ID: ALA2114863
Type: Functional
Description: PubChem BioAssay. Acumen qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in WT MEF Cells: Hit Validation. (Class of assay: confirmatory)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2114863
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
475.36 | 4.43 | 4.43 |
485.95 | 4.39 | 4.39 |
478.66 | 5.04 | 5.04 |
585.70 | 2.54 | 2.54 |
356.18 | 5.18 | 5.18 |
488.02 | 3.31 | 3.31 |
466.54 | 4.35 | 4.35 |
408.55 | 3.16 | 3.16 |
426.56 | 4.97 | 4.97 |
325.39 | 3.71 | 3.71 |
395.52 | 5.78 | 5.78 |
588.48 | 6.89 | 6.89 |
406.76 | 5.17 | 5.17 |
375.86 | 5.50 | 5.50 |
421.54 | 4.20 | 4.20 |
439.47 | 3.47 | 3.47 |
371.46 | 2.64 | 2.64 |
323.37 | 4.72 | 4.72 |
463.41 | 4.15 | 4.15 |
396.54 | 3.01 | 3.01 |
408.55 | 3.16 | 3.16 |
367.49 | 3.86 | 3.86 |
637.04 | 5.55 | 5.55 |
456.44 | 2.88 | 2.88 |
310.78 | 2.22 | 2.22 |
325.36 | 3.68 | 3.68 |
420.26 | 3.71 | 3.71 |
338.84 | 5.44 | 5.44 |
371.44 | 4.86 | 4.86 |
381.46 | 3.30 | 3.30 |
391.50 | 4.02 | 4.02 |
419.44 | 4.74 | 4.74 |
386.52 | 6.00 | 6.00 |
481.57 | 5.21 | 5.21 |
498.65 | 5.89 | 5.89 |
425.46 | 4.97 | 4.97 |
457.46 | 3.73 | 3.73 |
415.54 | 3.49 | 3.49 |
407.99 | 3.40 | 3.40 |
372.42 | 4.72 | 4.72 |
416.39 | 4.33 | 4.33 |
416.64 | 4.31 | 4.31 |
437.93 | 3.08 | 3.08 |
389.50 | 4.44 | 4.44 |
404.55 | 4.94 | 4.94 |
479.53 | 4.68 | 4.68 |
454.50 | 2.83 | 2.83 |
469.95 | 5.74 | 5.74 |
447.60 | 4.88 | 4.88 |
447.59 | 3.11 | 3.11 |
450.56 | 5.15 | 5.15 |
410.32 | 5.17 | 5.17 |
481.93 | 4.37 | 4.37 |
384.93 | 6.01 | 6.01 |
477.36 | 5.06 | 5.06 |
440.63 | 6.51 | 6.51 |
636.24 | 6.33 | 6.33 |
406.36 | 5.34 | 5.34 |
477.30 | 4.34 | 4.34 |
389.45 | 4.47 | 4.47 |
407.47 | 4.83 | 4.83 |
423.58 | 4.93 | 4.93 |
492.07 | 4.88 | 4.88 |
377.49 | 5.31 | 5.31 |
436.58 | 5.26 | 5.26 |
507.43 | 4.87 | 4.87 |
480.96 | 2.61 | 2.61 |
494.53 | 4.36 | 4.36 |
400.46 | 1.89 | 1.89 |
441.98 | 5.79 | 5.79 |
415.90 | 3.34 | 3.34 |
490.95 | 2.81 | 2.81 |
416.32 | 4.23 | 4.23 |
372.53 | 4.73 | 4.73 |
437.93 | 3.33 | 3.33 |
432.57 | 3.65 | 3.65 |
332.30 | 2.57 | 2.57 |
560.68 | 5.43 | 5.43 |
380.45 | 4.06 | 4.06 |
369.23 | 3.13 | 3.13 |
357.41 | 4.88 | 4.88 |
430.34 | 4.62 | 4.62 |
411.93 | 4.45 | 4.45 |
353.42 | 3.91 | 3.91 |
390.30 | 4.66 | 4.66 |
405.88 | 4.66 | 4.66 |
471.61 | 3.49 | 3.49 |
405.49 | 4.74 | 4.74 |
383.88 | 5.64 | 5.64 |
455.38 | 5.62 | 5.62 |
449.48 | 5.89 | 5.89 |
446.59 | 5.17 | 5.17 |
570.57 | 5.50 | 5.50 |
286.71 | 4.13 | 4.13 |
459.51 | 5.21 | 5.21 |
486.96 | 3.83 | 3.83 |
430.50 | 3.90 | 3.90 |
376.51 | 3.58 | 3.58 |
510.42 | 4.66 | 4.66 |
374.48 | 5.35 | 5.35 |
440.34 | 4.26 | 4.26 |
348.45 | 4.13 | 4.13 |
492.62 | 5.15 | 5.15 |
443.57 | 6.34 | 6.34 |
462.94 | 5.22 | 5.22 |
492.94 | 4.11 | 4.11 |
325.78 | 2.09 | 2.09 |
433.89 | 4.11 | 4.11 |
439.99 | 5.23 | 5.23 |
411.53 | 4.23 | 4.23 |
419.48 | 5.00 | 5.00 |
423.90 | 4.97 | 4.97 |
529.04 | 5.96 | 5.96 |
411.53 | 3.81 | 3.81 |
429.91 | 5.22 | 5.22 |
403.87 | 4.94 | 4.94 |
571.77 | 5.78 | 5.78 |
427.96 | 4.65 | 4.65 |
338.21 | 4.70 | 4.70 |
454.96 | 2.66 | 2.66 |
400.95 | 4.29 | 4.29 |
467.57 | 6.52 | 6.52 |
437.51 | 4.20 | 4.20 |
421.54 | 4.20 | 4.20 |
456.99 | 6.35 | 6.35 |
494.55 | 4.05 | 4.05 |
421.49 | 5.03 | 5.03 |
487.63 | 4.59 | 4.59 |
377.44 | 5.30 | 5.30 |
505.66 | 3.59 | 3.59 |
357.43 | 4.12 | 4.12 |
315.33 | 1.36 | 1.36 |
440.33 | 6.56 | 6.56 |
432.39 | 4.80 | 4.80 |
470.96 | 3.56 | 3.56 |
409.49 | 4.88 | 4.88 |
378.54 | 6.05 | 6.05 |
387.44 | 3.70 | 3.70 |
459.93 | 4.21 | 4.21 |
431.51 | 4.76 | 4.76 |
463.99 | 6.06 | 6.06 |
392.52 | 5.24 | 5.24 |
338.21 | 4.40 | 4.40 |
463.58 | 4.45 | 4.45 |
464.50 | 4.38 | 4.38 |
385.46 | 4.31 | 4.31 |
392.57 | 5.64 | 5.64 |
455.54 | 4.23 | 4.23 |
426.87 | 4.30 | 4.30 |
501.51 | 4.04 | 4.04 |
416.48 | 3.84 | 3.84 |
347.81 | 5.40 | 5.40 |
384.39 | 3.63 | 3.63 |
345.44 | 5.49 | 5.49 |
468.00 | 2.66 | 2.66 |
431.47 | 3.67 | 3.67 |
309.37 | 3.51 | 3.51 |
424.50 | 4.48 | 4.48 |
390.46 | 2.17 | 2.17 |
455.54 | 3.07 | 3.07 |
402.45 | 5.33 | 5.33 |
415.49 | 5.25 | 5.25 |
402.41 | 4.46 | 4.46 |
431.90 | 3.39 | 3.39 |
498.35 | 6.19 | 6.19 |
339.80 | 1.85 | 1.85 |
403.94 | 3.71 | 3.71 |
238.27 | 0.37 | 0.37 |
431.90 | 3.04 | 3.04 |
374.47 | 4.88 | 4.88 |
462.89 | 3.45 | 3.45 |
347.32 | 5.17 | 5.17 |
485.54 | 4.60 | 4.60 |
401.88 | 3.03 | 3.03 |
403.87 | 4.66 | 4.66 |
420.54 | 5.37 | 5.37 |
412.53 | 4.04 | 4.04 |
317.39 | 5.26 | 5.26 |
427.48 | 5.97 | 5.97 |
578.58 | 3.46 | 3.46 |
371.82 | 4.53 | 4.53 |
419.87 | 3.17 | 3.17 |
325.36 | 3.33 | 3.33 |
477.61 | 2.95 | 2.95 |
400.53 | 3.06 | 3.06 |
282.30 | 3.48 | 3.48 |
429.52 | 5.26 | 5.26 |
384.46 | 4.42 | 4.42 |
379.50 | 4.59 | 4.59 |
465.60 | 4.95 | 4.95 |
532.62 | 4.65 | 4.65 |
395.43 | 3.11 | 3.11 |
501.65 | 4.76 | 4.76 |
437.59 | 4.56 | 4.56 |
384.93 | 6.01 | 6.01 |
392.50 | 5.20 | 5.20 |
579.72 | 4.35 | 4.35 |
494.98 | 3.00 | 3.00 |
517.41 | -0.14 | -0.14 |
408.55 | 3.16 | 3.16 |
388.42 | 4.83 | 4.83 |
407.50 | 4.30 | 4.30 |
462.55 | 5.51 | 5.51 |
460.44 | 5.43 | 5.43 |
455.51 | 4.59 | 4.59 |
494.98 | 3.00 | 3.00 |
324.38 | 3.59 | 3.59 |
420.53 | 4.81 | 4.81 |
469.51 | 5.96 | 5.96 |
339.44 | 3.81 | 3.81 |
423.83 | 3.63 | 3.63 |
385.42 | 5.56 | 5.56 |
526.61 | 5.75 | 5.75 |
328.44 | 3.45 | 3.45 |
438.94 | 5.50 | 5.50 |
396.49 | 4.88 | 4.88 |
287.75 | 3.01 | 3.01 |
429.33 | 2.54 | 2.54 |
512.72 | 7.12 | 7.12 |
387.48 | 2.85 | 2.85 |
416.48 | 3.59 | 3.59 |
433.89 | 4.11 | 4.11 |
310.36 | 1.37 | 1.37 |
416.57 | 5.08 | 5.08 |
430.66 | 4.70 | 4.70 |
368.78 | 5.01 | 5.01 |
451.50 | 5.09 | 5.09 |
345.78 | 3.59 | 3.59 |
448.52 | 4.29 | 4.29 |
508.05 | 4.94 | 4.94 |
358.85 | 4.91 | 4.91 |
328.76 | 2.82 | 2.82 |
408.91 | 6.19 | 6.19 |
431.32 | 4.31 | 4.31 |
360.44 | 4.50 | 4.50 |
425.53 | 5.93 | 5.93 |
429.57 | 3.88 | 3.88 |
438.94 | 4.23 | 4.23 |
362.93 | 4.78 | 4.78 |
405.52 | 4.39 | 4.39 |
402.88 | 4.91 | 4.91 |
351.45 | 4.73 | 4.73 |
415.36 | 5.73 | 5.73 |
396.43 | 5.08 | 5.08 |
402.23 | 3.64 | 3.64 |
378.47 | 4.93 | 4.93 |
325.78 | 2.18 | 2.18 |
438.94 | 2.28 | 2.28 |
376.87 | 3.57 | 3.57 |
420.49 | 4.70 | 4.70 |
404.49 | 4.75 | 4.75 |
379.53 | 5.41 | 5.41 |
339.82 | 5.24 | 5.24 |
436.58 | 4.48 | 4.48 |
278.36 | 4.05 | 4.05 |
432.93 | 5.02 | 5.02 |
459.91 | 3.45 | 3.45 |
482.58 | 4.88 | 4.88 |
346.39 | 2.38 | 2.38 |
453.56 | 3.69 | 3.69 |
474.95 | 3.97 | 3.97 |
432.61 | 3.89 | 3.89 |
492.62 | 3.10 | 3.10 |
456.98 | 2.87 | 2.87 |
339.82 | 5.24 | 5.24 |
358.44 | 3.70 | 3.70 |
457.49 | 4.99 | 4.99 |
376.41 | 4.90 | 4.90 |
504.99 | 4.48 | 4.48 |
391.47 | 5.65 | 5.65 |
292.33 | 1.27 | 1.27 |
480.90 | 5.36 | 5.36 |
422.51 | 3.37 | 3.37 |
395.82 | 5.04 | 5.04 |
306.36 | 1.58 | 1.58 |
361.45 | 3.50 | 3.50 |
343.82 | 3.99 | 3.99 |
531.64 | 4.07 | 4.07 |
396.43 | 5.08 | 5.08 |
378.43 | 6.21 | 6.21 |
427.45 | 3.63 | 3.63 |
271.30 | 2.49 | 2.49 |
576.65 | 4.60 | 4.60 |
478.53 | 4.52 | 4.52 |
528.12 | 4.61 | 4.61 |
449.50 | 5.42 | 5.42 |
445.93 | 3.78 | 3.78 |
554.60 | 6.02 | 6.02 |
324.45 | 4.74 | 4.74 |
401.96 | 4.95 | 4.95 |
320.39 | 4.48 | 4.48 |
606.21 | 6.32 | 6.32 |
423.49 | 3.89 | 3.89 |
540.69 | 2.74 | 2.74 |
399.49 | 4.56 | 4.56 |
405.89 | 5.52 | 5.52 |
415.49 | 3.56 | 3.56 |
381.51 | 3.82 | 3.82 |
573.98 | 5.03 | 5.03 |
399.92 | 5.62 | 5.62 |
499.95 | 4.69 | 4.69 |
424.28 | 2.78 | 2.78 |
477.75 | 7.32 | 7.32 |
458.91 | 5.98 | 5.98 |
382.91 | 5.51 | 5.51 |
368.50 | 4.94 | 4.94 |
444.62 | 5.98 | 5.98 |
386.93 | 4.00 | 4.00 |
350.40 | 3.24 | 3.24 |
431.90 | 3.67 | 3.67 |
417.48 | 4.37 | 4.37 |
537.47 | 3.48 | 3.48 |
500.41 | 6.67 | 6.67 |
424.91 | 1.89 | 1.89 |
497.47 | 4.50 | 4.50 |
459.91 | 3.53 | 3.53 |
427.46 | 0.34 | 0.34 |
440.31 | 3.62 | 3.62 |
394.54 | 5.07 | 5.07 |
360.26 | 3.78 | 3.78 |
508.58 | 5.56 | 5.56 |
566.12 | 5.19 | 5.19 |
401.51 | 3.24 | 3.24 |
383.26 | 3.44 | 3.44 |
445.93 | 3.78 | 3.78 |
370.91 | 5.62 | 5.62 |
388.51 | 5.66 | 5.66 |
467.71 | 6.91 | 6.91 |
581.76 | 3.62 | 3.62 |
474.33 | 3.87 | 3.87 |
445.56 | 5.45 | 5.45 |
373.87 | 4.75 | 4.75 |
488.98 | 4.28 | 4.28 |
426.58 | 4.54 | 4.54 |
462.60 | 5.75 | 5.75 |
494.54 | 5.00 | 5.00 |
383.88 | 5.64 | 5.64 |
452.49 | 3.97 | 3.97 |
434.58 | 5.03 | 5.03 |
530.70 | 4.83 | 4.83 |
528.72 | 4.19 | 4.19 |
430.66 | 4.70 | 4.70 |
577.50 | 5.39 | 5.39 |
386.93 | 3.90 | 3.90 |
421.59 | 2.66 | 2.66 |
441.48 | 4.02 | 4.02 |
420.26 | 4.06 | 4.06 |
413.56 | 5.85 | 5.85 |
576.67 | 4.79 | 4.79 |
483.01 | 3.95 | 3.95 |
463.39 | 4.86 | 4.86 |
462.91 | 5.01 | 5.01 |
431.49 | 4.02 | 4.02 |
305.35 | 2.48 | 2.48 |
463.99 | 6.69 | 6.69 |
375.44 | 3.19 | 3.19 |
367.49 | 3.26 | 3.26 |
424.53 | 4.86 | 4.86 |
471.54 | 4.93 | 4.93 |
464.64 | 4.14 | 4.14 |
378.82 | 4.49 | 4.49 |
448.59 | 5.77 | 5.77 |
445.91 | 2.54 | 2.54 |
446.57 | 3.12 | 3.12 |
604.66 | 4.43 | 4.43 |
485.33 | 3.19 | 3.19 |
385.89 | 5.38 | 5.38 |
378.54 | 5.34 | 5.34 |
348.45 | 3.85 | 3.85 |
369.54 | 4.28 | 4.28 |
434.58 | 5.03 | 5.03 |
389.43 | 4.14 | 4.14 |
350.42 | 4.07 | 4.07 |
444.92 | 4.87 | 4.87 |
386.46 | 4.58 | 4.58 |
433.58 | 4.69 | 4.69 |
462.58 | 3.84 | 3.84 |
402.61 | 3.92 | 3.92 |
451.96 | 3.64 | 3.64 |
488.58 | 5.50 | 5.50 |
493.51 | 4.86 | 4.86 |
424.30 | 5.53 | 5.53 |
423.48 | 3.95 | 3.95 |
431.51 | 5.96 | 5.96 |
467.54 | 5.66 | 5.66 |
430.55 | 4.20 | 4.20 |
429.52 | 3.95 | 3.95 |
482.01 | 4.97 | 4.97 |
382.89 | 4.56 | 4.56 |
397.50 | 4.70 | 4.70 |
362.78 | 6.14 | 6.14 |
419.89 | 3.36 | 3.36 |
382.49 | 3.87 | 3.87 |
488.61 | 4.71 | 4.71 |
551.65 | 4.94 | 4.94 |
365.50 | 4.95 | 4.95 |
423.49 | 3.74 | 3.74 |
498.95 | 4.56 | 4.56 |
477.87 | 5.28 | 5.28 |
437.42 | 5.82 | 5.82 |
457.00 | 4.82 | 4.82 |
416.48 | 1.74 | 1.74 |
352.39 | 4.00 | 4.00 |
504.52 | 3.14 | 3.14 |
402.47 | 4.25 | 4.25 |
465.89 | 3.51 | 3.51 |
336.39 | 2.98 | 2.98 |
409.46 | 3.50 | 3.50 |
493.54 | 5.48 | 5.48 |
572.59 | 3.78 | 3.78 |
375.23 | 2.14 | 2.14 |
389.43 | 3.48 | 3.48 |
431.52 | 4.88 | 4.88 |
317.40 | 3.65 | 3.65 |
337.45 | 4.27 | 4.27 |
279.34 | 3.81 | 3.81 |
385.46 | 4.31 | 4.31 |
426.92 | 3.54 | 3.54 |
374.49 | 3.72 | 3.72 |
369.83 | 1.86 | 1.86 |
451.96 | 3.64 | 3.64 |
305.38 | 4.58 | 4.58 |
480.50 | 3.97 | 3.97 |
338.48 | 5.21 | 5.21 |
420.97 | 6.23 | 6.23 |
326.36 | 2.98 | 2.98 |
442.97 | 3.89 | 3.89 |
343.43 | 4.79 | 4.79 |
399.45 | 5.33 | 5.33 |
361.35 | 5.47 | 5.47 |
301.33 | 2.40 | 2.40 |
386.25 | 2.60 | 2.60 |
392.57 | 6.38 | 6.38 |
393.87 | 5.25 | 5.25 |
540.09 | 5.27 | 5.27 |
399.88 | 3.74 | 3.74 |
467.57 | 3.70 | 3.70 |
397.54 | 3.90 | 3.90 |
506.93 | 5.93 | 5.93 |
446.60 | 5.37 | 5.37 |
518.71 | 3.68 | 3.68 |
354.48 | 4.45 | 4.45 |
345.40 | 4.73 | 4.73 |
351.45 | 4.03 | 4.03 |
347.80 | 4.49 | 4.49 |
339.42 | 3.85 | 3.85 |
347.46 | 4.79 | 4.79 |
367.75 | 5.59 | 5.59 |
498.03 | 5.65 | 5.65 |
416.64 | 4.31 | 4.31 |
429.86 | 6.36 | 6.36 |
290.36 | 1.88 | 1.88 |
392.91 | 3.37 | 3.37 |
432.31 | 4.67 | 4.67 |
479.58 | 4.15 | 4.15 |
444.92 | 2.11 | 2.11 |
309.41 | 3.89 | 3.89 |
401.42 | 3.53 | 3.53 |
404.43 | 3.46 | 3.46 |
379.41 | 3.96 | 3.96 |
360.87 | 5.77 | 5.77 |
457.55 | 4.09 | 4.09 |
397.43 | 5.37 | 5.37 |
429.91 | 6.50 | 6.50 |
429.38 | 6.12 | 6.12 |
470.98 | 4.34 | 4.34 |
407.42 | 5.10 | 5.10 |
302.40 | 2.93 | 2.93 |
411.53 | 3.81 | 3.81 |
468.64 | 3.69 | 3.69 |
434.56 | 5.46 | 5.46 |
402.54 | 4.83 | 4.83 |
415.90 | 3.97 | 3.97 |
284.34 | 1.99 | 1.99 |
442.94 | 5.59 | 5.59 |
486.50 | 3.78 | 3.78 |
406.53 | 6.03 | 6.03 |
496.94 | 5.22 | 5.22 |
412.51 | 5.39 | 5.39 |
369.47 | 4.78 | 4.78 |
451.96 | 3.64 | 3.64 |
444.28 | 2.91 | 2.91 |
433.94 | 4.95 | 4.95 |
454.94 | 5.45 | 5.45 |
306.36 | 1.66 | 1.66 |
413.48 | 4.23 | 4.23 |
335.41 | 3.70 | 3.70 |
422.87 | 5.35 | 5.35 |
429.57 | 3.78 | 3.78 |
375.47 | 4.74 | 4.74 |
358.51 | 3.85 | 3.85 |
407.56 | 3.18 | 3.18 |
473.86 | 7.01 | 7.01 |
418.47 | 5.79 | 5.79 |
265.31 | 3.03 | 3.03 |
439.31 | 3.79 | 3.79 |
399.51 | 4.74 | 4.74 |
392.57 | 6.30 | 6.30 |
387.57 | 3.40 | 3.40 |
357.43 | 3.53 | 3.53 |
432.42 | 4.75 | 4.75 |
467.55 | 4.28 | 4.28 |
491.68 | 4.20 | 4.20 |
337.42 | 3.47 | 3.47 |
509.05 | 4.87 | 4.87 |
428.28 | 1.60 | 1.60 |
416.57 | 4.35 | 4.35 |
359.41 | 2.69 | 2.69 |
401.88 | 3.51 | 3.51 |
460.77 | 3.46 | 3.46 |
331.39 | 3.08 | 3.08 |
438.51 | 2.98 | 2.98 |