Basic Information
ID: ALA2114832
Type: Functional
Description: PubChem BioAssay. Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - HeLa Cytotoxicity. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA2114832
CC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.53 | 0.00 | 0.00 |
| 444.49 | -0.14 | -0.14 |
| 276.34 | 4.49 | 4.49 |
| 328.37 | 2.12 | 2.12 |
| 344.44 | 2.59 | 2.59 |
| 334.87 | 4.60 | 4.60 |
| 418.28 | 3.92 | 3.92 |
| 286.24 | 2.28 | 2.28 |
| 328.44 | 3.40 | 3.40 |
| 356.49 | 4.18 | 4.18 |
| 337.81 | 4.43 | 4.43 |
| 323.36 | 1.51 | 1.51 |
| 510.06 | 6.08 | 6.08 |
| 257.31 | 3.06 | 3.06 |
| 261.73 | 3.71 | 3.71 |
| 422.54 | 2.68 | 2.68 |
| 384.45 | 6.46 | 6.46 |
| 259.74 | 1.98 | 1.98 |
| 400.36 | 2.93 | 2.93 |
| 333.35 | 3.29 | 3.29 |
| 255.32 | 3.72 | 3.72 |
| 285.33 | 3.36 | 3.36 |
| 363.42 | 2.61 | 2.61 |
| 310.40 | 1.73 | 1.73 |
| 386.41 | 3.98 | 3.98 |
| 282.37 | 4.28 | 4.28 |
| 327.43 | 5.95 | 5.95 |
| 525.09 | 4.92 | 4.92 |
| 339.38 | 2.98 | 2.98 |
| 462.98 | 5.25 | 5.25 |
| 319.19 | 4.45 | 4.45 |
| 475.63 | 5.11 | 5.11 |
| 250.28 | 1.54 | 1.54 |
| 460.38 | 4.93 | 4.93 |
| 418.99 | 4.81 | 4.81 |
| 362.90 | 5.04 | 5.04 |
| 273.38 | 4.51 | 4.51 |
| 300.37 | 4.45 | 4.45 |
| 329.36 | 4.73 | 4.73 |
| 564.15 | 4.58 | 4.58 |
| 302.28 | 1.72 | 1.72 |
| 416.31 | 3.90 | 3.90 |
| 529.69 | 4.69 | 4.69 |
| 444.71 | 4.44 | 4.44 |
| 342.38 | 3.19 | 3.19 |
| 369.76 | 3.27 | 3.27 |
| 244.25 | 2.73 | 2.73 |
| 461.59 | 5.00 | 5.00 |
| 350.33 | -0.21 | -0.21 |
| 351.36 | 3.02 | 3.02 |
| 427.46 | 1.70 | 1.70 |
| 377.44 | 1.84 | 1.84 |
| 357.46 | 3.74 | 3.74 |
| 351.48 | 4.16 | 4.16 |
| 275.30 | 3.20 | 3.20 |
| 460.57 | 3.97 | 3.97 |
| 384.44 | 5.29 | 5.29 |
| 430.28 | 4.18 | 4.18 |
| 339.42 | 4.28 | 4.28 |
| 369.38 | 2.85 | 2.85 |
| 534.65 | 5.41 | 5.41 |
| 298.37 | 4.27 | 4.27 |
| 541.92 | 4.18 | 4.18 |
| 209.25 | 2.81 | 2.81 |
| 325.33 | 1.63 | 1.63 |
| 360.82 | 4.14 | 4.14 |
| 267.36 | 3.60 | 3.60 |
| 440.32 | 5.72 | 5.72 |
| 389.91 | 2.47 | 2.47 |
| 472.61 | 3.45 | 3.45 |
| 314.77 | 3.83 | 3.83 |
| 463.32 | 3.90 | 3.90 |
| 556.61 | 3.93 | 3.93 |
| 278.33 | 1.43 | 1.43 |
| 438.45 | 4.33 | 4.33 |
| 418.32 | 6.29 | 6.29 |
| 395.46 | 4.96 | 4.96 |
| 352.81 | 2.92 | 2.92 |
| 295.29 | 2.74 | 2.74 |
| 546.67 | 4.61 | 4.61 |
| 252.27 | 2.93 | 2.93 |
| 287.37 | 3.80 | 3.80 |
| 285.32 | 2.84 | 2.84 |
| 393.87 | 4.55 | 4.55 |
| 370.41 | 4.27 | 4.27 |
| 361.43 | 4.96 | 4.96 |
| 330.41 | 1.36 | 1.36 |
| 442.44 | 4.63 | 4.63 |
| 406.48 | 3.36 | 3.36 |
| 416.42 | 6.64 | 6.64 |
| 477.49 | 3.74 | 3.74 |
| 407.89 | 4.91 | 4.91 |
| 474.41 | 5.39 | 5.39 |
| 557.26 | 5.32 | 5.32 |
| 374.35 | 4.51 | 4.51 |
| 356.40 | 3.49 | 3.49 |
| 356.54 | 4.49 | 4.49 |
| 323.78 | 3.59 | 3.59 |
| 390.48 | 4.45 | 4.45 |
| 531.68 | 5.12 | 5.12 |
| 435.43 | 2.77 | 2.77 |
| 380.40 | 3.95 | 3.95 |
| 245.28 | 3.19 | 3.19 |
| 329.38 | 3.91 | 3.91 |
| 355.67 | 4.48 | 4.48 |
| 250.31 | 3.90 | 3.90 |
| 517.41 | -0.14 | -0.14 |
| 488.44 | 5.69 | 5.69 |
| 312.37 | 3.53 | 3.53 |
| 506.63 | 5.30 | 5.30 |
| 373.80 | 4.84 | 4.84 |
| 200.27 | 3.29 | 3.29 |
| 360.89 | 4.96 | 4.96 |
| 374.68 | 4.73 | 4.73 |
| 467.52 | 3.72 | 3.72 |
| 260.14 | 3.51 | 3.51 |
| 305.42 | 4.44 | 4.44 |
| 319.14 | 1.09 | 1.09 |
| 339.40 | 3.31 | 3.31 |
| 295.45 | 4.88 | 4.88 |
| 326.78 | 3.69 | 3.69 |
| 431.83 | 4.08 | 4.08 |
| 566.17 | 2.31 | 2.31 |
| 278.31 | 3.94 | 3.94 |
| 327.45 | 3.14 | 3.14 |
| 438.32 | 4.71 | 4.71 |
| 415.91 | 4.13 | 4.13 |
| 558.58 | 4.26 | 4.26 |
| 391.25 | 4.82 | 4.82 |
| 421.52 | 4.97 | 4.97 |
| 502.65 | 4.46 | 4.46 |
| 409.87 | 5.12 | 5.12 |
| 388.25 | 3.92 | 3.92 |
| 269.26 | 3.48 | 3.48 |
| 464.52 | 5.12 | 5.12 |
| 388.85 | 3.90 | 3.90 |
| 493.59 | 3.25 | 3.25 |
| 293.28 | 1.64 | 1.64 |
| 270.31 | 3.28 | 3.28 |
| 537.39 | 4.22 | 4.22 |
| 409.47 | 3.33 | 3.33 |
| 423.89 | 4.14 | 4.14 |
| 275.31 | 3.58 | 3.58 |
| 526.53 | 4.11 | 4.11 |
| 438.55 | 3.33 | 3.33 |
| 281.27 | 2.44 | 2.44 |
| 430.33 | 4.38 | 4.38 |
| 419.72 | 4.28 | 4.28 |
| 418.25 | 4.95 | 4.95 |
| 346.39 | 4.27 | 4.27 |
| 356.40 | 3.49 | 3.49 |
| 368.35 | 3.06 | 3.06 |
| 434.57 | 3.23 | 3.23 |
| 286.72 | 3.81 | 3.81 |
| 241.32 | 3.13 | 3.13 |
| 463.32 | 3.90 | 3.90 |
| 295.29 | 2.75 | 2.75 |
| 321.34 | 3.35 | 3.35 |
| 291.31 | 3.35 | 3.35 |
| 426.84 | 4.92 | 4.92 |
| 379.85 | 5.11 | 5.11 |
| 420.92 | 4.52 | 4.52 |
| 331.76 | 3.79 | 3.79 |
| 388.22 | 3.90 | 3.90 |
| 245.28 | 3.19 | 3.19 |
| 368.43 | 4.06 | 4.06 |
| 372.28 | 2.86 | 2.86 |
| 375.49 | 4.76 | 4.76 |
| 299.36 | 3.67 | 3.67 |
| 476.83 | 3.99 | 3.99 |
| 391.47 | 2.15 | 2.15 |
| 281.36 | 2.97 | 2.97 |
| 314.41 | 3.80 | 3.80 |
| 281.32 | 3.03 | 3.03 |
| 344.51 | 4.78 | 4.78 |
| 376.32 | 2.17 | 2.17 |
| 451.82 | 5.01 | 5.01 |
| 282.30 | 1.89 | 1.89 |
| 335.41 | 4.15 | 4.15 |
| 400.43 | 4.28 | 4.28 |
| 441.58 | 5.45 | 5.45 |
| 384.48 | 5.09 | 5.09 |
| 423.90 | 3.79 | 3.79 |
| 412.92 | 4.35 | 4.35 |
| 296.78 | 2.75 | 2.75 |
| 405.50 | 3.01 | 3.01 |
| 292.34 | 3.29 | 3.29 |
| 295.30 | 2.03 | 2.03 |
| 504.38 | 4.26 | 4.26 |
| 310.38 | 3.91 | 3.91 |
| 451.45 | 5.00 | 5.00 |
| 281.27 | 3.25 | 3.25 |
| 420.52 | 2.24 | 2.24 |
| 375.45 | 5.26 | 5.26 |
| 328.38 | 3.73 | 3.73 |
| 468.34 | 2.41 | 2.41 |
| 374.35 | 3.03 | 3.03 |
| 385.27 | 3.62 | 3.62 |
| 474.41 | 5.39 | 5.39 |
| 380.50 | 2.70 | 2.70 |
| 267.28 | 3.24 | 3.24 |
| 403.44 | 4.54 | 4.54 |
| 443.37 | 3.52 | 3.52 |
| 390.49 | 3.64 | 3.64 |
| 346.39 | 3.96 | 3.96 |
| 377.54 | 4.74 | 4.74 |
| 425.87 | 3.70 | 3.70 |
| 291.31 | 3.34 | 3.34 |
| 418.47 | 3.99 | 3.99 |
| 814.84 | 5.62 | 5.62 |
| 282.30 | 3.59 | 3.59 |
| 331.42 | 4.11 | 4.11 |
| 368.93 | 6.05 | 6.05 |
| 548.68 | 5.01 | 5.01 |
| 518.50 | 5.74 | 5.74 |
| 273.33 | 3.81 | 3.81 |
| 375.45 | 5.26 | 5.26 |
| 325.39 | 3.93 | 3.93 |
| 382.46 | 4.50 | 4.50 |
| 358.44 | 3.63 | 3.63 |
| 254.29 | 3.70 | 3.70 |
| 317.39 | 4.63 | 4.63 |
| 341.80 | 4.39 | 4.39 |
| 430.33 | 4.38 | 4.38 |
| 261.73 | 3.71 | 3.71 |
| 492.15 | 6.80 | 6.80 |
| 574.58 | 4.16 | 4.16 |
| 279.72 | 3.84 | 3.84 |
| 498.36 | 4.80 | 4.80 |
| 296.18 | 4.36 | 4.36 |
| 477.74 | 0.71 | 0.71 |
| 471.51 | 4.90 | 4.90 |
| 199.26 | 0.51 | 0.51 |
| 562.01 | 4.85 | 4.85 |
| 245.28 | 3.19 | 3.19 |
| 414.40 | 2.97 | 2.97 |
| 332.40 | 3.65 | 3.65 |
| 389.24 | 0.54 | 0.54 |
| 282.09 | 2.02 | 2.02 |
| 465.50 | 2.84 | 2.84 |
| 307.63 | 3.85 | 3.85 |
| 440.54 | 1.23 | 1.23 |
| 430.52 | 5.61 | 5.61 |
| 358.83 | 2.12 | 2.12 |
| 543.57 | 3.90 | 3.90 |
| 260.34 | 4.79 | 4.79 |
| 372.90 | 3.03 | 3.03 |
| 423.52 | 4.88 | 4.88 |
| 517.46 | 3.94 | 3.94 |
| 412.49 | 0.45 | 0.45 |
| 535.55 | 1.45 | 1.45 |
| 484.50 | 4.13 | 4.13 |
| 273.33 | 3.81 | 3.81 |
| 414.09 | 7.88 | 7.88 |
| 238.29 | 2.96 | 2.96 |
| 279.24 | 1.84 | 1.84 |
| 590.76 | 5.90 | 5.90 |
| 306.20 | 3.19 | 3.19 |
| 541.74 | 6.74 | 6.74 |
| 410.95 | 3.52 | 3.52 |
| 308.34 | 4.30 | 4.30 |
| 505.56 | 3.41 | 3.41 |
| 521.58 | 5.59 | 5.59 |
| 296.20 | 1.98 | 1.98 |
| 714.56 | 3.55 | 3.55 |
| 380.49 | 2.02 | 2.02 |
| 304.36 | 2.38 | 2.38 |
| 502.58 | 6.69 | 6.69 |
| 458.04 | 5.09 | 5.09 |
| 523.53 | 2.71 | 2.71 |
| 678.15 | 6.44 | 6.44 |
| 324.34 | 2.57 | 2.57 |
| 248.29 | 2.99 | 2.99 |
| 484.50 | 6.78 | 6.78 |
| 412.97 | 4.97 | 4.97 |
| 338.32 | 2.43 | 2.43 |
| 400.91 | 3.29 | 3.29 |
| 593.22 | 7.93 | 7.93 |
| 546.16 | 7.01 | 7.01 |
| 416.31 | 3.90 | 3.90 |
| 448.13 | 4.75 | 4.75 |
| 415.47 | 3.99 | 3.99 |
| 360.35 | 3.62 | 3.62 |
| 305.83 | 3.69 | 3.69 |
| 357.79 | 4.35 | 4.35 |
| 482.65 | 5.95 | 5.95 |
| 311.41 | 3.01 | 3.01 |
| 469.42 | 3.66 | 3.66 |
| 278.31 | 3.89 | 3.89 |
| 400.44 | 1.01 | 1.01 |
| 458.54 | 3.71 | 3.71 |
| 297.24 | 2.96 | 2.96 |
| 337.38 | 3.71 | 3.71 |
| 288.35 | 4.04 | 4.04 |
| 305.38 | 4.31 | 4.31 |
| 265.27 | 3.26 | 3.26 |
| 262.23 | 0.55 | 0.55 |
| 351.41 | 4.02 | 4.02 |
| 464.43 | 1.80 | 1.80 |
| 248.67 | 2.28 | 2.28 |
| 188.19 | 2.42 | 2.42 |
| 382.38 | 2.03 | 2.03 |
| 299.37 | 3.20 | 3.20 |
| 230.23 | 2.37 | 2.37 |
| 335.41 | 3.42 | 3.42 |
| 317.39 | 2.99 | 2.99 |
| 343.41 | 3.41 | 3.41 |
| 354.44 | 3.73 | 3.73 |
| 430.47 | 3.36 | 3.36 |
| 392.42 | 3.97 | 3.97 |
| 379.24 | 2.74 | 2.74 |
| 410.48 | 3.82 | 3.82 |
| 540.23 | 5.32 | 5.32 |
| 275.31 | 3.49 | 3.49 |
| 241.29 | 3.41 | 3.41 |
| 296.33 | 3.03 | 3.03 |
| 231.09 | 1.81 | 1.81 |
| 281.27 | 2.74 | 2.74 |
| 282.30 | 2.72 | 2.72 |
| 400.44 | 1.01 | 1.01 |
| 308.34 | 3.38 | 3.38 |
| 381.41 | 3.36 | 3.36 |
| 387.44 | 4.05 | 4.05 |
| 331.42 | 3.96 | 3.96 |
| 343.43 | 3.00 | 3.00 |
| 305.38 | 4.31 | 4.31 |
| 434.47 | 3.77 | 3.77 |
| 334.34 | 2.44 | 2.44 |
| 299.33 | 2.95 | 2.95 |
| 511.56 | 2.51 | 2.51 |
| 454.96 | 2.39 | 2.39 |
| 289.34 | 3.50 | 3.50 |
| 375.45 | 4.75 | 4.75 |
| 313.74 | 3.75 | 3.75 |
| 359.39 | 3.41 | 3.41 |
| 321.83 | 3.68 | 3.68 |
| 304.31 | 2.43 | 2.43 |
| 304.35 | 3.60 | 3.60 |
| 378.41 | 3.73 | 3.73 |
| 374.47 | 2.80 | 2.80 |
| 339.21 | 4.02 | 4.02 |
| 265.36 | 2.50 | 2.50 |
| 319.45 | 4.77 | 4.77 |
| 319.43 | 2.39 | 2.39 |
| 290.75 | 3.52 | 3.52 |
| 320.35 | 3.31 | 3.31 |
| 319.45 | 4.77 | 4.77 |
| 327.20 | 2.69 | 2.69 |
| 408.51 | 1.97 | 1.97 |
| 403.44 | 3.73 | 3.73 |
| 357.45 | 3.39 | 3.39 |
| 397.54 | 5.05 | 5.05 |
| 276.25 | -0.33 | -0.33 |
| 526.54 | 1.21 | 1.21 |
| 975.12 | 4.70 | 4.70 |