Basic Information
ID: ALA2114792
Type: Functional
Description: PubChem BioAssay. Counterscreen for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1). (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114792
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.16 | -0.74 | -0.74 |
| 234.20 | 2.78 | 2.78 |
| 256.35 | 2.12 | 2.12 |
| 254.33 | 2.03 | 2.03 |
| 356.47 | 2.02 | 2.02 |
| 260.31 | 3.17 | 3.17 |
| 340.47 | 2.93 | 2.93 |
| 401.87 | 2.73 | 2.73 |
| 448.39 | 4.86 | 4.86 |
| 410.61 | 4.27 | 4.27 |
| 258.33 | 0.71 | 0.71 |
| 312.45 | 3.88 | 3.88 |
| 417.63 | 6.79 | 6.79 |
| 328.29 | 3.37 | 3.37 |
| 396.87 | 2.13 | 2.13 |
| 370.67 | 3.03 | 3.03 |
| 410.74 | 3.93 | 3.93 |
| 212.68 | 1.37 | 1.37 |
| 418.99 | 4.81 | 4.81 |
| 203.67 | 0.65 | 0.65 |
| 337.85 | 2.96 | 2.96 |
| 501.32 | 0.26 | 0.26 |
| 455.51 | 1.92 | 1.92 |
| 260.13 | 0.91 | 0.91 |
| 219.67 | 0.35 | 0.35 |
| 707.85 | 2.72 | 2.72 |
| 255.79 | 2.98 | 2.98 |
| 255.79 | 2.98 | 2.98 |
| 328.29 | 3.37 | 3.37 |
| 328.23 | 2.39 | 2.39 |
| 280.28 | 1.64 | 1.64 |
| 203.67 | 0.86 | 0.86 |
| 255.79 | 2.00 | 2.00 |
| 455.19 | 4.04 | 4.04 |
| 350.26 | 2.72 | 2.72 |
| 321.80 | 2.85 | 2.85 |
| 345.91 | 4.20 | 4.20 |
| 285.77 | 1.94 | 1.94 |
| 312.25 | 2.91 | 2.91 |
| 365.90 | 3.26 | 3.26 |
| 376.29 | 3.27 | 3.27 |
| 590.58 | 2.32 | 2.32 |
| 333.29 | 0.35 | 0.35 |
| 364.24 | 2.56 | 2.56 |
| 259.38 | 2.47 | 2.47 |
| 273.40 | 2.77 | 2.77 |
| 363.44 | 2.77 | 2.77 |
| 484.02 | 4.12 | 4.12 |
| 282.39 | 2.42 | 2.42 |
| 281.78 | 2.38 | 2.38 |
| 338.27 | 3.23 | 3.23 |
| 252.79 | 3.01 | 3.01 |
| 382.86 | 3.04 | 3.04 |
| 413.95 | 2.91 | 2.91 |
| 322.45 | 3.18 | 3.18 |
| 288.78 | 2.45 | 2.45 |
| 405.54 | 2.19 | 2.19 |
| 270.34 | 1.50 | 1.50 |
| 412.02 | 3.19 | 3.19 |
| 268.36 | 2.11 | 2.11 |
| 391.90 | 1.85 | 1.85 |
| 381.43 | 2.11 | 2.11 |
| 376.41 | 2.25 | 2.25 |
| 495.60 | 3.27 | 3.27 |
| 429.55 | 1.63 | 1.63 |
| 436.53 | 4.49 | 4.49 |
| 252.74 | 2.70 | 2.70 |
| 461.58 | 1.27 | 1.27 |
| 379.26 | 2.28 | 2.28 |
| 398.33 | 2.43 | 2.43 |
| 439.26 | 3.00 | 3.00 |
| 339.48 | 3.77 | 3.77 |
| 299.33 | 1.71 | 1.71 |
| 598.74 | 6.62 | 6.62 |
| 750.71 | 3.19 | 3.19 |
| 477.58 | 0.98 | 0.98 |
| 323.23 | 3.11 | 3.11 |
| 286.81 | 3.66 | 3.66 |
| 268.40 | 3.02 | 3.02 |
| 496.03 | 1.92 | 1.92 |
| 401.51 | 4.27 | 4.27 |
| 329.79 | 2.77 | 2.77 |
| 496.61 | 3.57 | 3.57 |
| 436.97 | 2.35 | 2.35 |
| 390.39 | 2.25 | 2.25 |
| 223.63 | 0.23 | 0.23 |
| 359.47 | 3.98 | 3.98 |
| 378.82 | 2.04 | 2.04 |
| 454.96 | 4.29 | 4.29 |
| 375.40 | 2.30 | 2.30 |
| 267.38 | 2.71 | 2.71 |
| 314.35 | 1.23 | 1.23 |
| 679.80 | 2.08 | 2.08 |
| 378.36 | 2.38 | 2.38 |
| 420.42 | 2.25 | 2.25 |
| 389.46 | 4.41 | 4.41 |
| 312.42 | 2.42 | 2.42 |
| 321.34 | 3.88 | 3.88 |
| 314.39 | 1.82 | 1.82 |
| 333.23 | 2.56 | 2.56 |
| 406.44 | 1.47 | 1.47 |
| 254.34 | 1.80 | 1.80 |
| 304.78 | 2.89 | 2.89 |
| 519.62 | 2.67 | 2.67 |
| 373.88 | 4.91 | 4.91 |
| 442.36 | 3.56 | 3.56 |
| 415.54 | 4.58 | 4.58 |
| 354.43 | 3.56 | 3.56 |
| 292.34 | 1.69 | 1.69 |
| 366.85 | 4.45 | 4.45 |
| 365.47 | 4.26 | 4.26 |
| 415.45 | 4.44 | 4.44 |
| 430.57 | 2.78 | 2.78 |
| 347.46 | 2.40 | 2.40 |
| 337.28 | 0.09 | 0.09 |
| 314.39 | 1.82 | 1.82 |
| 368.44 | 2.22 | 2.22 |
| 382.45 | 3.29 | 3.29 |
| 447.44 | 2.06 | 2.06 |
| 390.39 | 2.25 | 2.25 |
| 364.45 | 2.00 | 2.00 |
| 494.53 | 1.14 | 1.14 |
| 445.59 | 2.18 | 2.18 |
| 338.37 | 1.36 | 1.36 |
| 374.48 | 3.21 | 3.21 |
| 397.91 | 3.25 | 3.25 |
| 361.46 | 1.88 | 1.88 |
| 291.78 | 2.38 | 2.38 |
| 394.45 | 1.53 | 1.53 |
| 413.26 | 3.11 | 3.11 |
| 388.42 | 2.80 | 2.80 |
| 377.92 | 2.26 | 2.26 |
| 403.44 | 5.27 | 5.27 |
| 392.28 | 4.35 | 4.35 |
| 375.90 | 2.25 | 2.25 |
| 309.37 | 3.83 | 3.83 |
| 293.82 | 3.12 | 3.12 |
| 282.39 | 2.42 | 2.42 |
| 288.78 | 2.45 | 2.45 |
| 272.33 | 1.94 | 1.94 |
| 482.63 | 3.58 | 3.58 |
| 292.43 | 3.91 | 3.91 |
| 245.78 | 1.31 | 1.31 |
| 486.61 | 2.62 | 2.62 |
| 300.36 | 2.25 | 2.25 |
| 376.93 | 2.87 | 2.87 |
| 429.86 | 2.59 | 2.59 |
| 347.87 | 2.79 | 2.79 |
| 378.36 | 2.38 | 2.38 |
| 366.42 | 2.47 | 2.47 |
| 409.93 | 3.48 | 3.48 |
| 474.96 | 4.66 | 4.66 |
| 388.47 | 3.63 | 3.63 |
| 286.40 | 2.71 | 2.71 |
| 314.39 | 1.82 | 1.82 |
| 406.48 | 3.83 | 3.83 |
| 272.33 | 1.94 | 1.94 |
| 482.63 | 6.44 | 6.44 |
| 401.52 | 2.86 | 2.86 |
| 328.42 | 2.21 | 2.21 |
| 353.44 | 3.70 | 3.70 |
| 357.93 | 4.59 | 4.59 |
| 333.46 | 1.84 | 1.84 |
| 407.92 | 2.59 | 2.59 |
| 369.51 | 3.78 | 3.78 |
| 733.78 | 2.08 | 2.08 |
| 439.26 | 3.00 | 3.00 |
| 493.94 | -1.07 | -1.07 |
| 371.46 | 3.38 | 3.38 |
| 441.48 | 3.42 | 3.42 |
| 348.87 | 3.25 | 3.25 |
| 288.39 | 2.86 | 2.86 |
| 428.49 | 3.58 | 3.58 |
| 302.17 | 1.41 | 1.41 |
| 367.32 | 3.92 | 3.92 |
| 371.41 | 2.71 | 2.71 |
| 391.45 | 3.71 | 3.71 |
| 431.54 | 2.87 | 2.87 |
| 258.32 | 1.70 | 1.70 |
| 750.71 | 3.19 | 3.19 |
| 404.51 | 3.34 | 3.34 |
| 293.37 | 2.28 | 2.28 |
| 335.41 | 4.37 | 4.37 |
| 406.46 | 2.71 | 2.71 |
| 339.44 | 1.92 | 1.92 |
| 374.39 | 2.55 | 2.55 |
| 396.89 | 2.57 | 2.57 |
| 369.47 | 2.24 | 2.24 |
| 390.44 | 3.13 | 3.13 |
| 407.92 | 3.29 | 3.29 |
| 344.41 | 2.64 | 2.64 |
| 400.50 | 2.58 | 2.58 |
| 359.47 | 3.98 | 3.98 |
| 404.42 | 2.64 | 2.64 |
| 679.80 | 2.08 | 2.08 |
| 284.36 | 2.55 | 2.55 |
| 227.69 | 1.47 | 1.47 |
| 479.62 | 3.81 | 3.81 |
| 416.57 | 3.78 | 3.78 |
| 305.40 | 1.96 | 1.96 |
| 399.51 | 3.98 | 3.98 |
| 398.55 | 2.80 | 2.80 |
| 749.95 | 4.30 | 4.30 |
| 297.36 | 2.13 | 2.13 |
| 440.45 | 3.40 | 3.40 |
| 379.89 | 1.65 | 1.65 |
| 334.37 | 1.28 | 1.28 |
| 381.52 | 1.66 | 1.66 |
| 313.40 | 2.42 | 2.42 |
| 360.41 | 2.26 | 2.26 |
| 440.59 | 1.52 | 1.52 |
| 273.76 | 1.88 | 1.88 |
| 287.79 | 3.06 | 3.06 |
| 382.46 | 1.67 | 1.67 |
| 403.95 | 4.20 | 4.20 |
| 458.57 | 3.22 | 3.22 |
| 417.54 | 1.40 | 1.40 |
| 376.50 | 3.71 | 3.71 |
| 322.33 | 2.82 | 2.82 |
| 245.15 | 2.71 | 2.71 |
| 464.57 | 0.89 | 0.89 |
| 416.57 | 4.06 | 4.06 |
| 428.58 | 4.06 | 4.06 |
| 385.46 | 1.85 | 1.85 |
| 446.56 | 3.22 | 3.22 |
| 353.49 | 4.36 | 4.36 |
| 380.49 | 3.00 | 3.00 |
| 343.38 | 3.18 | 3.18 |
| 375.41 | 2.36 | 2.36 |
| 181.19 | 0.50 | 0.50 |
| 290.32 | 2.08 | 2.08 |
| 411.46 | 3.22 | 3.22 |
| 284.26 | 1.58 | 1.58 |
| 316.36 | 4.00 | 4.00 |
| 402.45 | 2.95 | 2.95 |
| 350.38 | 3.32 | 3.32 |
| 331.83 | 3.72 | 3.72 |