Basic Information
ID: ALA2114844
Type: Functional
Description: PubChem BioAssay. Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3):Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16). (Class of assay: confirmatory)
Organism: Human alphaherpesvirus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2114844
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.37 | 1.66 | 1.66 |
| 210.19 | 1.21 | 1.21 |
| 294.31 | -0.89 | -0.89 |
| 418.57 | 4.59 | 4.59 |
| 363.37 | 1.66 | 1.66 |
| 214.66 | 3.44 | 3.44 |
| 422.54 | 2.68 | 2.68 |
| 262.30 | 1.25 | 1.25 |
| 393.48 | 4.84 | 4.84 |
| 380.35 | 3.63 | 3.63 |
| 210.19 | 1.52 | 1.52 |
| 433.46 | 4.63 | 4.63 |
| 241.25 | 1.91 | 1.91 |
| 268.35 | 3.65 | 3.65 |
| 386.43 | 3.32 | 3.32 |
| 342.81 | 4.26 | 4.26 |
| 416.31 | 3.90 | 3.90 |
| 346.22 | 3.60 | 3.60 |
| 383.43 | 2.74 | 2.74 |
| 343.41 | 5.37 | 5.37 |
| 474.97 | 3.71 | 3.71 |
| 498.63 | 3.10 | 3.10 |
| 361.46 | 3.69 | 3.69 |
| 402.52 | 5.66 | 5.66 |
| 317.42 | 1.61 | 1.61 |
| 309.37 | 3.67 | 3.67 |
| 317.44 | 3.45 | 3.45 |
| 319.36 | 3.67 | 3.67 |
| 432.27 | 4.86 | 4.86 |
| 498.27 | 5.64 | 5.64 |
| 456.53 | 3.94 | 3.94 |
| 401.29 | 4.47 | 4.47 |
| 415.44 | 4.38 | 4.38 |
| 289.40 | 3.35 | 3.35 |
| 503.66 | 6.49 | 6.49 |
| 317.44 | 3.45 | 3.45 |
| 388.90 | 3.02 | 3.02 |
| 311.20 | 3.40 | 3.40 |
| 298.41 | 4.64 | 4.64 |
| 362.46 | 4.11 | 4.11 |
| 375.38 | 3.30 | 3.30 |
| 302.36 | 3.39 | 3.39 |
| 357.31 | 1.65 | 1.65 |
| 330.41 | 4.73 | 4.73 |
| 343.36 | 3.14 | 3.14 |
| 369.49 | 4.14 | 4.14 |
| 328.80 | 4.06 | 4.06 |
| 312.32 | 4.01 | 4.01 |
| 488.61 | 3.24 | 3.24 |
| 462.35 | 5.53 | 5.53 |
| 392.01 | 1.56 | 1.56 |
| 329.36 | 3.16 | 3.16 |
| 329.43 | 2.75 | 2.75 |
| 292.19 | 2.96 | 2.96 |
| 401.27 | 3.29 | 3.29 |
| 357.39 | 3.53 | 3.53 |
| 422.39 | 3.85 | 3.85 |
| 420.81 | 2.28 | 2.28 |
| 414.53 | 2.28 | 2.28 |
| 278.36 | 3.90 | 3.90 |
| 463.94 | 6.17 | 6.17 |
| 378.26 | 3.67 | 3.67 |
| 347.81 | 1.57 | 1.57 |
| 261.71 | 2.83 | 2.83 |
| 353.45 | 3.46 | 3.46 |
| 324.81 | 5.00 | 5.00 |
| 355.78 | 4.21 | 4.21 |
| 338.86 | 4.27 | 4.27 |
| 339.42 | 2.97 | 2.97 |
| 371.48 | 5.55 | 5.55 |
| 414.87 | 2.37 | 2.37 |
| 347.83 | 4.63 | 4.63 |
| 364.41 | 3.17 | 3.17 |
| 491.41 | 2.65 | 2.65 |
| 476.00 | 3.68 | 3.68 |
| 383.40 | 3.51 | 3.51 |
| 417.49 | 4.76 | 4.76 |
| 379.87 | 2.79 | 2.79 |
| 481.62 | 4.64 | 4.64 |
| 374.68 | 4.73 | 4.73 |
| 454.02 | 4.86 | 4.86 |
| 372.51 | 4.41 | 4.41 |
| 513.40 | 5.78 | 5.78 |
| 302.38 | 4.24 | 4.24 |
| 376.39 | 3.09 | 3.09 |
| 190.16 | 1.85 | 1.85 |
| 354.45 | 2.37 | 2.37 |
| 283.33 | 2.07 | 2.07 |
| 406.53 | 2.66 | 2.66 |
| 267.29 | 2.82 | 2.82 |
| 380.49 | 3.92 | 3.92 |
| 415.43 | 2.14 | 2.14 |
| 291.38 | 2.79 | 2.79 |
| 241.32 | 3.30 | 3.30 |
| 429.48 | 3.63 | 3.63 |
| 409.50 | 3.22 | 3.22 |
| 322.39 | 3.91 | 3.91 |
| 380.44 | 3.93 | 3.93 |
| 323.83 | 3.40 | 3.40 |
| 278.36 | 3.90 | 3.90 |
| 393.27 | 3.41 | 3.41 |
| 364.43 | 4.50 | 4.50 |
| 476.04 | 4.26 | 4.26 |
| 463.56 | 6.15 | 6.15 |
| 472.95 | 4.49 | 4.49 |
| 442.97 | 4.29 | 4.29 |
| 430.33 | 4.32 | 4.32 |
| 429.92 | 3.57 | 3.57 |
| 405.55 | 3.90 | 3.90 |
| 426.92 | 3.89 | 3.89 |
| 424.52 | 2.77 | 2.77 |
| 214.18 | 0.89 | 0.89 |
| 454.81 | 5.90 | 5.90 |
| 496.66 | 4.09 | 4.09 |
| 317.44 | 4.02 | 4.02 |
| 415.56 | 3.66 | 3.66 |
| 299.40 | 3.45 | 3.45 |
| 335.41 | 3.09 | 3.09 |
| 358.42 | 2.32 | 2.32 |
| 330.42 | 4.29 | 4.29 |
| 389.31 | 4.14 | 4.14 |
| 441.87 | 1.59 | 1.59 |
| 395.41 | 3.55 | 3.55 |
| 330.43 | 3.73 | 3.73 |
| 360.44 | 4.85 | 4.85 |
| 412.47 | 3.03 | 3.03 |
| 307.38 | 4.51 | 4.51 |
| 292.34 | 3.32 | 3.32 |
| 438.56 | 5.08 | 5.08 |
| 377.44 | 3.64 | 3.64 |
| 331.44 | 3.15 | 3.15 |
| 434.50 | 2.85 | 2.85 |
| 432.53 | 3.40 | 3.40 |
| 329.81 | 4.35 | 4.35 |
| 430.52 | 2.50 | 2.50 |
| 323.83 | 3.40 | 3.40 |
| 343.81 | 3.01 | 3.01 |
| 351.36 | 3.66 | 3.66 |
| 219.20 | 0.11 | 0.11 |
| 381.50 | 4.46 | 4.46 |
| 290.35 | 2.57 | 2.57 |
| 545.04 | 3.70 | 3.70 |
| 398.45 | 5.27 | 5.27 |
| 388.52 | 3.81 | 3.81 |
| 319.25 | 1.80 | 1.80 |
| 446.92 | 2.59 | 2.59 |
| 303.70 | 2.61 | 2.61 |
| 385.27 | 3.62 | 3.62 |
| 405.38 | 3.50 | 3.50 |
| 347.37 | 2.62 | 2.62 |
| 335.82 | 3.10 | 3.10 |
| 455.89 | 1.73 | 1.73 |
| 329.77 | 3.09 | 3.09 |
| 369.24 | 3.34 | 3.34 |
| 391.47 | 4.29 | 4.29 |
| 496.64 | 2.68 | 2.68 |
| 408.89 | 5.12 | 5.12 |
| 510.06 | 6.66 | 6.66 |
| 327.39 | 4.51 | 4.51 |
| 368.46 | 4.64 | 4.64 |
| 396.53 | 3.34 | 3.34 |
| 373.87 | 4.89 | 4.89 |
| 327.82 | 3.85 | 3.85 |
| 267.26 | 2.33 | 2.33 |
| 428.44 | 5.55 | 5.55 |
| 494.44 | 6.01 | 6.01 |
| 312.73 | 3.05 | 3.05 |
| 334.42 | 2.96 | 2.96 |
| 293.41 | 4.34 | 4.34 |
| 414.40 | 2.97 | 2.97 |
| 376.46 | 3.49 | 3.49 |
| 430.52 | 5.61 | 5.61 |
| 471.43 | 4.89 | 4.89 |
| 359.41 | 2.21 | 2.21 |
| 339.39 | 5.18 | 5.18 |
| 431.51 | 2.71 | 2.71 |
| 305.42 | 4.44 | 4.44 |
| 581.32 | 6.95 | 6.95 |
| 274.13 | 3.32 | 3.32 |
| 555.58 | 1.63 | 1.63 |
| 338.41 | 0.50 | 0.50 |
| 465.43 | 3.04 | 3.04 |
| 293.41 | 4.55 | 4.55 |
| 549.99 | ||
| 411.34 | 5.48 | 5.48 |
| 482.43 | 6.01 | 6.01 |
| 262.30 | 1.25 | 1.25 |
| 362.49 | 5.08 | 5.08 |
| 342.81 | 3.33 | 3.33 |
| 484.94 | 1.77 | 1.77 |
| 416.31 | 3.90 | 3.90 |
| 278.29 | 3.30 | 3.30 |
| 392.45 | 3.66 | 3.66 |
| 253.06 | 1.03 | 1.03 |
| 424.41 | 1.79 | 1.79 |
| 496.51 | 3.06 | 3.06 |
| 509.02 | 3.59 | 3.59 |
| 411.00 | 3.50 | 3.50 |
| 444.37 | 4.32 | 4.32 |
| 507.60 | 3.89 | 3.89 |
| 356.45 | 5.03 | 5.03 |
| 452.45 | 4.55 | 4.55 |
| 483.50 | 3.66 | 3.66 |
| 489.58 | 5.24 | 5.24 |
| 492.58 | 4.63 | 4.63 |
| 323.45 | 4.84 | 4.84 |
| 413.56 | 5.27 | 5.27 |
| 397.43 | 2.70 | 2.70 |
| 257.32 | 1.80 | 1.80 |
| 454.48 | 5.61 | 5.61 |
| 320.35 | 2.95 | 2.95 |
| 282.13 | 3.26 | 3.26 |
| 280.36 | 1.96 | 1.96 |
| 317.39 | 2.99 | 2.99 |
| 450.45 | 3.89 | 3.89 |
| 382.47 | 1.90 | 1.90 |
| 522.56 | 5.55 | 5.55 |
| 665.23 | 6.18 | 6.18 |
| 423.42 | 5.33 | 5.33 |
| 342.36 | 1.26 | 1.26 |
| 378.22 | 3.64 | 3.64 |
| 436.89 | 4.33 | 4.33 |
| 433.55 | 4.89 | 4.89 |
| 433.45 | 4.63 | 4.63 |
| 371.20 | 3.52 | 3.52 |