Basic Information
ID: ALA2114820
Type: Functional
Description: PubChem BioAssay. Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5): Luminescence-based biochemical high throughput dose response assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1). (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114820
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 505.46 | 4.18 | 4.18 |
| 293.32 | 3.81 | 3.81 |
| 238.29 | 3.59 | 3.59 |
| 192.12 | -1.25 | -1.25 |
| 425.51 | 4.01 | 4.01 |
| 293.15 | 4.70 | 4.70 |
| 487.63 | 4.92 | 4.92 |
| 365.39 | 3.85 | 3.85 |
| 610.73 | 7.85 | 7.85 |
| 379.42 | 4.24 | 4.24 |
| 598.09 | 6.22 | 6.22 |
| 459.97 | 5.10 | 5.10 |
| 533.72 | 5.04 | 5.04 |
| 578.68 | 4.21 | 4.21 |
| 598.09 | 6.56 | 6.56 |
| 262.31 | 3.31 | 3.31 |
| 525.60 | 3.40 | 3.40 |
| 426.47 | 4.65 | 4.65 |
| 340.31 | 2.64 | 2.64 |
| 335.11 | 4.68 | 4.68 |
| 359.37 | 2.04 | 2.04 |
| 456.52 | 2.59 | 2.59 |
| 437.93 | 3.08 | 3.08 |
| 355.46 | 4.35 | 4.35 |
| 448.37 | 3.59 | 3.59 |
| 302.29 | 3.56 | 3.56 |
| 401.51 | 4.53 | 4.53 |
| 541.92 | 4.18 | 4.18 |
| 340.40 | 4.57 | 4.57 |
| 535.08 | 6.89 | 6.89 |
| 399.24 | 4.66 | 4.66 |
| 274.77 | 4.83 | 4.83 |
| 296.32 | 3.45 | 3.45 |
| 451.96 | 3.47 | 3.47 |
| 449.36 | 3.08 | 3.08 |
| 309.32 | 2.61 | 2.61 |
| 470.42 | 4.32 | 4.32 |
| 587.66 | 2.12 | 2.12 |
| 413.47 | 2.42 | 2.42 |
| 495.97 | 2.51 | 2.51 |
| 283.24 | 3.51 | 3.51 |
| 390.44 | 3.88 | 3.88 |
| 462.32 | 4.27 | 4.27 |
| 417.51 | 2.33 | 2.33 |
| 423.91 | 2.82 | 2.82 |
| 322.43 | 4.69 | 4.69 |
| 392.44 | 4.43 | 4.43 |
| 372.49 | 3.63 | 3.63 |
| 402.54 | 6.48 | 6.48 |
| 452.95 | 4.05 | 4.05 |
| 457.01 | 4.22 | 4.22 |
| 322.32 | 2.50 | 2.50 |
| 459.94 | 3.07 | 3.07 |
| 280.32 | 3.27 | 3.27 |
| 310.35 | 3.76 | 3.76 |
| 473.57 | 4.57 | 4.57 |
| 503.59 | 4.91 | 4.91 |
| 514.65 | 4.50 | 4.50 |
| 320.34 | 3.90 | 3.90 |
| 455.97 | 3.24 | 3.24 |
| 350.76 | 4.52 | 4.52 |
| 330.82 | 3.96 | 3.96 |
| 339.39 | 3.26 | 3.26 |
| 305.40 | 5.01 | 5.01 |
| 455.97 | 3.24 | 3.24 |
| 382.46 | 3.37 | 3.37 |
| 455.92 | 3.47 | 3.47 |
| 473.96 | 3.46 | 3.46 |
| 412.49 | 2.89 | 2.89 |
| 494.04 | 3.49 | 3.49 |
| 358.39 | 2.56 | 2.56 |
| 487.03 | 3.49 | 3.49 |
| 378.52 | 3.35 | 3.35 |
| 388.88 | 4.77 | 4.77 |
| 326.31 | 3.32 | 3.32 |
| 531.55 | 6.54 | 6.54 |
| 395.46 | 3.49 | 3.49 |
| 438.42 | 4.87 | 4.87 |
| 433.51 | 4.40 | 4.40 |
| 325.84 | 3.10 | 3.10 |
| 525.60 | 4.52 | 4.52 |
| 350.34 | 4.12 | 4.12 |
| 355.46 | 4.35 | 4.35 |
| 363.80 | 3.18 | 3.18 |
| 406.89 | 5.83 | 5.83 |
| 482.88 | 4.98 | 4.98 |
| 238.24 | 3.03 | 3.03 |
| 392.44 | 4.43 | 4.43 |
| 220.24 | 1.81 | 1.81 |
| 374.47 | 3.65 | 3.65 |
| 423.94 | 4.70 | 4.70 |
| 324.79 | 4.02 | 4.02 |
| 511.62 | 4.03 | 4.03 |
| 438.02 | 4.28 | 4.28 |
| 455.50 | 3.07 | 3.07 |
| 396.50 | 1.88 | 1.88 |
| 316.31 | 3.87 | 3.87 |
| 292.43 | 5.61 | 5.61 |
| 344.20 | 4.47 | 4.47 |
| 328.37 | 2.35 | 2.35 |
| 296.30 | 4.08 | 4.08 |
| 294.35 | 3.91 | 3.91 |
| 458.61 | 4.09 | 4.09 |
| 411.25 | 5.47 | 5.47 |
| 399.95 | 4.81 | 4.81 |
| 435.51 | 3.38 | 3.38 |
| 441.95 | 2.93 | 2.93 |
| 330.34 | 4.17 | 4.17 |
| 466.46 | 4.98 | 4.98 |
| 262.29 | 1.09 | 1.09 |
| 352.33 | 4.45 | 4.45 |
| 386.04 | 4.71 | 4.71 |
| 476.49 | 1.86 | 1.86 |
| 526.55 | 2.45 | 2.45 |
| 338.41 | 3.77 | 3.77 |
| 372.49 | 3.29 | 3.29 |
| 362.43 | 3.31 | 3.31 |
| 564.10 | 3.60 | 3.60 |
| 463.36 | 6.42 | 6.42 |
| 581.37 | 2.23 | 2.23 |
| 382.42 | 1.03 | 1.03 |
| 328.75 | 3.94 | 3.94 |
| 415.51 | 4.78 | 4.78 |
| 814.84 | 5.62 | 5.62 |
| 447.49 | 6.20 | 6.20 |
| 423.91 | 2.77 | 2.77 |
| 451.96 | 3.64 | 3.64 |
| 341.44 | 3.96 | 3.96 |
| 279.34 | 3.93 | 3.93 |
| 515.87 | 4.16 | 4.16 |
| 458.55 | 3.40 | 3.40 |
| 417.87 | 4.16 | 4.16 |
| 373.52 | 6.18 | 6.18 |
| 428.44 | 4.01 | 4.01 |
| 447.62 | 5.09 | 5.09 |
| 471.43 | 4.89 | 4.89 |
| 461.94 | 4.52 | 4.52 |
| 381.39 | 2.66 | 2.66 |
| 376.49 | 4.01 | 4.01 |
| 337.38 | 3.06 | 3.06 |
| 238.29 | 3.60 | 3.60 |
| 361.40 | 2.24 | 2.24 |
| 454.57 | 4.92 | 4.92 |
| 614.02 | 3.09 | 3.09 |
| 294.35 | 4.00 | 4.00 |
| 334.34 | 2.32 | 2.32 |
| 721.74 | 3.07 | 3.07 |
| 451.58 | 4.92 | 4.92 |
| 805.86 | 2.82 | 2.82 |
| 680.74 | 2.07 | 2.07 |
| 339.35 | 2.45 | 2.45 |
| 673.83 | 3.55 | 3.55 |
| 641.75 | 2.27 | 2.27 |
| 669.76 | 3.55 | 3.55 |
| 425.51 | 4.01 | 4.01 |
| 299.89 | 3.96 | 3.96 |
| 510.01 | 4.48 | 4.48 |
| 518.57 | 0.99 | 0.99 |
| 271.29 | 3.55 | 3.55 |
| 697.85 | 3.55 | 3.55 |
| 340.38 | 2.92 | 2.92 |
| 317.43 | 5.12 | 5.12 |
| 458.54 | 3.71 | 3.71 |
| 374.37 | 3.20 | 3.20 |
| 360.37 | 2.71 | 2.71 |
| 351.71 | 2.70 | 2.70 |
| 504.66 | 4.29 | 4.29 |
| 465.55 | 5.71 | 5.71 |
| 511.58 | 6.23 | 6.23 |
| 477.56 | 5.83 | 5.83 |
| 467.53 | 5.44 | 5.44 |
| 370.41 | 4.53 | 4.53 |
| 483.49 | 5.57 | 5.57 |
| 419.46 | 4.30 | 4.30 |
| 500.56 | 6.05 | 6.05 |
| 391.47 | 4.06 | 4.06 |
| 467.50 | 5.64 | 5.64 |
| 502.53 | 5.44 | 5.44 |
| 503.60 | 6.36 | 6.36 |
| 503.48 | 5.58 | 5.58 |
| 446.51 | 5.76 | 5.76 |
| 453.47 | 4.70 | 4.70 |
| 566.48 | 4.26 | 4.26 |
| 485.54 | 5.72 | 5.72 |
| 452.51 | 4.57 | 4.57 |
| 441.49 | 4.91 | 4.91 |
| 497.48 | 4.79 | 4.79 |
| 460.49 | 4.43 | 4.43 |
| 455.51 | 5.30 | 5.30 |
| 525.61 | 7.17 | 7.17 |
| 445.52 | 4.56 | 4.56 |
| 449.51 | 5.50 | 5.50 |
| 532.62 | 0.81 | 0.81 |
| 426.48 | 4.03 | 4.03 |
| 433.46 | 2.26 | 2.26 |
| 501.54 | 6.05 | 6.05 |
| 457.53 | 4.70 | 4.70 |
| 469.46 | 5.18 | 5.18 |
| 401.47 | 4.16 | 4.16 |
| 478.55 | 5.24 | 5.24 |
| 479.54 | 5.51 | 5.51 |
| 495.50 | 5.71 | 5.71 |
| 530.54 | 5.20 | 5.20 |
| 504.50 | 4.53 | 4.53 |
| 475.50 | 5.31 | 5.31 |
| 476.49 | 4.76 | 4.76 |
| 366.38 | 2.40 | 2.40 |
| 445.58 | 6.51 | 6.51 |
| 433.48 | 4.69 | 4.69 |
| 431.49 | 4.17 | 4.17 |
| 481.51 | 4.90 | 4.90 |
| 499.57 | 6.65 | 6.65 |
| 427.50 | 4.69 | 4.69 |
| 402.45 | 3.56 | 3.56 |
| 306.45 | 1.95 | 1.95 |
| 451.48 | 4.89 | 4.89 |
| 379.46 | 3.91 | 3.91 |
| 451.53 | 5.31 | 5.31 |
| 440.50 | 4.42 | 4.42 |
| 477.56 | 5.85 | 5.85 |
| 435.48 | 4.56 | 4.56 |
| 452.51 | 4.71 | 4.71 |
| 517.51 | 6.52 | 6.52 |
| 450.50 | 4.90 | 4.90 |
| 365.43 | 3.52 | 3.52 |
| 445.49 | 4.83 | 4.83 |
| 399.45 | 3.92 | 3.92 |
| 465.51 | 4.57 | 4.57 |
| 356.39 | 4.14 | 4.14 |
| 474.52 | 5.37 | 5.37 |
| 509.52 | 4.66 | 4.66 |
| 609.83 | 4.97 | 4.97 |
| 287.71 | 2.58 | 2.58 |