Basic Information
ID: ALA2114816
Type: Functional
Description: PubChem BioAssay. Fluorescence polarization aasay to screen for inhibitors that compete for the binding of FadD28 to a bisubstrate Measured in Biochemical System Using Plate Reader - 2147-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory)
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA2114816
AC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 252.32 | 2.74 | 2.74 |
| 325.54 | 5.13 | 5.13 |
| 394.32 | 4.13 | 4.13 |
| 256.21 | 1.58 | 1.58 |
| 359.73 | 2.43 | 2.43 |
| 394.37 | 0.43 | 0.43 |
| 208.26 | 3.33 | 3.33 |
| 258.23 | 2.32 | 2.32 |
| 294.35 | 4.25 | 4.25 |
| 416.55 | 3.73 | 3.73 |
| 326.35 | 3.59 | 3.59 |
| 444.45 | 3.02 | 3.02 |
| 301.52 | 4.15 | 4.15 |
| 412.44 | 3.96 | 3.96 |
| 278.26 | 2.85 | 2.85 |
| 417.51 | 4.73 | 4.73 |
| 290.75 | 1.76 | 1.76 |
| 514.44 | 0.88 | 0.88 |
| 482.49 | 5.55 | 5.55 |
| 410.43 | 5.23 | 5.23 |
| 404.43 | 2.83 | 2.83 |
| 436.56 | 2.45 | 2.45 |
| 422.51 | 4.24 | 4.24 |
| 310.28 | 3.60 | 3.60 |
| 370.33 | 5.71 | 5.71 |
| 392.48 | 4.24 | 4.24 |
| 328.37 | 3.63 | 3.63 |
| 323.35 | 2.87 | 2.87 |
| 470.34 | 3.78 | 3.78 |
| 411.50 | 3.87 | 3.87 |
| 444.54 | 2.43 | 2.43 |
| 415.24 | 2.86 | 2.86 |
| 492.56 | 3.01 | 3.01 |
| 358.51 | 3.87 | 3.87 |
| 357.45 | 3.22 | 3.22 |
| 275.31 | 3.06 | 3.06 |
| 705.66 | 5.71 | 5.71 |
| 413.41 | 3.28 | 3.28 |
| 503.61 | 2.82 | 2.82 |
| 374.40 | 4.25 | 4.25 |
| 288.39 | 4.12 | 4.12 |
| 454.62 | 4.48 | 4.48 |
| 383.47 | 3.63 | 3.63 |
| 285.37 | 2.82 | 2.82 |
| 433.52 | 3.55 | 3.55 |
| 382.85 | 4.36 | 4.36 |
| 324.52 | 4.56 | 4.56 |
| 469.64 | 4.65 | 4.65 |
| 377.47 | 4.12 | 4.12 |
| 370.41 | 4.87 | 4.87 |
| 434.48 | 4.18 | 4.18 |
| 444.45 | 3.02 | 3.02 |
| 434.52 | 3.38 | 3.38 |
| 357.80 | 5.69 | 5.69 |
| 450.58 | 2.80 | 2.80 |
| 449.92 | 3.44 | 3.44 |
| 862.75 | -1.10 | -1.10 |
| 408.91 | 3.06 | 3.06 |
| 434.52 | 3.38 | 3.38 |
| 327.45 | 3.80 | 3.80 |
| 477.90 | 4.11 | 4.11 |
| 487.35 | 3.41 | 3.41 |
| 445.52 | 2.95 | 2.95 |
| 334.81 | 3.02 | 3.02 |
| 488.57 | 1.89 | 1.89 |
| 361.83 | 4.75 | 4.75 |
| 493.61 | 4.14 | 4.14 |
| 372.43 | 2.64 | 2.64 |
| 298.41 | 3.79 | 3.79 |
| 428.44 | 2.72 | 2.72 |
| 390.38 | 2.18 | 2.18 |
| 395.42 | 2.63 | 2.63 |
| 391.34 | 3.02 | 3.02 |
| 352.25 | 4.04 | 4.04 |
| 443.53 | 2.77 | 2.77 |
| 431.54 | 4.42 | 4.42 |
| 424.54 | 2.32 | 2.32 |
| 386.41 | 1.31 | 1.31 |
| 430.35 | 3.98 | 3.98 |
| 304.37 | 2.21 | 2.21 |
| 400.43 | 5.11 | 5.11 |
| 444.58 | 4.36 | 4.36 |
| 318.36 | 1.75 | 1.75 |
| 298.39 | 4.64 | 4.64 |
| 268.68 | 2.19 | 2.19 |
| 368.39 | 3.04 | 3.04 |
| 394.46 | 3.24 | 3.24 |
| 343.45 | 4.48 | 4.48 |
| 439.54 | 4.87 | 4.87 |
| 371.46 | 2.99 | 2.99 |
| 265.31 | 3.40 | 3.40 |
| 438.98 | 6.00 | 6.00 |
| 466.49 | 5.79 | 5.79 |
| 332.36 | 4.38 | 4.38 |
| 422.82 | 4.07 | 4.07 |
| 361.45 | 3.36 | 3.36 |
| 267.12 | ||
| 367.45 | 3.56 | 3.56 |
| 461.50 | 4.16 | 4.16 |
| 410.74 | 4.98 | 4.98 |
| 534.66 | 5.33 | 5.33 |
| 344.28 | 2.47 | 2.47 |
| 335.81 | 4.23 | 4.23 |
| 490.92 | 3.80 | 3.80 |
| 333.38 | 4.11 | 4.11 |
| 458.52 | 2.54 | 2.54 |
| 362.41 | 1.68 | 1.68 |
| 469.03 | 3.33 | 3.33 |
| 392.48 | 4.29 | 4.29 |
| 366.49 | 3.72 | 3.72 |
| 372.43 | 2.64 | 2.64 |
| 489.55 | 4.78 | 4.78 |
| 367.32 | 1.41 | 1.41 |
| 404.17 | 3.53 | 3.53 |
| 301.31 | 2.57 | 2.57 |
| 476.65 | 4.67 | 4.67 |
| 455.52 | 3.05 | 3.05 |
| 462.86 | 6.02 | 6.02 |
| 407.81 | 3.93 | 3.93 |
| 365.46 | 3.80 | 3.80 |
| 495.50 | 3.08 | 3.08 |
| 352.41 | 4.86 | 4.86 |
| 343.18 | 2.91 | 2.91 |
| 245.27 | 1.15 | 1.15 |
| 399.38 | 2.98 | 2.98 |
| 398.44 | 3.38 | 3.38 |
| 363.38 | 2.72 | 2.72 |
| 482.60 | 4.72 | 4.72 |
| 467.53 | 2.36 | 2.36 |
| 349.39 | 0.94 | 0.94 |
| 423.65 | 3.28 | 3.28 |
| 380.45 | 2.96 | 2.96 |
| 430.53 | 3.36 | 3.36 |
| 440.59 | 4.17 | 4.17 |
| 443.24 | 5.05 | 5.05 |
| 517.63 | 3.13 | 3.13 |
| 320.37 | 3.83 | 3.83 |
| 311.18 | 3.88 | 3.88 |
| 324.34 | 1.57 | 1.57 |
| 396.45 | 3.05 | 3.05 |
| 344.41 | 3.74 | 3.74 |
| 453.45 | 5.79 | 5.79 |
| 369.33 | 2.08 | 2.08 |
| 433.51 | 4.40 | 4.40 |
| 380.45 | 3.11 | 3.11 |
| 431.47 | 2.03 | 2.03 |
| 369.33 | 2.08 | 2.08 |
| 384.49 | 3.16 | 3.16 |
| 304.46 | 4.70 | 4.70 |
| 342.42 | 2.83 | 2.83 |
| 423.49 | 5.21 | 5.21 |
| 380.29 | 3.65 | 3.65 |
| 345.45 | 3.24 | 3.24 |
| 445.43 | 3.48 | 3.48 |
| 438.44 | 4.01 | 4.01 |
| 463.56 | 6.15 | 6.15 |
| 393.45 | 1.67 | 1.67 |
| 432.44 | 2.43 | 2.43 |
| 422.47 | 3.64 | 3.64 |
| 432.55 | 3.35 | 3.35 |
| 355.32 | 4.79 | 4.79 |
| 426.56 | 5.26 | 5.26 |
| 386.53 | 2.95 | 2.95 |
| 345.38 | 2.80 | 2.80 |
| 402.45 | 2.65 | 2.65 |
| 430.58 | 4.04 | 4.04 |
| 290.32 | 3.64 | 3.64 |
| 399.43 | 2.77 | 2.77 |
| 354.36 | 1.98 | 1.98 |
| 505.87 | 5.49 | 5.49 |
| 356.04 | 5.29 | 5.29 |
| 341.29 | 4.04 | 4.04 |
| 500.52 | 2.73 | 2.73 |
| 396.51 | 5.11 | 5.11 |
| 304.35 | 3.53 | 3.53 |
| 353.41 | 3.09 | 3.09 |
| 429.53 | 3.12 | 3.12 |
| 372.43 | 2.64 | 2.64 |
| 419.53 | 4.25 | 4.25 |
| 455.00 | 3.02 | 3.02 |
| 493.61 | 5.01 | 5.01 |
| 452.15 | 4.67 | 4.67 |
| 302.34 | 2.59 | 2.59 |
| 343.38 | 2.56 | 2.56 |
| 419.46 | 1.76 | 1.76 |
| 394.39 | 1.18 | 1.18 |
| 404.43 | 3.06 | 3.06 |
| 387.44 | 3.31 | 3.31 |
| 314.30 | 2.81 | 2.81 |
| 412.54 | 2.69 | 2.69 |
| 361.40 | 4.81 | 4.81 |
| 485.50 | 3.80 | 3.80 |
| 322.36 | 3.05 | 3.05 |
| 380.88 | 4.01 | 4.01 |
| 487.33 | 4.43 | 4.43 |
| 337.57 | 5.56 | 5.56 |
| 294.29 | 1.56 | 1.56 |
| 414.55 | 3.26 | 3.26 |
| 298.30 | 2.24 | 2.24 |
| 372.43 | 2.64 | 2.64 |
| 257.32 | 2.92 | 2.92 |
| 476.61 | 3.25 | 3.25 |
| 416.50 | 3.05 | 3.05 |
| 410.43 | 3.81 | 3.81 |
| 195.25 | 1.59 | 1.59 |
| 268.73 | 3.92 | 3.92 |
| 490.54 | 5.25 | 5.25 |
| 323.47 | 4.54 | 4.54 |
| 508.01 | 5.19 | 5.19 |
| 442.52 | 4.66 | 4.66 |
| 435.99 | 4.76 | 4.76 |
| 264.40 | 4.18 | 4.18 |
| 472.50 | 3.63 | 3.63 |
| 444.45 | 3.02 | 3.02 |
| 424.24 | 3.84 | 3.84 |
| 406.47 | 4.74 | 4.74 |
| 394.48 | 3.53 | 3.53 |
| 439.41 | 4.49 | 4.49 |
| 323.35 | 3.48 | 3.48 |
| 443.53 | 2.17 | 2.17 |
| 367.88 | 3.88 | 3.88 |
| 356.41 | 2.11 | 2.11 |
| 286.38 | 3.85 | 3.85 |
| 455.94 | 5.63 | 5.63 |
| 440.29 | 5.29 | 5.29 |
| 423.28 | 4.37 | 4.37 |
| 415.61 | 2.77 | 2.77 |
| 459.46 | 3.79 | 3.79 |
| 489.55 | 4.78 | 4.78 |
| 433.48 | 2.53 | 2.53 |
| 388.49 | 1.81 | 1.81 |
| 405.50 | 3.94 | 3.94 |
| 312.30 | 2.37 | 2.37 |
| 414.44 | 4.95 | 4.95 |
| 413.27 | 3.42 | 3.42 |
| 369.34 | 4.82 | 4.82 |
| 316.39 | 2.78 | 2.78 |
| 454.62 | 4.48 | 4.48 |
| 414.90 | 3.76 | 3.76 |
| 391.43 | 3.28 | 3.28 |
| 452.89 | 4.67 | 4.67 |
| 427.44 | 3.59 | 3.59 |
| 375.42 | 4.83 | 4.83 |
| 326.40 | 4.85 | 4.85 |
| 344.75 | 1.81 | 1.81 |
| 493.45 | 4.03 | 4.03 |
| 381.41 | 2.60 | 2.60 |
| 310.44 | 2.89 | 2.89 |
| 460.44 | 4.53 | 4.53 |
| 293.42 | 4.08 | 4.08 |
| 367.41 | 2.65 | 2.65 |
| 328.83 | 2.07 | 2.07 |
| 310.39 | 4.57 | 4.57 |
| 434.63 | 4.02 | 4.02 |
| 386.52 | 4.42 | 4.42 |
| 342.35 | 3.28 | 3.28 |
| 390.29 | 3.18 | 3.18 |
| 319.57 | 6.17 | 6.17 |
| 358.35 | 3.93 | 3.93 |
| 278.17 | 0.72 | 0.72 |
| 391.56 | 3.69 | 3.69 |
| 329.78 | 4.47 | 4.47 |
| 331.40 | 2.99 | 2.99 |
| 438.53 | 3.84 | 3.84 |
| 432.48 | 2.66 | 2.66 |
| 411.50 | 4.28 | 4.28 |
| 446.79 | 3.47 | 3.47 |
| 419.83 | 2.59 | 2.59 |
| 361.32 | 3.46 | 3.46 |
| 506.52 | 0.23 | 0.23 |
| 315.35 | 2.67 | 2.67 |
| 527.39 | 1.95 | 1.95 |
| 242.28 | 3.23 | 3.23 |
| 462.51 | 1.40 | 1.40 |
| 454.24 | 3.64 | 3.64 |
| 502.42 | 6.19 | 6.19 |
| 388.49 | 2.72 | 2.72 |
| 378.15 | 3.82 | 3.82 |
| 467.55 | 3.52 | 3.52 |
| 376.82 | 2.81 | 2.81 |
| 385.42 | 2.84 | 2.84 |
| 470.60 | 3.35 | 3.35 |
| 482.00 | 5.84 | 5.84 |
| 360.40 | 3.63 | 3.63 |
| 512.55 | 0.29 | 0.29 |
| 282.30 | 2.54 | 2.54 |
| 367.45 | 3.51 | 3.51 |
| 455.58 | 3.71 | 3.71 |
| 472.57 | 2.19 | 2.19 |
| 372.49 | 3.74 | 3.74 |
| 410.48 | 3.28 | 3.28 |
| 297.31 | 2.79 | 2.79 |
| 337.33 | 3.05 | 3.05 |
| 640.71 | 4.95 | 4.95 |
| 346.43 | 4.38 | 4.38 |
| 312.43 | 3.62 | 3.62 |
| 497.57 | 3.35 | 3.35 |
| 416.46 | 1.72 | 1.72 |
| 283.29 | 1.94 | 1.94 |
| 411.48 | 3.72 | 3.72 |
| 462.48 | 1.54 | 1.54 |
| 370.79 | 2.75 | 2.75 |
| 435.48 | 5.88 | 5.88 |
| 385.23 | 3.93 | 3.93 |
| 420.58 | 4.67 | 4.67 |
| 343.45 | 2.50 | 2.50 |
| 265.32 | 3.05 | 3.05 |
| 1199.41 | ||
| 470.50 | 3.53 | 3.53 |
| 491.57 | 1.68 | 1.68 |
| 429.48 | 3.33 | 3.33 |
| 318.40 | 2.91 | 2.91 |
| 332.43 | 3.21 | 3.21 |
| 459.62 | 4.50 | 4.50 |
| 359.39 | 3.51 | 3.51 |
| 343.38 | 3.18 | 3.18 |
| 345.20 | 4.22 | 4.22 |
| 351.41 | 2.88 | 2.88 |
| 404.42 | 4.20 | 4.20 |
| 333.37 | 1.81 | 1.81 |
| 340.77 | 3.14 | 3.14 |
| 359.38 | 2.89 | 2.89 |
| 429.52 | 3.24 | 3.24 |
| 472.62 | 4.76 | 4.76 |
| 428.99 | 4.66 | 4.66 |
| 435.48 | 5.88 | 5.88 |
| 446.46 | 2.37 | 2.37 |
| 404.49 | 1.95 | 1.95 |
| 351.20 | 3.63 | 3.63 |
| 417.45 | 2.69 | 2.69 |
| 383.86 | 4.37 | 4.37 |
| 375.84 | 3.74 | 3.74 |
| 490.39 | 5.16 | 5.16 |
| 358.20 | 3.40 | 3.40 |
| 324.26 | 3.73 | 3.73 |
| 350.81 | 5.15 | 5.15 |
| 335.19 | 4.72 | 4.72 |
| 531.43 | 5.03 | 5.03 |
| 401.42 | 3.76 | 3.76 |
| 314.34 | 4.23 | 4.23 |
| 511.56 | 2.51 | 2.51 |
| 289.34 | 3.50 | 3.50 |
| 358.40 | 3.20 | 3.20 |
| 373.66 | 4.70 | 4.70 |
| 293.28 | 2.60 | 2.60 |
| 414.44 | 4.50 | 4.50 |
| 299.36 | 2.28 | 2.28 |
| 411.49 | 5.59 | 5.59 |
| 419.28 | 4.56 | 4.56 |
| 497.51 | 3.23 | 3.23 |
| 249.25 | 1.17 | 1.17 |
| 454.87 | 4.72 | 4.72 |
| 382.42 | 4.93 | 4.93 |
| 352.35 | 2.62 | 2.62 |
| 424.45 | 2.19 | 2.19 |
| 365.43 | 3.37 | 3.37 |
| 329.43 | 2.75 | 2.75 |
| 381.30 | 3.96 | 3.96 |
| 313.74 | 3.29 | 3.29 |
| 347.42 | 2.81 | 2.81 |
| 398.49 | 5.21 | 5.21 |
| 308.34 | 3.65 | 3.65 |
| 365.35 | 1.96 | 1.96 |
| 353.42 | 3.07 | 3.07 |
| 325.19 | 3.65 | 3.65 |
| 352.37 | 3.18 | 3.18 |
| 321.38 | 3.02 | 3.02 |
| 380.40 | 3.23 | 3.23 |
| 413.38 | 3.17 | 3.17 |