ID: ALA2114753
Type: Functional
Description: PubChem BioAssay. qHTS assay for re-activators of p53 using a Luc reporter: Hit Validation. (Class of assay: confirmatory)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2114753
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
339.35 | 2.44 | 2.44 |
286.24 | 2.28 | 2.28 |
255.30 | 3.69 | 3.69 |
315.33 | 3.43 | 3.43 |
285.27 | 3.36 | 3.36 |
270.72 | 4.37 | 4.37 |
234.33 | 1.46 | 1.46 |
430.41 | 0.65 | 0.65 |
300.41 | 4.05 | 4.05 |
331.42 | 4.35 | 4.35 |
301.35 | 0.61 | 0.61 |
403.31 | 5.64 | 5.64 |
301.18 | 4.89 | 4.89 |
371.49 | 4.41 | 4.41 |
323.39 | 3.95 | 3.95 |
298.30 | 2.41 | 2.41 |
312.78 | 1.96 | 1.96 |
303.39 | 1.89 | 1.89 |
339.40 | 2.95 | 2.95 |
304.39 | 4.65 | 4.65 |
359.45 | 4.96 | 4.96 |
357.31 | 2.50 | 2.50 |
303.32 | 2.52 | 2.52 |
279.30 | 2.26 | 2.26 |
199.21 | 2.10 | 2.10 |
415.30 | 3.60 | 3.60 |
262.32 | 2.98 | 2.98 |
387.23 | 4.58 | 4.58 |
343.33 | 3.65 | 3.65 |
386.38 | 5.69 | 5.69 |
282.39 | 3.71 | 3.71 |
288.33 | 2.38 | 2.38 |
409.89 | 1.61 | 1.61 |
336.40 | 2.75 | 2.75 |
244.68 | 4.22 | 4.22 |
426.28 | 3.40 | 3.40 |
343.80 | 3.02 | 3.02 |
313.35 | 3.19 | 3.19 |
308.38 | 4.31 | 4.31 |
321.13 | 3.77 | 3.77 |
339.78 | 3.25 | 3.25 |
334.26 | 4.30 | 4.30 |
334.42 | 3.37 | 3.37 |
365.43 | 4.08 | 4.08 |
361.85 | 3.82 | 3.82 |
286.31 | 3.25 | 3.25 |
300.37 | 3.95 | 3.95 |
321.40 | 3.21 | 3.21 |
322.46 | 3.31 | 3.31 |
327.42 | 2.53 | 2.53 |
557.69 | 3.47 | 3.47 |
249.29 | 2.35 | 2.35 |
456.53 | 4.42 | 4.42 |
337.47 | 3.68 | 3.68 |
300.36 | 4.48 | 4.48 |
265.78 | 3.93 | 3.93 |
202.28 | 2.66 | 2.66 |
329.71 | 3.57 | 3.57 |
267.34 | 3.03 | 3.03 |
297.20 | 3.75 | 3.75 |
343.38 | 3.91 | 3.91 |
346.28 | 2.92 | 2.92 |
373.34 | 3.70 | 3.70 |
356.34 | 3.75 | 3.75 |
326.42 | 4.41 | 4.41 |
257.25 | 1.36 | 1.36 |
423.99 | 3.10 | 3.10 |
226.28 | 3.40 | 3.40 |
411.45 | 4.37 | 4.37 |
312.33 | 3.65 | 3.65 |
462.55 | 4.00 | 4.00 |
326.83 | 4.35 | 4.35 |
312.40 | 3.36 | 3.36 |
385.40 | 2.94 | 2.94 |
304.73 | 2.83 | 2.83 |
372.37 | 3.89 | 3.89 |
291.31 | 3.87 | 3.87 |
323.38 | 2.73 | 2.73 |
265.28 | 3.83 | 3.83 |
329.77 | 2.71 | 2.71 |
310.21 | 4.33 | 4.33 |
321.40 | 3.01 | 3.01 |
423.90 | 5.58 | 5.58 |
327.38 | 3.33 | 3.33 |
310.44 | 2.24 | 2.24 |
252.32 | 4.20 | 4.20 |
403.55 | 4.07 | 4.07 |
303.79 | 4.87 | 4.87 |
279.39 | 3.04 | 3.04 |
381.54 | 2.08 | 2.08 |
373.48 | 3.43 | 3.43 |
318.42 | 3.43 | 3.43 |
396.92 | 2.79 | 2.79 |
232.24 | 2.24 | 2.24 |
243.31 | 2.61 | 2.61 |
236.27 | 1.00 | 1.00 |
269.39 | 4.08 | 4.08 |
320.37 | 3.93 | 3.93 |
340.38 | 4.22 | 4.22 |
339.35 | 4.40 | 4.40 |
227.26 | 2.55 | 2.55 |
324.16 | 4.02 | 4.02 |
424.28 | 3.59 | 3.59 |
553.14 | 5.49 | 5.49 |
322.39 | 1.09 | 1.09 |
332.40 | 1.15 | 1.15 |
338.46 | 3.47 | 3.47 |
249.29 | 4.54 | 4.54 |
313.36 | 3.45 | 3.45 |
265.32 | 3.38 | 3.38 |
300.38 | 4.33 | 4.33 |
322.37 | 2.55 | 2.55 |
276.68 | 2.72 | 2.72 |
291.35 | 2.26 | 2.26 |
416.47 | 4.03 | 4.03 |
286.33 | 2.92 | 2.92 |
298.28 | 2.74 | 2.74 |
379.89 | 3.70 | 3.70 |
327.41 | 3.71 | 3.71 |
294.26 | -0.13 | -0.13 |
394.52 | 2.63 | 2.63 |
302.76 | 3.87 | 3.87 |
271.35 | 2.99 | 2.99 |
301.14 | 4.17 | 4.17 |
314.82 | 3.43 | 3.43 |
408.43 | 4.62 | 4.62 |
255.29 | 3.57 | 3.57 |
427.49 | 4.51 | 4.51 |
364.52 | 3.62 | 3.62 |
293.80 | 4.66 | 4.66 |
250.30 | 3.70 | 3.70 |
256.33 | 4.15 | 4.15 |
292.40 | 3.09 | 3.09 |
445.51 | 4.35 | 4.35 |
301.44 | 2.80 | 2.80 |
266.32 | 2.68 | 2.68 |
310.38 | 3.59 | 3.59 |
310.35 | 3.12 | 3.12 |
282.30 | 2.77 | 2.77 |
296.39 | 4.24 | 4.24 |
308.36 | 3.84 | 3.84 |
248.31 | 3.00 | 3.00 |
286.76 | 2.71 | 2.71 |
265.32 | 3.43 | 3.43 |
434.57 | 2.92 | 2.92 |
409.87 | 5.19 | 5.19 |
316.36 | 2.97 | 2.97 |
316.38 | 2.80 | 2.80 |
295.83 | 4.09 | 4.09 |
354.36 | 2.54 | 2.54 |
271.70 | 3.90 | 3.90 |
254.35 | 4.27 | 4.27 |
260.32 | 2.68 | 2.68 |
394.50 | 3.36 | 3.36 |
292.20 | 4.24 | 4.24 |
477.31 | 5.27 | 5.27 |
232.29 | 3.58 | 3.58 |
362.89 | 3.64 | 3.64 |
384.89 | 4.03 | 4.03 |
404.43 | 3.10 | 3.10 |
335.27 | 3.94 | 3.94 |
374.49 | 3.67 | 3.67 |
302.36 | 3.77 | 3.77 |
215.26 | 1.98 | 1.98 |
321.72 | 2.97 | 2.97 |
373.84 | 3.52 | 3.52 |
445.52 | 4.79 | 4.79 |
331.17 | 4.22 | 4.22 |
274.32 | 3.22 | 3.22 |
337.38 | 2.51 | 2.51 |
290.45 | 3.39 | 3.39 |
339.15 | 2.29 | 2.29 |
292.35 | 3.91 | 3.91 |
370.26 | 3.80 | 3.80 |
290.37 | 3.74 | 3.74 |
279.41 | 2.75 | 2.75 |
450.45 | 4.12 | 4.12 |
345.47 | 2.63 | 2.63 |
251.29 | 4.02 | 4.02 |
280.32 | 3.27 | 3.27 |
246.70 | 3.30 | 3.30 |
291.10 | 3.76 | 3.76 |
349.30 | 4.50 | 4.50 |
267.34 | 3.03 | 3.03 |
238.29 | 3.64 | 3.64 |
255.30 | 3.39 | 3.39 |
384.39 | 4.44 | 4.44 |
253.30 | 4.20 | 4.20 |
280.33 | 4.15 | 4.15 |
300.31 | 2.18 | 2.18 |
422.53 | 4.77 | 4.77 |
317.35 | 1.43 | 1.43 |
439.95 | 5.74 | 5.74 |
415.12 | 3.65 | 3.65 |
462.47 | 3.15 | 3.15 |
308.38 | 2.68 | 2.68 |
396.48 | 2.47 | 2.47 |
297.31 | 3.60 | 3.60 |
279.35 | 2.81 | 2.81 |
296.40 | 3.52 | 3.52 |
336.40 | 2.42 | 2.42 |
419.34 | 4.69 | 4.69 |
244.32 | 3.10 | 3.10 |
329.36 | 3.31 | 3.31 |
324.29 | 2.07 | 2.07 |
482.36 | 5.22 | 5.22 |
357.42 | 4.41 | 4.41 |
285.74 | 3.07 | 3.07 |
344.46 | 3.76 | 3.76 |
326.31 | 2.34 | 2.34 |
303.34 | 3.16 | 3.16 |
283.38 | 3.65 | 3.65 |
247.25 | 1.46 | 1.46 |
319.41 | 2.83 | 2.83 |
314.40 | 4.30 | 4.30 |
335.45 | 2.84 | 2.84 |
496.52 | 5.21 | 5.21 |
347.33 | 3.84 | 3.84 |
254.32 | 3.34 | 3.34 |
355.86 | 5.30 | 5.30 |
281.31 | 4.61 | 4.61 |
296.37 | 3.81 | 3.81 |
455.41 | 1.18 | 1.18 |
255.32 | 4.01 | 4.01 |
264.28 | 2.81 | 2.81 |
291.38 | 4.43 | 4.43 |
321.47 | 2.17 | 2.17 |
234.28 | 2.70 | 2.70 |
302.33 | 3.14 | 3.14 |
382.37 | 2.13 | 2.13 |
349.39 | 2.59 | 2.59 |
478.57 | 3.15 | 3.15 |
301.42 | 3.34 | 3.34 |
313.36 | 2.98 | 2.98 |
366.47 | 3.50 | 3.50 |
234.26 | 2.60 | 2.60 |
294.31 | 3.03 | 3.03 |
415.36 | 1.95 | 1.95 |
285.77 | 4.52 | 4.52 |
292.75 | 2.94 | 2.94 |
303.44 | 4.11 | 4.11 |
262.35 | 2.83 | 2.83 |
480.97 | 4.04 | 4.04 |
302.29 | 3.82 | 3.82 |
313.61 | 4.48 | 4.48 |
441.51 | 4.90 | 4.90 |
314.37 | 3.26 | 3.26 |
431.49 | 4.48 | 4.48 |
322.15 | 4.02 | 4.02 |
317.41 | 3.78 | 3.78 |
314.72 | 3.88 | 3.88 |
263.34 | 2.04 | 2.04 |
435.45 | 4.31 | 4.31 |
278.40 | 3.64 | 3.64 |
357.41 | 4.59 | 4.59 |
248.29 | 3.91 | 3.91 |
325.44 | 4.36 | 4.36 |
376.49 | 4.42 | 4.42 |
439.50 | 2.46 | 2.46 |
355.31 | 3.41 | 3.41 |
358.38 | 1.57 | 1.57 |
347.40 | 2.22 | 2.22 |
323.37 | 3.81 | 3.81 |
320.35 | 2.48 | 2.48 |
321.34 | 3.63 | 3.63 |
299.36 | 3.02 | 3.02 |
294.31 | 3.88 | 3.88 |
497.65 | 6.45 | 6.45 |
245.26 | 2.15 | 2.15 |
357.37 | 2.82 | 2.82 |
366.60 | 4.13 | 4.13 |
308.82 | 4.57 | 4.57 |
315.72 | 3.35 | 3.35 |
462.53 | 3.73 | 3.73 |
321.17 | 2.63 | 2.63 |
303.27 | 2.82 | 2.82 |
325.39 | 4.30 | 4.30 |
289.38 | 3.58 | 3.58 |
417.38 | 4.57 | 4.57 |
300.36 | 1.74 | 1.74 |
325.33 | 2.72 | 2.72 |
246.35 | 3.69 | 3.69 |
317.14 | 4.13 | 4.13 |
244.27 | 3.43 | 3.43 |
343.34 | 2.61 | 2.61 |
308.36 | 4.41 | 4.41 |
372.49 | 3.93 | 3.93 |
276.38 | 4.03 | 4.03 |
260.32 | 2.57 | 2.57 |
507.64 | 4.41 | 4.41 |
345.40 | 3.35 | 3.35 |
300.34 | 2.02 | 2.02 |
377.29 | 4.39 | 4.39 |
302.36 | 3.93 | 3.93 |
274.31 | 2.72 | 2.72 |
402.42 | 3.13 | 3.13 |
372.38 | 4.78 | 4.78 |
397.26 | 5.70 | 5.70 |
294.31 | 2.40 | 2.40 |
210.36 | 2.25 | 2.25 |
260.25 | 1.51 | 1.51 |
277.37 | 2.58 | 2.58 |
300.34 | 2.77 | 2.77 |
276.41 | 4.77 | 4.77 |
422.94 | 5.07 | 5.07 |
325.41 | 3.90 | 3.90 |
214.22 | 2.33 | 2.33 |
268.34 | 3.94 | 3.94 |
310.44 | 4.47 | 4.47 |
457.96 | 4.53 | 4.53 |
299.29 | 2.90 | 2.90 |
292.77 | 3.52 | 3.52 |
436.45 | 4.21 | 4.21 |
319.74 | 3.39 | 3.39 |
377.40 | 3.16 | 3.16 |
296.35 | 2.79 | 2.79 |
226.28 | 2.95 | 2.95 |
378.50 | 5.03 | 5.03 |
235.29 | 1.68 | 1.68 |
291.15 | 3.40 | 3.40 |
273.31 | 3.23 | 3.23 |
297.34 | 3.99 | 3.99 |
350.24 | 4.13 | 4.13 |
347.42 | 4.19 | 4.19 |
284.75 | 4.41 | 4.41 |
326.40 | 5.71 | 5.71 |
276.32 | 2.44 | 2.44 |
280.33 | 2.68 | 2.68 |
298.37 | 3.74 | 3.74 |
318.43 | 3.07 | 3.07 |
318.38 | 4.91 | 4.91 |
306.32 | 3.01 | 3.01 |
303.32 | 4.32 | 4.32 |
288.40 | 4.23 | 4.23 |
321.36 | 1.39 | 1.39 |
293.37 | 3.84 | 3.84 |
302.36 | 2.77 | 2.77 |
458.61 | 4.09 | 4.09 |
297.14 | 3.41 | 3.41 |
266.35 | 2.39 | 2.39 |
309.19 | 3.56 | 3.56 |
373.55 | 4.62 | 4.62 |
483.06 | 3.57 | 3.57 |
325.37 | 4.24 | 4.24 |
324.79 | 3.19 | 3.19 |
329.38 | 3.96 | 3.96 |
299.36 | 3.35 | 3.35 |
288.28 | 1.91 | 1.91 |
263.30 | 3.62 | 3.62 |
333.43 | 3.73 | 3.73 |
297.34 | 3.99 | 3.99 |
237.30 | 3.43 | 3.43 |
319.20 | 4.71 | 4.71 |
318.36 | 1.96 | 1.96 |
358.83 | 5.64 | 5.64 |
269.37 | 2.39 | 2.39 |
261.72 | 2.19 | 2.19 |
451.98 | 4.44 | 4.44 |
296.42 | 2.29 | 2.29 |
306.48 | 3.43 | 3.43 |
255.30 | 2.55 | 2.55 |
320.18 | 5.23 | 5.23 |
330.84 | 5.33 | 5.33 |
310.14 | 3.08 | 3.08 |
241.27 | 3.09 | 3.09 |
334.78 | 3.28 | 3.28 |
275.33 | 3.08 | 3.08 |
318.36 | 0.82 | 0.82 |
261.71 | 3.20 | 3.20 |
299.77 | 3.70 | 3.70 |
348.38 | 1.78 | 1.78 |
322.39 | 1.80 | 1.80 |
324.36 | 3.68 | 3.68 |
326.58 | 4.14 | 4.14 |
326.35 | 2.49 | 2.49 |
421.25 | 4.87 | 4.87 |
270.29 | 3.60 | 3.60 |
303.37 | 3.02 | 3.02 |
395.42 | 3.98 | 3.98 |
331.59 | 4.06 | 4.06 |
316.19 | 5.40 | 5.40 |
275.31 | 3.69 | 3.69 |
294.31 | 3.22 | 3.22 |
272.31 | 3.46 | 3.46 |
281.32 | 3.48 | 3.48 |
434.52 | 4.16 | 4.16 |
301.42 | 3.33 | 3.33 |
283.33 | 3.31 | 3.31 |
415.48 | 4.35 | 4.35 |
317.14 | 2.96 | 2.96 |
305.18 | 4.40 | 4.40 |
265.32 | 3.15 | 3.15 |
337.23 | 5.16 | 5.16 |
313.36 | 4.04 | 4.04 |
285.35 | 4.37 | 4.37 |
309.15 | 3.68 | 3.68 |
323.78 | 4.98 | 4.98 |
282.37 | 3.84 | 3.84 |
471.33 | 5.42 | 5.42 |
347.37 | 4.12 | 4.12 |
327.34 | 2.97 | 2.97 |
326.45 | 4.25 | 4.25 |
272.74 | 3.70 | 3.70 |
363.16 | 4.67 | 4.67 |
373.41 | 3.26 | 3.26 |
320.41 | 3.21 | 3.21 |
228.25 | 2.63 | 2.63 |
396.32 | 4.16 | 4.16 |
327.29 | 3.07 | 3.07 |
247.21 | 2.14 | 2.14 |
318.38 | 4.22 | 4.22 |
239.27 | 3.81 | 3.81 |
273.32 | 2.75 | 2.75 |
306.73 | 4.54 | 4.54 |
272.74 | 3.70 | 3.70 |
327.41 | 2.81 | 2.81 |
296.21 | 4.79 | 4.79 |
343.41 | 2.49 | 2.49 |
372.35 | 5.19 | 5.19 |
310.40 | 4.28 | 4.28 |
227.26 | 2.95 | 2.95 |
284.31 | 2.96 | 2.96 |
296.37 | 3.25 | 3.25 |
251.29 | 3.42 | 3.42 |
344.47 | 3.41 | 3.41 |
308.38 | 2.72 | 2.72 |
303.36 | 4.44 | 4.44 |
328.18 | 4.32 | 4.32 |
247.29 | 3.70 | 3.70 |
397.48 | 5.12 | 5.12 |
407.52 | 5.30 | 5.30 |
332.41 | 3.10 | 3.10 |
328.81 | 2.22 | 2.22 |
324.41 | 4.22 | 4.22 |
307.38 | 1.47 | 1.47 |
502.54 | 4.86 | 4.86 |
311.20 | 3.77 | 3.77 |
296.40 | 4.01 | 4.01 |
348.74 | 2.19 | 2.19 |
436.56 | 5.07 | 5.07 |
249.29 | 2.19 | 2.19 |
378.46 | 3.20 | 3.20 |
280.35 | 2.67 | 2.67 |
429.44 | 4.16 | 4.16 |
260.25 | 2.01 | 2.01 |
292.75 | 1.96 | 1.96 |
269.33 | 2.86 | 2.86 |
394.36 | 4.51 | 4.51 |
290.43 | 2.80 | 2.80 |
314.34 | 3.24 | 3.24 |
316.15 | 4.01 | 4.01 |
221.28 | 3.21 | 3.21 |
391.74 | 4.33 | 4.33 |
278.38 | 2.79 | 2.79 |
279.34 | 1.97 | 1.97 |
296.39 | 3.63 | 3.63 |
393.87 | 3.16 | 3.16 |
294.38 | 3.32 | 3.32 |
256.33 | 2.53 | 2.53 |
437.93 | 3.11 | 3.11 |
355.30 | 4.15 | 4.15 |
370.41 | 0.46 | 0.46 |
325.33 | 2.46 | 2.46 |
321.60 | 3.26 | 3.26 |
450.61 | 3.96 | 3.96 |
341.27 | 3.84 | 3.84 |
459.98 | 4.88 | 4.88 |
360.41 | 4.65 | 4.65 |
236.27 | 3.45 | 3.45 |
249.27 | 3.63 | 3.63 |
370.40 | 3.98 | 3.98 |
350.41 | 4.40 | 4.40 |
404.51 | 3.94 | 3.94 |
253.28 | 4.05 | 4.05 |
421.32 | 3.70 | 3.70 |
311.36 | 1.22 | 1.22 |
342.20 | 3.95 | 3.95 |
318.80 | 3.51 | 3.51 |
246.66 | 2.38 | 2.38 |
399.39 | 2.69 | 2.69 |
308.34 | 3.22 | 3.22 |
287.33 | 4.15 | 4.15 |
458.48 | 4.65 | 4.65 |
403.54 | 2.48 | 2.48 |
341.27 | 3.76 | 3.76 |
311.34 | 5.09 | 5.09 |
378.42 | 2.32 | 2.32 |
276.73 | 2.97 | 2.97 |
400.44 | 3.80 | 3.80 |
256.33 | 3.38 | 3.38 |
302.76 | 2.71 | 2.71 |
400.89 | 4.23 | 4.23 |
335.79 | 3.92 | 3.92 |
484.14 | 4.93 | 4.93 |
391.43 | 3.29 | 3.29 |
318.17 | 3.00 | 3.00 |
360.44 | 4.42 | 4.42 |
278.32 | 3.08 | 3.08 |
514.31 | 3.68 | 3.68 |
299.33 | 2.25 | 2.25 |
260.32 | 1.72 | 1.72 |
421.45 | 5.11 | 5.11 |
433.43 | 1.85 | 1.85 |
304.35 | 3.09 | 3.09 |
293.32 | 4.03 | 4.03 |
244.25 | 1.64 | 1.64 |
313.38 | 3.13 | 3.13 |
312.33 | 4.29 | 4.29 |
292.41 | 1.34 | 1.34 |
330.37 | 3.21 | 3.21 |
250.35 | 2.88 | 2.88 |
309.30 | 3.94 | 3.94 |
276.34 | 4.06 | 4.06 |
257.36 | 4.17 | 4.17 |
330.40 | 3.81 | 3.81 |
508.39 | 2.09 | 2.09 |
273.31 | 3.25 | 3.25 |
313.28 | 1.61 | 1.61 |
337.45 | 4.23 | 4.23 |
299.31 | 2.55 | 2.55 |
280.29 | 2.49 | 2.49 |
291.36 | 3.14 | 3.14 |
332.41 | 4.16 | 4.16 |
297.34 | 3.47 | 3.47 |
351.37 | 2.82 | 2.82 |
353.43 | 5.30 | 5.30 |
390.46 | 4.53 | 4.53 |
285.33 | 2.15 | 2.15 |
290.75 | 2.53 | 2.53 |
263.32 | 2.79 | 2.79 |
278.36 | 3.38 | 3.38 |
229.24 | 1.33 | 1.33 |
257.27 | 2.37 | 2.37 |
393.32 | 3.07 | 3.07 |
418.49 | 4.87 | 4.87 |
294.31 | 3.40 | 3.40 |
307.78 | 3.80 | 3.80 |
276.29 | 2.71 | 2.71 |
306.34 | 2.69 | 2.69 |
347.42 | 2.81 | 2.81 |
445.91 | 6.03 | 6.03 |
267.33 | 2.91 | 2.91 |
291.31 | 3.38 | 3.38 |
288.26 | 2.15 | 2.15 |
357.80 | 2.55 | 2.55 |
319.34 | 3.40 | 3.40 |
381.23 | 1.56 | 1.56 |
254.29 | 2.89 | 2.89 |
263.39 | 2.69 | 2.69 |
281.31 | 3.61 | 3.61 |
463.40 | 3.07 | 3.07 |
266.30 | 2.47 | 2.47 |
343.84 | 4.06 | 4.06 |
298.34 | 3.07 | 3.07 |
485.34 | 5.81 | 5.81 |
231.26 | 0.82 | 0.82 |
536.00 | 3.21 | 3.21 |
275.42 | 3.21 | 3.21 |
212.27 | 2.14 | 2.14 |