Basic Information
ID: ALA2114791
Type: Functional
Description: PubChem BioAssay. Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2. (Class of assay: confirmatory)
Organism: Staphylococcus aureus subsp. aureus N315
Activity Charts
Bioactivity
Activity Types for Assay ALA2114791
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.37 | 3.37 |
| 538.46 | 5.13 | 5.13 |
| 544.53 | 6.81 | 6.81 |
| 282.34 | 1.93 | 1.93 |
| 484.00 | 4.70 | 4.70 |
| 415.47 | 2.26 | 2.26 |
| 274.37 | 4.32 | 4.32 |
| 697.14 | 5.37 | 5.37 |
| 608.18 | 8.95 | 8.95 |
| 492.56 | 4.21 | 4.21 |
| 339.42 | 4.08 | 4.08 |
| 539.04 | 5.01 | 5.01 |
| 304.34 | 2.76 | 2.76 |
| 434.59 | 3.42 | 3.42 |
| 321.34 | 2.59 | 2.59 |
| 488.55 | 4.69 | 4.69 |
| 364.52 | 3.78 | 3.78 |
| 414.49 | 2.17 | 2.17 |
| 364.40 | 3.52 | 3.52 |
| 475.60 | 4.24 | 4.24 |
| 456.96 | 4.85 | 4.85 |
| 531.61 | 3.72 | 3.72 |
| 341.46 | 4.24 | 4.24 |
| 493.98 | 3.92 | 3.92 |
| 508.62 | 5.79 | 5.79 |
| 561.66 | ||
| 308.45 | 4.43 | 4.43 |
| 409.40 | 2.95 | 2.95 |
| 478.60 | 4.11 | 4.11 |
| 361.43 | 3.83 | 3.83 |
| 434.41 | 1.51 | 1.51 |
| 574.46 | 5.82 | 5.82 |
| 483.48 | 5.32 | 5.32 |
| 468.46 | 2.05 | 2.05 |
| 458.61 | 4.03 | 4.03 |
| 492.63 | 4.42 | 4.42 |
| 458.50 | 4.50 | 4.50 |
| 376.33 | ||
| 398.45 | 5.27 | 5.27 |
| 380.30 | 4.43 | 4.43 |
| 289.34 | 4.08 | 4.08 |
| 415.41 | 4.32 | 4.32 |
| 492.60 | 5.90 | 5.90 |
| 384.44 | 3.02 | 3.02 |
| 530.56 | 5.21 | 5.21 |
| 441.49 | 4.69 | 4.69 |
| 361.39 | 2.93 | 2.93 |
| 491.60 | 3.57 | 3.57 |
| 460.52 | 4.22 | 4.22 |
| 470.48 | 5.25 | 5.25 |
| 491.57 | 5.08 | 5.08 |
| 459.56 | 5.30 | 5.30 |
| 616.60 | 7.25 | 7.25 |
| 412.86 | 3.65 | 3.65 |
| 466.50 | 4.90 | 4.90 |
| 514.63 | 6.03 | 6.03 |
| 451.58 | 4.83 | 4.83 |
| 548.64 | 4.54 | 4.54 |
| 546.67 | 5.72 | 5.72 |
| 478.60 | 4.11 | 4.11 |
| 676.69 | 5.24 | 5.24 |
| 385.47 | 4.53 | 4.53 |
| 469.52 | 4.76 | 4.76 |
| 358.42 | 3.73 | 3.73 |
| 493.54 | 3.78 | 3.78 |
| 475.43 | 5.61 | 5.61 |
| 419.51 | 4.62 | 4.62 |
| 366.40 | 4.37 | 4.37 |
| 544.64 | 4.02 | 4.02 |
| 487.57 | 4.81 | 4.81 |
| 571.61 | 4.28 | 4.28 |
| 492.58 | 4.49 | 4.49 |
| 459.53 | 5.39 | 5.39 |
| 407.81 | 3.93 | 3.93 |
| 309.76 | 4.42 | 4.42 |
| 405.48 | 4.31 | 4.31 |
| 429.48 | 0.74 | 0.74 |
| 245.27 | 1.15 | 1.15 |
| 496.59 | 5.12 | 5.12 |
| 637.14 | 5.53 | 5.53 |
| 519.61 | 4.09 | 4.09 |
| 568.93 | 6.24 | 6.24 |
| 464.57 | 4.86 | 4.86 |
| 419.19 | 2.04 | 2.04 |
| 367.37 | 1.82 | 1.82 |
| 463.53 | 5.46 | 5.46 |
| 543.60 | 5.24 | 5.24 |
| 380.54 | 4.88 | 4.88 |
| 404.29 | 4.54 | 4.54 |
| 502.02 | 5.05 | 5.05 |
| 351.39 | 3.47 | 3.47 |
| 335.39 | 4.51 | 4.51 |
| 434.55 | 5.36 | 5.36 |
| 512.59 | 5.87 | 5.87 |
| 346.35 | 3.99 | 3.99 |
| 463.97 | 4.78 | 4.78 |
| 290.24 | 4.64 | 4.64 |
| 402.45 | 4.86 | 4.86 |
| 486.64 | 4.63 | 4.63 |
| 416.48 | 4.53 | 4.53 |
| 416.53 | 5.64 | 5.64 |
| 494.57 | 4.77 | 4.77 |
| 528.59 | 5.57 | 5.57 |
| 448.49 | 5.41 | 5.41 |
| 569.60 | 4.83 | 4.83 |
| 484.49 | 3.94 | 3.94 |
| 424.45 | 3.14 | 3.14 |
| 528.06 | 5.68 | 5.68 |
| 479.58 | 5.18 | 5.18 |
| 527.61 | 4.14 | 4.14 |
| 492.63 | 4.42 | 4.42 |
| 513.55 | 5.00 | 5.00 |
| 477.54 | 4.08 | 4.08 |
| 518.66 | 5.15 | 5.15 |
| 456.53 | 3.86 | 3.86 |
| 379.69 | 4.96 | 4.96 |
| 421.41 | 4.70 | 4.70 |
| 408.56 | 5.17 | 5.17 |
| 459.92 | 4.11 | 4.11 |
| 426.84 | 4.92 | 4.92 |
| 450.91 | 4.74 | 4.74 |
| 496.62 | 5.32 | 5.32 |
| 434.91 | 2.51 | 2.51 |
| 514.56 | 5.98 | 5.98 |
| 418.32 | 4.84 | 4.84 |
| 550.62 | 3.32 | 3.32 |
| 434.55 | 5.36 | 5.36 |
| 439.50 | 3.76 | 3.76 |
| 482.33 | 3.64 | 3.64 |
| 309.76 | 4.42 | 4.42 |
| 366.52 | 4.49 | 4.49 |
| 486.58 | 5.41 | 5.41 |
| 527.62 | 5.42 | 5.42 |
| 507.02 | 6.55 | 6.55 |
| 491.66 | 5.01 | 5.01 |
| 583.70 | 2.29 | 2.29 |
| 432.55 | 5.12 | 5.12 |
| 460.92 | 4.89 | 4.89 |
| 543.01 | 2.97 | 2.97 |
| 510.52 | 4.21 | 4.21 |
| 415.47 | 2.58 | 2.58 |
| 476.52 | 3.00 | 3.00 |
| 389.21 | 3.28 | 3.28 |
| 399.93 | 5.14 | 5.14 |
| 469.55 | 2.81 | 2.81 |
| 463.54 | 5.50 | 5.50 |
| 521.02 | 6.06 | 6.06 |
| 398.45 | 5.27 | 5.27 |
| 527.61 | 5.57 | 5.57 |
| 380.44 | 3.99 | 3.99 |
| 460.56 | 3.66 | 3.66 |
| 454.51 | 4.07 | 4.07 |
| 483.58 | 3.12 | 3.12 |
| 354.44 | 3.72 | 3.72 |
| 522.99 | 3.44 | 3.44 |
| 495.56 | 4.79 | 4.79 |
| 412.50 | 5.17 | 5.17 |
| 378.46 | 4.04 | 4.04 |
| 578.47 | 5.99 | 5.99 |
| 504.55 | 4.00 | 4.00 |
| 512.59 | 5.87 | 5.87 |
| 415.45 | 3.84 | 3.84 |
| 467.55 | 5.31 | 5.31 |
| 464.54 | 4.72 | 4.72 |
| 478.96 | 4.53 | 4.53 |
| 365.41 | 3.78 | 3.78 |
| 522.53 | 5.23 | 5.23 |
| 365.41 | 3.78 | 3.78 |
| 497.55 | 5.03 | 5.03 |
| 498.36 | 4.80 | 4.80 |
| 354.41 | 3.56 | 3.56 |
| 803.32 | 0.24 | 0.24 |
| 418.45 | 5.87 | 5.87 |
| 603.41 | 9.05 | 9.05 |
| 359.36 | 4.40 | 4.40 |
| 359.36 | 4.40 | 4.40 |
| 561.64 | 3.73 | 3.73 |
| 343.26 | 3.82 | 3.82 |
| 315.35 | 3.54 | 3.54 |
| 389.41 | 3.38 | 3.38 |
| 476.36 | 3.78 | 3.78 |
| 308.34 | 4.30 | 4.30 |
| 277.19 | 1.24 | 1.24 |
| 411.53 | 5.26 | 5.26 |
| 444.53 | 5.17 | 5.17 |
| 415.45 | 3.84 | 3.84 |
| 502.58 | 6.69 | 6.69 |
| 720.02 | 6.03 | 6.03 |
| 375.49 | 4.41 | 4.41 |
| 416.48 | 4.53 | 4.53 |
| 712.04 | 6.37 | 6.37 |
| 730.83 | 5.80 | 5.80 |
| 433.53 | 3.46 | 3.46 |
| 505.60 | 6.40 | 6.40 |
| 493.56 | 4.28 | 4.28 |
| 531.57 | 5.12 | 5.12 |
| 733.95 | 4.59 | 4.59 |
| 401.36 | 3.44 | 3.44 |
| 434.55 | 5.36 | 5.36 |
| 547.64 | 7.04 | 7.04 |
| 395.91 | 4.76 | 4.76 |
| 560.84 | 2.60 | 2.60 |
| 539.54 | 6.15 | 6.15 |
| 441.49 | 4.69 | 4.69 |
| 439.58 | 5.79 | 5.79 |
| 458.86 | 5.96 | 5.96 |
| 577.44 | 3.58 | 3.58 |
| 552.66 | 3.93 | 3.93 |
| 498.52 | 3.92 | 3.92 |
| 349.46 | 5.28 | 5.28 |
| 401.50 | 4.28 | 4.28 |
| 471.47 | -0.54 | -0.54 |
| 336.35 | 3.11 | 3.11 |
| 451.11 | 5.35 | 5.35 |
| 549.36 | 4.31 | 4.31 |
| 485.52 | 4.01 | 4.01 |
| 411.42 | 4.57 | 4.57 |
| 359.39 | 3.51 | 3.51 |
| 420.43 | 2.28 | 2.28 |
| 270.29 | 1.47 | 1.47 |
| 748.86 | 5.03 | 5.03 |
| 445.59 | 4.63 | 4.63 |
| 550.46 | 6.85 | 6.85 |
| 727.91 | 3.86 | 3.86 |
| 325.32 | 1.35 | 1.35 |
| 594.80 | 4.02 | 4.02 |
| 732.86 | 5.80 | 5.80 |
| 521.40 | 5.87 | 5.87 |
| 504.62 | 4.00 | 4.00 |
| 467.58 | 4.51 | 4.51 |
| 350.38 | 3.86 | 3.86 |
| 416.55 | 4.33 | 4.33 |
| 406.44 | 4.43 | 4.43 |
| 459.89 | 4.78 | 4.78 |
| 356.39 | 4.25 | 4.25 |
| 506.63 | 4.55 | 4.55 |
| 411.49 | 3.07 | 3.07 |
| 480.98 | 4.95 | 4.95 |
| 505.56 | 4.09 | 4.09 |
| 484.38 | 5.05 | 5.05 |
| 418.32 | 3.88 | 3.88 |
| 484.38 | 5.05 | 5.05 |
| 491.53 | 3.70 | 3.70 |
| 496.62 | 4.47 | 4.47 |
| 524.65 | 4.01 | 4.01 |
| 420.24 | 3.21 | 3.21 |
| 563.08 | 5.00 | 5.00 |
| 534.45 | 5.11 | 5.11 |
| 503.01 | 4.51 | 4.51 |
| 381.44 | 5.32 | 5.32 |
| 441.51 | 3.08 | 3.08 |
| 348.36 | 3.31 | 3.31 |