ID: ALA2114797
Type: Functional
Description: PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory)
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA2114797
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
391.56 | 6.86 | 6.86 |
146.14 | 1.79 | 1.79 |
248.72 | 2.52 | 2.52 |
300.44 | 5.60 | 5.60 |
387.52 | 5.70 | 5.70 |
853.92 | 3.74 | 3.74 |
406.91 | 6.61 | 6.61 |
404.55 | 4.20 | 4.20 |
184.11 | 1.21 | 1.21 |
308.38 | 3.79 | 3.79 |
314.47 | 4.72 | 4.72 |
88.11 | 0.57 | 0.57 |
124.14 | 1.40 | 1.40 |
399.44 | 2.87 | 2.87 |
144.21 | 2.29 | 2.29 |
268.36 | 3.05 | 3.05 |
352.77 | 2.81 | 2.81 |
301.34 | 3.60 | 3.60 |
300.31 | 3.87 | 3.87 |
354.49 | 6.50 | 6.50 |
215.69 | 1.78 | 1.78 |
184.24 | 2.52 | 2.52 |
78.11 | 1.69 | 1.69 |
222.24 | 3.46 | 3.46 |
381.38 | 3.51 | 3.51 |
303.15 | 3.91 | 3.91 |
163.20 | -0.49 | -0.49 |
201.25 | 2.69 | 2.69 |
392.47 | 1.90 | 1.90 |
358.43 | 1.77 | 1.77 |
272.39 | 3.61 | 3.61 |
143.19 | 2.42 | 2.42 |
320.43 | 5.17 | 5.17 |
296.41 | 3.61 | 3.61 |
368.39 | 3.37 | 3.37 |
158.28 | 3.12 | 3.12 |
386.53 | 4.66 | 4.66 |
125.17 | 1.65 | 1.65 |
331.20 | 4.07 | 4.07 |
256.13 | 3.14 | 3.14 |
335.28 | 4.15 | 4.15 |
118.18 | 0.80 | 0.80 |
356.06 | 5.86 | 5.86 |
563.65 | 6.00 | 6.00 |
482.44 | 2.36 | 2.36 |
136.20 | 1.33 | 1.33 |
505.46 | 4.18 | 4.18 |
272.39 | 3.61 | 3.61 |
372.81 | 4.41 | 4.41 |
276.21 | 3.21 | 3.21 |
310.48 | 5.06 | 5.06 |
180.21 | 2.78 | 2.78 |
285.34 | 3.00 | 3.00 |
268.36 | 5.55 | 5.55 |
169.23 | 2.94 | 2.94 |
380.91 | 4.48 | 4.48 |
218.26 | 0.54 | 0.54 |
151.19 | 1.59 | 1.59 |
181.45 | 3.65 | 3.65 |
153.82 | 2.55 | 2.55 |
41.05 | 0.53 | 0.53 |
518.56 | 6.38 | 6.38 |
346.37 | 1.78 | 1.78 |
410.51 | 1.52 | 1.52 |
368.48 | 4.21 | 4.21 |
466.56 | 2.88 | 2.88 |
173.26 | 3.29 | 3.29 |
481.34 | 4.76 | 4.76 |
329.44 | 4.67 | 4.67 |
407.99 | 4.46 | 4.46 |
286.46 | 5.51 | 5.51 |
422.87 | 6.66 | 6.66 |
246.40 | 4.57 | 4.57 |
108.14 | 0.85 | 0.85 |
191.19 | 1.74 | 1.74 |
284.44 | 5.72 | 5.72 |
225.29 | 4.30 | 4.30 |
197.24 | 3.68 | 3.68 |
231.29 | 2.95 | 2.95 |
267.16 | 3.75 | 3.75 |
193.25 | 3.58 | 3.58 |
228.29 | 5.15 | 5.15 |
330.47 | 3.84 | 3.84 |
223.23 | 2.04 | 2.04 |
190.27 | 1.47 | 1.47 |
290.32 | 2.57 | 2.57 |
256.35 | 5.76 | 5.76 |
180.23 | 1.89 | 1.89 |
227.05 | 2.75 | 2.75 |
510.06 | 6.08 | 6.08 |
213.66 | 3.30 | 3.30 |
168.15 | 1.19 | 1.19 |
198.13 | 1.52 | 1.52 |
341.84 | 3.74 | 3.74 |
359.92 | 4.84 | 4.84 |
346.47 | 2.67 | 2.67 |
344.50 | 4.84 | 4.84 |
384.45 | 6.46 | 6.46 |
105.14 | -1.44 | -1.44 |
281.35 | 1.04 | 1.04 |
240.44 | 2.06 | 2.06 |
663.90 | 4.75 | 4.75 |
326.23 | 3.99 | 3.99 |
291.78 | 3.34 | 3.34 |
416.95 | 4.61 | 4.61 |
353.42 | 4.02 | 4.02 |
491.07 | 5.09 | 5.09 |
297.19 | 4.13 | 4.13 |
137.37 | 2.28 | 2.28 |
291.27 | 3.27 | 3.27 |
183.12 | 1.09 | 1.09 |
186.10 | 1.64 | 1.64 |
199.21 | 2.85 | 2.85 |
218.17 | 2.66 | 2.66 |
223.23 | 3.90 | 3.90 |
117.11 | 0.07 | 0.07 |
220.98 | 2.68 | 2.68 |
212.25 | 3.33 | 3.33 |
219.29 | 4.58 | 4.58 |
217.31 | 3.69 | 3.69 |
421.50 | 5.03 | 5.03 |
320.05 | 5.93 | 5.93 |
409.78 | 5.68 | 5.68 |
345.65 | 5.21 | 5.21 |
354.49 | 6.50 | 6.50 |
416.58 | 4.85 | 4.85 |
302.46 | 4.27 | 4.27 |
416.30 | 6.18 | 6.18 |
307.29 | 2.23 | 2.23 |
313.35 | 3.10 | 3.10 |
210.28 | 2.19 | 2.19 |
548.63 | 3.48 | 3.48 |
461.56 | 5.86 | 5.86 |
392.47 | 1.90 | 1.90 |
130.08 | -0.80 | -0.80 |
307.10 | -1.06 | -1.06 |
362.47 | 1.78 | 1.78 |
336.45 | 3.33 | 3.33 |
364.94 | 5.24 | 5.24 |
356.06 | 5.13 | 5.13 |
485.80 | 6.53 | 6.53 |
564.69 | 7.29 | 7.29 |
352.48 | 4.45 | 4.45 |
330.82 | 3.93 | 3.93 |
149.15 | 1.93 | 1.93 |
403.39 | 4.09 | 4.09 |
300.59 | 2.91 | 2.91 |
337.46 | 4.22 | 4.22 |
125.15 | -1.17 | -1.17 |
143.57 | 1.63 | 1.63 |
244.21 | -3.17 | -3.17 |
228.25 | 2.82 | 2.82 |
360.45 | 1.99 | 1.99 |
346.34 | 2.18 | 2.18 |
312.45 | 4.64 | 4.64 |
362.77 | 4.43 | 4.43 |
391.29 | 6.11 | 6.11 |
152.22 | 1.34 | 1.34 |
225.29 | 4.17 | 4.17 |
312.45 | 4.64 | 4.64 |
377.07 | 3.66 | 3.66 |
293.75 | 3.12 | 3.12 |
207.02 | 2.48 | 2.48 |
323.31 | 4.74 | 4.74 |
307.82 | 3.34 | 3.34 |
434.97 | 1.49 | 1.49 |
494.48 | 6.38 | 6.38 |
340.51 | 5.90 | 5.90 |
404.82 | ||
328.50 | 6.08 | 6.08 |
248.19 | 2.87 | 2.87 |
225.29 | 3.41 | 3.41 |
416.51 | ||
490.64 | 4.62 | 4.62 |
249.10 | 3.02 | 3.02 |
275.53 | 3.58 | 3.58 |
408.92 | 2.17 | 2.17 |
287.17 | 4.56 | 4.56 |
385.48 | ||
367.04 | ||
142.11 | 0.47 | 0.47 |
1229.32 | ||
295.77 | 2.92 | 2.92 |
419.91 | 6.68 | 6.68 |
349.43 | 5.27 | 5.27 |
720.72 | -0.20 | -0.20 |
230.31 | 5.02 | 5.02 |
265.91 | 4.04 | 4.04 |
376.67 | 4.60 | 4.60 |
320.05 | 5.93 | 5.93 |
220.26 | 2.18 | 2.18 |
345.75 | 4.56 | 4.56 |
326.29 | 5.33 | 5.33 |
355.33 | 4.89 | 4.89 |
266.09 | -1.08 | -1.08 |
342.23 | 3.65 | 3.65 |
373.91 | 2.50 | 2.50 |
142.59 | 1.50 | 1.50 |
197.24 | 3.80 | 3.80 |
194.26 | 2.28 | 2.28 |
274.27 | 2.27 | 2.27 |
230.26 | 2.55 | 2.55 |
300.31 | 3.78 | 3.78 |
345.23 | 4.22 | 4.22 |
225.31 | 2.74 | 2.74 |
343.21 | 5.31 | 5.31 |
294.39 | 3.53 | 3.53 |
258.27 | 2.83 | 2.83 |
317.71 | 0.61 | 0.61 |
380.87 | 5.87 | 5.87 |
218.14 | ||
192.52 | 1.40 | 1.40 |
249.71 | 2.66 | 2.66 |
444.70 | 5.80 | 5.80 |
338.44 | 3.72 | 3.72 |
361.49 | 5.77 | 5.77 |
598.09 | 6.56 | 6.56 |
350.30 | 3.73 | 3.73 |
138.17 | 1.06 | 1.06 |
121.18 | 1.89 | 1.89 |
235.31 | 2.62 | 2.62 |
391.56 | 6.86 | 6.86 |
311.41 | 3.49 | 3.49 |
229.41 | 4.48 | 4.48 |
191.14 | -1.46 | -1.46 |
488.59 | 5.20 | 5.20 |
120.15 | -0.36 | -0.36 |
390.56 | 6.43 | 6.43 |
281.31 | 3.72 | 3.72 |
295.34 | 4.01 | 4.01 |
333.27 | 3.92 | 3.92 |
429.60 | 5.41 | 5.41 |
248.71 | 2.97 | 2.97 |
395.26 | 4.13 | 4.13 |
122.17 | 1.16 | 1.16 |
214.22 | 3.34 | 3.34 |
272.26 | 2.86 | 2.86 |
260.34 | 5.17 | 5.17 |
336.74 | ||
287.17 | 3.83 | 3.83 |
252.32 | 5.64 | 5.64 |
320.40 | 3.10 | 3.10 |
348.96 | 5.45 | 5.45 |
278.35 | 6.30 | 6.30 |
194.27 | 2.85 | 2.85 |
206.33 | 3.90 | 3.90 |
148.12 | 1.00 | 1.00 |
253.37 | 2.61 | 2.61 |
294.18 | ||
141.60 | 2.23 | 2.23 |
271.50 | ||
164.25 | 1.82 | 1.82 |
211.69 | 2.67 | 2.67 |
341.50 | 4.26 | 4.26 |
217.89 | 1.14 | 1.14 |
211.65 | 2.07 | 2.07 |
199.99 | -0.66 | -0.66 |
220.36 | 4.11 | 4.11 |
252.04 | ||
359.57 | 5.73 | 5.73 |
340.38 | 4.08 | 4.08 |
184.65 | 2.53 | 2.53 |
237.26 | 2.35 | 2.35 |
350.48 | 3.92 | 3.92 |
287.23 | 3.41 | 3.41 |
318.37 | 1.62 | 1.62 |
151.62 | 0.45 | 0.45 |
266.53 | ||
198.22 | 3.61 | 3.61 |
226.32 | 4.25 | 4.25 |
616.79 | 3.41 | 3.41 |
258.28 | 3.63 | 3.63 |
183.32 | ||
428.48 | 1.62 | 1.62 |
189.64 | 1.29 | 1.29 |
273.29 | 3.40 | 3.40 |
296.28 | 3.31 | 3.31 |
241.29 | 2.67 | 2.67 |
182.13 | 1.81 | 1.81 |
252.31 | 3.09 | 3.09 |
302.32 | 0.49 | 0.49 |
195.22 | 1.88 | 1.88 |
178.26 | 2.50 | 2.50 |
546.81 | 11.25 | 11.25 |
276.29 | 2.19 | 2.19 |
305.83 | 0.76 | 0.76 |
150.22 | 2.71 | 2.71 |
248.72 | 3.27 | 3.27 |
159.62 | 1.28 | 1.28 |
130.20 | 1.37 | 1.37 |
358.55 | 6.46 | 6.46 |
251.24 | 1.64 | 1.64 |
367.82 | 4.24 | 4.24 |
241.73 | 0.24 | 0.24 |
552.58 | 5.40 | 5.40 |
398.48 | 4.59 | 4.59 |
330.21 | 1.69 | 1.69 |
219.29 | 4.58 | 4.58 |
927.02 | 4.39 | 4.39 |
268.40 | 5.28 | 5.28 |
213.35 | 3.27 | 3.27 |
188.01 | 2.96 | 2.96 |
411.80 | 5.38 | 5.38 |
337.42 | 3.93 | 3.93 |
150.18 | 2.15 | 2.15 |
275.17 | 2.39 | 2.39 |
251.08 | ||
284.44 | 5.72 | 5.72 |
505.21 | 6.49 | 6.49 |
368.37 | 6.26 | 6.26 |
198.22 | 3.83 | 3.83 |
410.45 | 7.18 | 7.18 |
323.83 | 3.80 | 3.80 |
326.05 | 3.82 | 3.82 |
303.84 | 3.23 | 3.23 |
269.34 | 4.03 | 4.03 |
384.49 | 5.01 | 5.01 |
374.40 | 4.70 | 4.70 |
330.17 | 2.88 | 2.88 |
324.79 | 2.04 | 2.04 |
421.73 | 5.34 | 5.34 |
285.22 | 3.13 | 3.13 |
403.89 | 2.80 | 2.80 |
340.06 | 5.47 | 5.47 |
474.82 | 2.87 | 2.87 |
428.12 | 4.40 | 4.40 |
639.83 | 5.73 | 5.73 |
407.62 | 5.46 | 5.46 |
308.14 | 5.47 | 5.47 |
326.23 | 3.99 | 3.99 |
434.29 | 6.32 | 6.32 |
361.70 | 5.46 | 5.46 |
302.41 | 4.00 | 4.00 |
665.01 | 7.46 | 7.46 |
228.29 | 5.15 | 5.15 |
380.91 | 4.48 | 4.48 |
290.83 | 3.64 | 3.64 |
275.39 | 3.01 | 3.01 |
281.31 | 2.34 | 2.34 |
300.40 | 3.45 | 3.45 |
342.39 | 3.49 | 3.49 |
271.36 | 3.48 | 3.48 |
294.31 | 3.62 | 3.62 |
207.11 | 2.32 | 2.32 |
465.09 | 5.99 | 5.99 |
241.87 | 0.48 | 0.48 |
313.75 | 3.19 | 3.19 |
914.14 | 5.52 | 5.52 |
318.33 | 4.13 | 4.13 |
336.83 | 4.03 | 4.03 |
241.36 | 2.23 | 2.23 |
303.67 | 2.95 | 2.95 |
409.78 | 5.68 | 5.68 |
359.42 | 5.18 | 5.18 |
368.42 | 4.89 | 4.89 |
367.25 | 4.39 | 4.39 |
345.40 | 3.89 | 3.89 |
321.38 | 4.72 | 4.72 |
319.84 | 3.34 | 3.34 |
296.56 | 3.26 | 3.26 |
1008.26 | 5.60 | 5.60 |
422.03 | 2.92 | 2.92 |
304.67 | 4.84 | 4.84 |
396.38 | 4.52 | 4.52 |
345.39 | 2.78 | 2.78 |
380.78 | 3.65 | 3.65 |
302.41 | 4.00 | 4.00 |
542.71 | 4.92 | 4.92 |
377.07 | 3.66 | 3.66 |
377.07 | 3.66 | 3.66 |
385.18 | ||
406.93 | 3.69 | 3.69 |
206.28 | 2.76 | 2.76 |
221.28 | 2.07 | 2.07 |
419.91 | 6.68 | 6.68 |
247.68 | 3.30 | 3.30 |
240.22 | 2.72 | 2.72 |
191.23 | 1.91 | 1.91 |
349.07 | 3.52 | 3.52 |
281.09 | 1.91 | 1.91 |
214.35 | 4.08 | 4.08 |
411.33 | 5.94 | 5.94 |
397.52 | 3.77 | 3.77 |
351.85 | ||
502.92 | 7.40 | 7.40 |
333.86 | 3.86 | 3.86 |
293.80 | 3.12 | 3.12 |
314.22 | 3.66 | 3.66 |
391.29 | 6.11 | 6.11 |
315.40 | ||
314.52 | 6.69 | 6.69 |
214.26 | 3.14 | 3.14 |
393.85 | 3.88 | 3.88 |
232.33 | 3.39 | 3.39 |
527.84 | 4.09 | 4.09 |
458.83 | 4.56 | 4.56 |
401.42 | 5.24 | 5.24 |
389.32 | 4.45 | 4.45 |
274.40 | 4.25 | 4.25 |
238.36 | 3.56 | 3.56 |
274.10 | 2.80 | 2.80 |
260.68 | 2.64 | 2.64 |
288.78 | 3.58 | 3.58 |
352.89 | 4.98 | 4.98 |
449.86 | 6.54 | 6.54 |
283.36 | 3.83 | 3.83 |
376.50 | 6.37 | 6.37 |
350.46 | 5.76 | 5.76 |
291.78 | 2.87 | 2.87 |
285.37 | 2.54 | 2.54 |
301.30 | 2.49 | 2.49 |
372.15 | 4.24 | 4.24 |
293.75 | 3.12 | 3.12 |
381.46 | 3.66 | 3.66 |
377.07 | 3.66 | 3.66 |
332.40 | 4.02 | 4.02 |
226.36 | 2.58 | 2.58 |
253.20 | ||
293.75 | 3.12 | 3.12 |
1732.15 |