Basic Information
ID: ALA2114772
Type: Functional
Description: PubChem BioAssay. Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2): Fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA). (Class of assay: confirmatory)
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA2114772
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 227.29 | 3.05 | 3.05 |
| 195.17 | 1.65 | 1.65 |
| 453.29 | 3.36 | 3.36 |
| 257.31 | 3.06 | 3.06 |
| 249.27 | 2.91 | 2.91 |
| 324.38 | 3.49 | 3.49 |
| 265.31 | 0.50 | 0.50 |
| 307.26 | -1.29 | -1.29 |
| 294.29 | 1.83 | 1.83 |
| 447.92 | 4.06 | 4.06 |
| 404.82 | ||
| 297.35 | 0.16 | 0.16 |
| 317.28 | 3.80 | 3.80 |
| 475.63 | 5.11 | 5.11 |
| 338.12 | 4.01 | 4.01 |
| 339.39 | 0.73 | 0.73 |
| 265.31 | 0.50 | 0.50 |
| 489.65 | 4.64 | 4.64 |
| 241.08 | 2.54 | 2.54 |
| 255.10 | 2.85 | 2.85 |
| 339.35 | 4.19 | 4.19 |
| 294.31 | 2.47 | 2.47 |
| 545.90 | 4.92 | 4.92 |
| 461.61 | 3.45 | 3.45 |
| 373.66 | 3.25 | 3.25 |
| 306.67 | 3.23 | 3.23 |
| 414.37 | 3.56 | 3.56 |
| 403.37 | 2.41 | 2.41 |
| 248.28 | 2.08 | 2.08 |
| 377.44 | 1.84 | 1.84 |
| 275.30 | 3.20 | 3.20 |
| 528.10 | 3.46 | 3.46 |
| 548.07 | 3.83 | 3.83 |
| 402.04 | 3.41 | 3.41 |
| 523.41 | 5.24 | 5.24 |
| 379.85 | 3.28 | 3.28 |
| 415.90 | 3.34 | 3.34 |
| 437.56 | 4.27 | 4.27 |
| 252.66 | 2.58 | 2.58 |
| 278.31 | 2.77 | 2.77 |
| 313.14 | 2.67 | 2.67 |
| 449.36 | 3.08 | 3.08 |
| 478.96 | 5.13 | 5.13 |
| 468.61 | 4.58 | 4.58 |
| 318.20 | 2.25 | 2.25 |
| 332.30 | 2.57 | 2.57 |
| 444.53 | 2.60 | 2.60 |
| 351.42 | 2.52 | 2.52 |
| 277.28 | 2.35 | 2.35 |
| 392.01 | 1.56 | 1.56 |
| 319.84 | 2.34 | 2.34 |
| 312.18 | 4.38 | 4.38 |
| 374.34 | 2.50 | 2.50 |
| 347.83 | 3.37 | 3.37 |
| 505.67 | 5.11 | 5.11 |
| 410.74 | 3.75 | 3.75 |
| 291.33 | 2.22 | 2.22 |
| 305.33 | 3.47 | 3.47 |
| 320.27 | 2.71 | 2.71 |
| 448.10 | 2.38 | 2.38 |
| 349.18 | 3.43 | 3.43 |
| 311.17 | 3.00 | 3.00 |
| 236.73 | 1.94 | 1.94 |
| 459.36 | 2.67 | 2.67 |
| 431.90 | 3.04 | 3.04 |
| 350.36 | 1.81 | 1.81 |
| 329.81 | 4.06 | 4.06 |
| 245.28 | 3.19 | 3.19 |
| 370.47 | 4.04 | 4.04 |
| 271.10 | 2.55 | 2.55 |
| 445.61 | 3.75 | 3.75 |
| 300.27 | 2.56 | 2.56 |
| 285.31 | 1.69 | 1.69 |
| 541.94 | 5.34 | 5.34 |
| 373.80 | 4.84 | 4.84 |
| 278.29 | 2.13 | 2.13 |
| 376.75 | 2.38 | 2.38 |
| 499.57 | 4.60 | 4.60 |
| 328.39 | 3.35 | 3.35 |
| 328.38 | 3.43 | 3.43 |
| 298.32 | 2.43 | 2.43 |
| 241.07 | 3.61 | 3.61 |
| 385.84 | 2.74 | 2.74 |
| 513.40 | 5.78 | 5.78 |
| 278.31 | 3.94 | 3.94 |
| 402.62 | 4.17 | 4.17 |
| 254.74 | 3.05 | 3.05 |
| 300.32 | 2.80 | 2.80 |
| 305.33 | 3.47 | 3.47 |
| 459.91 | 3.07 | 3.07 |
| 354.19 | 2.78 | 2.78 |
| 300.32 | 2.80 | 2.80 |
| 317.56 | 3.09 | 3.09 |
| 342.14 | 1.92 | 1.92 |
| 418.49 | 2.06 | 2.06 |
| 537.39 | 4.22 | 4.22 |
| 302.33 | 2.30 | 2.30 |
| 418.25 | 4.95 | 4.95 |
| 383.24 | 1.96 | 1.96 |
| 302.33 | 3.08 | 3.08 |
| 343.75 | 3.28 | 3.28 |
| 240.65 | -0.01 | -0.01 |
| 264.28 | 2.47 | 2.47 |
| 454.02 | 3.98 | 3.98 |
| 373.21 | 2.32 | 2.32 |
| 439.83 | 2.29 | 2.29 |
| 463.83 | 4.15 | 4.15 |
| 245.28 | 3.19 | 3.19 |
| 277.74 | 3.73 | 3.73 |
| 264.26 | 1.82 | 1.82 |
| 365.01 | 4.22 | 4.22 |
| 303.70 | 3.85 | 3.85 |
| 303.32 | 3.81 | 3.81 |
| 391.47 | 2.15 | 2.15 |
| 342.40 | 4.54 | 4.54 |
| 427.29 | 2.01 | 2.01 |
| 196.21 | 2.51 | 2.51 |
| 298.73 | 3.12 | 3.12 |
| 373.82 | 1.84 | 1.84 |
| 278.31 | 3.24 | 3.24 |
| 275.26 | 2.50 | 2.50 |
| 456.56 | 3.68 | 3.68 |
| 481.36 | 2.24 | 2.24 |
| 473.92 | 4.11 | 4.11 |
| 330.34 | 4.17 | 4.17 |
| 344.01 | 3.07 | 3.07 |
| 283.35 | 3.53 | 3.53 |
| 457.53 | 4.67 | 4.67 |
| 334.40 | 3.49 | 3.49 |
| 415.90 | 3.97 | 3.97 |
| 460.32 | 3.97 | 3.97 |
| 228.25 | 2.22 | 2.22 |
| 373.80 | 2.87 | 2.87 |
| 312.76 | 4.59 | 4.59 |
| 223.18 | 1.67 | 1.67 |
| 478.96 | 5.13 | 5.13 |
| 392.80 | 2.76 | 2.76 |
| 234.25 | 1.77 | 1.77 |
| 415.45 | 5.86 | 5.86 |
| 309.32 | 2.92 | 2.92 |
| 243.26 | 3.49 | 3.49 |
| 445.88 | 2.76 | 2.76 |
| 317.78 | 1.38 | 1.38 |
| 365.41 | 3.47 | 3.47 |
| 382.46 | 4.50 | 4.50 |
| 370.19 | 2.37 | 2.37 |
| 332.30 | 2.57 | 2.57 |
| 445.48 | 4.26 | 4.26 |
| 275.31 | 2.37 | 2.37 |
| 599.22 | 5.20 | 5.20 |
| 492.15 | 6.80 | 6.80 |
| 333.32 | 2.25 | 2.25 |
| 518.56 | 1.14 | 1.14 |
| 293.41 | 4.34 | 4.34 |
| 317.86 | 3.53 | 3.53 |
| 245.28 | 3.19 | 3.19 |
| 466.53 | 1.69 | 1.69 |
| 414.40 | 2.97 | 2.97 |
| 390.34 | 2.45 | 2.45 |
| 318.79 | 3.36 | 3.36 |
| 756.86 | 1.54 | 1.54 |
| 508.60 | 2.07 | 2.07 |
| 302.33 | 2.84 | 2.84 |
| 260.34 | 4.79 | 4.79 |
| 237.26 | 2.57 | 2.57 |
| 452.98 | 3.29 | 3.29 |
| 284.34 | 3.01 | 3.01 |
| 450.62 | 6.70 | 6.70 |
| 475.75 | 3.99 | 3.99 |
| 347.20 | 1.71 | 1.71 |
| 486.57 | -0.34 | -0.34 |
| 292.38 | 2.61 | 2.61 |
| 277.28 | 2.38 | 2.38 |
| 590.76 | 5.90 | 5.90 |
| 298.37 | 3.01 | 3.01 |
| 398.29 | 5.06 | 5.06 |
| 410.95 | 3.52 | 3.52 |
| 804.84 | 1.31 | 1.31 |
| 363.24 | 3.46 | 3.46 |
| 548.63 | 1.36 | 1.36 |
| 346.47 | 3.42 | 3.42 |
| 549.99 | ||
| 458.04 | 5.09 | 5.09 |
| 329.40 | 3.75 | 3.75 |
| 406.48 | 0.95 | 0.95 |
| 311.29 | 3.42 | 3.42 |
| 439.00 | 4.30 | 4.30 |
| 365.38 | 4.03 | 4.03 |
| 481.64 | 4.72 | 4.72 |
| 310.31 | 2.61 | 2.61 |
| 325.27 | -2.23 | -2.23 |
| 206.24 | 3.35 | 3.35 |
| 721.74 | 3.07 | 3.07 |
| 278.25 | 2.44 | 2.44 |
| 451.01 | 4.44 | 4.44 |
| 305.38 | 3.17 | 3.17 |
| 370.24 | 4.15 | 4.15 |
| 317.71 | 1.75 | 1.75 |
| 264.28 | 3.01 | 3.01 |
| 388.50 | 3.99 | 3.99 |
| 446.54 | 3.39 | 3.39 |
| 404.50 | 2.82 | 2.82 |
| 334.30 | 4.46 | 4.46 |
| 362.47 | 2.25 | 2.25 |
| 332.44 | 3.19 | 3.19 |
| 487.63 | 4.64 | 4.64 |
| 367.29 | 3.29 | 3.29 |
| 595.59 | 2.27 | 2.27 |
| 489.00 | 5.20 | 5.20 |
| 316.32 | 2.63 | 2.63 |
| 305.36 | 2.53 | 2.53 |
| 319.38 | 2.86 | 2.86 |
| 300.27 | 1.17 | 1.17 |
| 317.39 | 2.99 | 2.99 |
| 292.38 | 2.61 | 2.61 |
| 403.52 | 4.88 | 4.88 |
| 419.52 | 4.58 | 4.58 |
| 433.55 | 4.89 | 4.89 |
| 441.96 | 5.09 | 5.09 |
| 453.97 | 5.24 | 5.24 |
| 509.60 | 4.61 | 4.61 |
| 403.52 | 4.88 | 4.88 |
| 449.55 | 4.59 | 4.59 |
| 383.88 | 4.30 | 4.30 |
| 479.57 | 4.60 | 4.60 |
| 433.55 | 4.89 | 4.89 |
| 419.52 | 4.58 | 4.58 |
| 423.94 | 5.23 | 5.23 |
| 470.61 | 3.35 | 3.35 |
| 544.82 | 2.47 | 2.47 |
| 497.40 | 4.42 | 4.42 |
| 450.51 | 2.48 | 2.48 |