ID: ALA2114851
Type: Functional
Description: PubChem BioAssay. Dose Response confirmation of uHTS small molecule hits for cystic fibrosis induced NFkb Inhibitors in a TNFa-induced IL8 counterscreen. (Class of assay: confirmatory)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2114851
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
322.42 | 3.50 | 3.50 |
264.32 | 1.61 | 1.61 |
361.47 | 5.29 | 5.29 |
380.47 | 4.69 | 4.69 |
287.32 | 2.91 | 2.91 |
424.53 | 2.50 | 2.50 |
318.31 | 1.38 | 1.38 |
306.32 | 2.13 | 2.13 |
302.40 | 3.31 | 3.31 |
257.25 | 1.66 | 1.66 |
705.66 | 5.71 | 5.71 |
227.27 | 1.91 | 1.91 |
563.62 | 6.14 | 6.14 |
296.33 | 3.47 | 3.47 |
251.29 | 1.74 | 1.74 |
269.31 | 2.47 | 2.47 |
330.32 | 1.55 | 1.55 |
416.53 | 5.43 | 5.43 |
255.28 | 2.93 | 2.93 |
336.34 | 2.14 | 2.14 |
302.34 | 3.90 | 3.90 |
427.37 | 2.40 | 2.40 |
646.59 | 3.96 | 3.96 |
315.17 | 3.40 | 3.40 |
256.31 | 2.29 | 2.29 |
483.34 | 4.20 | 4.20 |
457.57 | 5.00 | 5.00 |
463.38 | 5.29 | 5.29 |
345.36 | 4.23 | 4.23 |
373.84 | 1.50 | 1.50 |
277.39 | 3.08 | 3.08 |
322.16 | 2.37 | 2.37 |
382.84 | 5.60 | 5.60 |
350.27 | 4.93 | 4.93 |
429.86 | 2.59 | 2.59 |
341.50 | 0.14 | 0.14 |
336.23 | 3.03 | 3.03 |
356.21 | 3.35 | 3.35 |
255.25 | 2.95 | 2.95 |
480.03 | 5.34 | 5.34 |
331.48 | 1.86 | 1.86 |
282.30 | 3.16 | 3.16 |
428.47 | 4.13 | 4.13 |
429.82 | 3.01 | 3.01 |
280.33 | 3.76 | 3.76 |
341.36 | 2.14 | 2.14 |
466.00 | 4.13 | 4.13 |
248.71 | 3.03 | 3.03 |
368.41 | 4.11 | 4.11 |
337.30 | 3.91 | 3.91 |
205.26 | 1.54 | 1.54 |
352.86 | 2.07 | 2.07 |
252.27 | 2.52 | 2.52 |
424.41 | 1.79 | 1.79 |
348.44 | 2.16 | 2.16 |
459.64 | 4.02 | 4.02 |
295.35 | 2.14 | 2.14 |
193.21 | 2.37 | 2.37 |
388.50 | 3.99 | 3.99 |
393.37 | 3.82 | 3.82 |
286.19 | 3.66 | 3.66 |
390.48 | 2.73 | 2.73 |
341.83 | 3.74 | 3.74 |
348.83 | 4.85 | 4.85 |
246.27 | 2.94 | 2.94 |
340.43 | 4.84 | 4.84 |
246.27 | 2.94 | 2.94 |
381.44 | 4.67 | 4.67 |
318.57 | 4.63 | 4.63 |
521.46 | 5.04 | 5.04 |