |
| 572.59 | 3.78 | 3.78 |
| 431.52 | 4.88 | 4.88 |
| 385.46 | 4.31 | 4.31 |
| 369.83 | 1.86 | 1.86 |
| 451.96 | 3.64 | 3.64 |
| 305.38 | 4.58 | 4.58 |
| 393.87 | 5.25 | 5.25 |
| 540.09 | 5.27 | 5.27 |
| 467.57 | 3.70 | 3.70 |
| 397.54 | 3.90 | 3.90 |
| 506.93 | 5.93 | 5.93 |
| 446.60 | 5.37 | 5.37 |
| 518.71 | 3.68 | 3.68 |
| 395.53 | 5.19 | 5.19 |
| 416.64 | 4.31 | 4.31 |
| 429.86 | 6.36 | 6.36 |
| 290.36 | 1.88 | 1.88 |
| 392.91 | 3.37 | 3.37 |
| 432.31 | 4.67 | 4.67 |
| 382.49 | 4.10 | 4.10 |
| 309.41 | 3.89 | 3.89 |
| 407.42 | 5.10 | 5.10 |
| 411.53 | 3.81 | 3.81 |
| 468.64 | 3.69 | 3.69 |
| 390.46 | 5.23 | 5.23 |
| 434.56 | 5.46 | 5.46 |
| 415.90 | 3.97 | 3.97 |
| 442.94 | 5.59 | 5.59 |
| 406.53 | 6.03 | 6.03 |
| 451.96 | 3.64 | 3.64 |
| 433.94 | 4.95 | 4.95 |
| 449.55 | 5.07 | 5.07 |
| 453.34 | 5.74 | 5.74 |
| 377.47 | 5.05 | 5.05 |
| 306.36 | 1.66 | 1.66 |
| 486.66 | 5.76 | 5.76 |
| 422.87 | 5.35 | 5.35 |
| 375.47 | 4.74 | 4.74 |
| 371.57 | 3.66 | 3.66 |
| 439.31 | 3.79 | 3.79 |
| 399.51 | 4.74 | 4.74 |
| 387.57 | 3.40 | 3.40 |
| 357.43 | 3.53 | 3.53 |