Basic Information
ID: ALA2114870
Type: Functional
Description: PubChem BioAssay. qHTS screen for small molecules that inhibit ELG1-dependent DNA repair: Hit Confirmation with 5FU Viability. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114870
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.76 | 4.04 | 4.04 |
| 506.47 | 2.32 | 2.32 |
| 560.64 | 2.41 | 2.41 |
| 298.32 | -0.84 | -0.84 |
| 462.93 | 5.49 | 5.49 |
| 262.30 | 1.25 | 1.25 |
| 373.46 | 3.03 | 3.03 |
| 466.54 | 4.35 | 4.35 |
| 336.42 | 3.12 | 3.12 |
| 442.55 | 3.80 | 3.80 |
| 284.30 | -1.27 | -1.27 |
| 409.07 | ||
| 507.98 | -0.79 | -0.79 |
| 393.45 | 3.41 | 3.41 |
| 383.68 | 5.34 | 5.34 |
| 1111.34 | ||
| 599.14 | 4.28 | 4.28 |
| 578.72 | 3.94 | 3.94 |
| 461.52 | 2.06 | 2.06 |
| 405.48 | 4.57 | 4.57 |
| 507.60 | 1.65 | 1.65 |
| 455.54 | 4.72 | 4.72 |
| 396.41 | 3.32 | 3.32 |
| 528.02 | 3.42 | 3.42 |
| 456.50 | 5.38 | 5.38 |
| 434.45 | 3.33 | 3.33 |
| 424.50 | 3.14 | 3.14 |
| 426.47 | 3.07 | 3.07 |
| 384.30 | 3.14 | 3.14 |
| 334.40 | 3.53 | 3.53 |
| 511.99 | 4.13 | 4.13 |
| 490.98 | 5.26 | 5.26 |
| 728.78 | -1.51 | -1.51 |
| 457.60 | 3.88 | 3.88 |
| 405.52 | 2.69 | 2.69 |
| 484.57 | 3.51 | 3.51 |
| 456.50 | 3.33 | 3.33 |
| 533.58 | 4.35 | 4.35 |
| 494.57 | 6.24 | 6.24 |
| 510.59 | 3.52 | 3.52 |
| 500.62 | 4.08 | 4.08 |
| 388.52 | 3.35 | 3.35 |
| 379.47 | 2.64 | 2.64 |
| 491.50 | 4.34 | 4.34 |
| 418.50 | 1.97 | 1.97 |
| 520.54 | 2.39 | 2.39 |
| 487.62 | 3.97 | 3.97 |
| 492.53 | 2.64 | 2.64 |
| 408.53 | 5.42 | 5.42 |
| 485.01 | 4.87 | 4.87 |
| 338.45 | 3.22 | 3.22 |
| 443.96 | 4.86 | 4.86 |
| 487.66 | 3.79 | 3.79 |
| 353.41 | 2.72 | 2.72 |
| 462.50 | 5.31 | 5.31 |
| 534.69 | 3.11 | 3.11 |
| 445.57 | 2.81 | 2.81 |
| 308.26 | -1.04 | -1.04 |
| 411.51 | 3.27 | 3.27 |
| 550.65 | 0.75 | 0.75 |
| 466.58 | 2.66 | 2.66 |
| 513.57 | 3.33 | 3.33 |
| 489.92 | 4.98 | 4.98 |
| 438.96 | 4.37 | 4.37 |
| 471.62 | 4.12 | 4.12 |
| 470.57 | 3.98 | 3.98 |
| 493.99 | 3.57 | 3.57 |
| 485.57 | 4.89 | 4.89 |
| 791.08 | 5.88 | 5.88 |
| 433.60 | 6.02 | 6.02 |
| 400.50 | 2.99 | 2.99 |
| 573.63 | 5.25 | 5.25 |
| 412.91 | 4.43 | 4.43 |
| 330.32 | 1.55 | 1.55 |
| 407.43 | 3.61 | 3.61 |
| 427.34 | 2.25 | 2.25 |
| 423.22 | 4.26 | 4.26 |
| 473.47 | 0.96 | 0.96 |
| 515.41 | 3.67 | 3.67 |
| 415.52 | 3.44 | 3.44 |
| 450.42 | 3.34 | 3.34 |
| 454.87 | 4.06 | 4.06 |
| 414.53 | 4.63 | 4.63 |
| 382.39 | 4.59 | 4.59 |
| 458.56 | 3.64 | 3.64 |
| 395.53 | 3.93 | 3.93 |
| 406.45 | 2.95 | 2.95 |
| 452.58 | 3.76 | 3.76 |
| 496.52 | 4.24 | 4.24 |
| 466.22 | 4.73 | 4.73 |
| 365.37 | 2.03 | 2.03 |
| 334.33 | 4.71 | 4.71 |
| 443.43 | 4.20 | 4.20 |
| 428.45 | 3.99 | 3.99 |
| 460.51 | 2.79 | 2.79 |
| 421.57 | 5.16 | 5.16 |
| 410.43 | 4.14 | 4.14 |
| 408.89 | 1.30 | 1.30 |
| 401.43 | 1.51 | 1.51 |
| 347.83 | 4.63 | 4.63 |
| 495.62 | 3.79 | 3.79 |
| 468.61 | 4.24 | 4.24 |
| 428.51 | 2.93 | 2.93 |
| 494.57 | 3.00 | 3.00 |
| 399.44 | 3.02 | 3.02 |
| 501.51 | 5.07 | 5.07 |
| 399.45 | 3.63 | 3.63 |
| 356.35 | 2.95 | 2.95 |
| 507.50 | 4.07 | 4.07 |
| 338.46 | 4.02 | 4.02 |
| 489.96 | 5.28 | 5.28 |
| 488.61 | 4.41 | 4.41 |
| 404.50 | 1.90 | 1.90 |
| 460.53 | 4.18 | 4.18 |
| 419.48 | 3.43 | 3.43 |
| 406.49 | 3.02 | 3.02 |
| 394.33 | 4.66 | 4.66 |
| 434.49 | 2.79 | 2.79 |
| 478.55 | 2.39 | 2.39 |
| 462.48 | 4.73 | 4.73 |
| 544.51 | 3.08 | 3.08 |
| 312.78 | 2.22 | 2.22 |
| 548.67 | 2.29 | 2.29 |
| 335.36 | 3.75 | 3.75 |
| 474.51 | 5.20 | 5.20 |
| 425.55 | 3.81 | 3.81 |
| 523.62 | 3.38 | 3.38 |
| 621.53 | 4.95 | 4.95 |
| 339.27 | 3.59 | 3.59 |
| 446.59 | 3.79 | 3.79 |
| 310.83 | 3.11 | 3.11 |
| 544.97 | 3.92 | 3.92 |
| 392.45 | 2.88 | 2.88 |
| 479.58 | 2.42 | 2.42 |
| 474.51 | 3.66 | 3.66 |
| 405.51 | 3.11 | 3.11 |
| 464.47 | 1.99 | 1.99 |
| 489.65 | 4.64 | 4.64 |
| 378.39 | 2.18 | 2.18 |
| 420.58 | 3.97 | 3.97 |
| 383.40 | 5.02 | 5.02 |
| 420.42 | 4.55 | 4.55 |
| 1009.18 | ||
| 408.41 | 3.06 | 3.06 |
| 382.90 | 3.92 | 3.92 |
| 382.38 | 2.83 | 2.83 |
| 468.58 | 3.83 | 3.83 |
| 478.56 | 4.15 | 4.15 |
| 417.47 | 3.18 | 3.18 |
| 380.47 | 4.60 | 4.60 |
| 438.50 | 3.75 | 3.75 |
| 474.59 | 3.72 | 3.72 |
| 474.51 | 4.67 | 4.67 |
| 445.46 | 7.16 | 7.16 |
| 410.43 | 3.06 | 3.06 |
| 342.36 | 1.73 | 1.73 |
| 429.55 | 4.18 | 4.18 |
| 328.38 | 4.44 | 4.44 |
| 375.43 | 3.18 | 3.18 |
| 523.59 | 4.07 | 4.07 |
| 520.61 | 6.96 | 6.96 |
| 477.57 | 1.64 | 1.64 |
| 426.49 | 2.72 | 2.72 |
| 443.55 | 4.03 | 4.03 |
| 566.65 | 4.16 | 4.16 |
| 396.40 | 4.75 | 4.75 |
| 526.64 | 5.25 | 5.25 |
| 428.54 | 3.10 | 3.10 |
| 448.53 | 3.19 | 3.19 |
| 407.52 | 2.35 | 2.35 |
| 399.50 | 4.42 | 4.42 |
| 433.49 | 2.18 | 2.18 |
| 453.50 | 1.63 | 1.63 |
| 397.43 | 1.93 | 1.93 |
| 467.60 | 3.44 | 3.44 |
| 336.35 | 1.92 | 1.92 |
| 389.81 | 3.99 | 3.99 |
| 435.49 | 0.93 | 0.93 |
| 488.65 | 4.19 | 4.19 |
| 430.57 | 3.19 | 3.19 |
| 333.35 | 3.34 | 3.34 |
| 493.56 | 4.53 | 4.53 |
| 404.48 | 5.02 | 5.02 |
| 450.54 | 3.43 | 3.43 |
| 491.49 | 4.70 | 4.70 |
| 397.31 | 3.14 | 3.14 |
| 531.63 | 5.04 | 5.04 |
| 492.60 | 4.15 | 4.15 |
| 415.90 | 4.21 | 4.21 |
| 462.93 | 5.49 | 5.49 |
| 409.44 | 3.46 | 3.46 |
| 581.65 | 2.68 | 2.68 |
| 398.51 | 4.56 | 4.56 |
| 434.51 | 2.58 | 2.58 |
| 480.63 | 3.98 | 3.98 |
| 444.63 | 4.11 | 4.11 |
| 422.55 | 3.87 | 3.87 |
| 447.37 | 3.98 | 3.98 |
| 531.61 | 5.15 | 5.15 |
| 386.45 | 3.02 | 3.02 |
| 416.54 | 3.89 | 3.89 |
| 548.67 | 2.43 | 2.43 |
| 344.44 | 2.69 | 2.69 |
| 494.64 | 2.74 | 2.74 |
| 443.88 | 3.90 | 3.90 |
| 356.43 | 3.01 | 3.01 |
| 425.55 | 3.94 | 3.94 |
| 375.45 | 2.97 | 2.97 |
| 555.42 | 7.06 | 7.06 |
| 470.00 | 4.18 | 4.18 |
| 462.55 | 3.58 | 3.58 |
| 386.46 | 4.36 | 4.36 |
| 492.59 | 4.46 | 4.46 |
| 487.65 | 3.25 | 3.25 |
| 417.48 | 2.78 | 2.78 |
| 350.21 | 3.40 | 3.40 |
| 443.45 | 3.56 | 3.56 |
| 404.39 | 4.37 | 4.37 |
| 478.50 | 2.17 | 2.17 |
| 472.54 | 4.32 | 4.32 |
| 586.68 | -1.44 | -1.44 |
| 412.48 | 3.69 | 3.69 |
| 554.69 | 5.76 | 5.76 |
| 253.26 | 2.20 | 2.20 |
| 523.64 | 2.59 | 2.59 |
| 388.54 | 3.08 | 3.08 |
| 495.54 | 4.48 | 4.48 |
| 452.56 | 2.35 | 2.35 |
| 540.01 | 5.29 | 5.29 |
| 384.38 | 3.22 | 3.22 |
| 272.26 | 3.15 | 3.15 |
| 452.46 | 2.59 | 2.59 |
| 570.55 | 3.05 | 3.05 |
| 435.48 | 3.41 | 3.41 |
| 345.79 | 4.10 | 4.10 |
| 416.36 | 3.95 | 3.95 |
| 478.65 | 4.65 | 4.65 |
| 462.44 | 4.97 | 4.97 |
| 469.56 | 3.81 | 3.81 |
| 427.55 | 3.70 | 3.70 |
| 429.55 | 4.18 | 4.18 |
| 431.50 | 2.69 | 2.69 |
| 292.72 | 3.10 | 3.10 |
| 501.65 | 4.36 | 4.36 |
| 572.68 | 4.76 | 4.76 |
| 472.59 | 3.95 | 3.95 |
| 525.68 | 4.42 | 4.42 |
| 423.92 | 2.03 | 2.03 |
| 579.62 | 4.62 | 4.62 |
| 366.37 | 2.53 | 2.53 |
| 614.79 | 4.78 | 4.78 |
| 480.52 | 4.84 | 4.84 |
| 388.52 | 2.82 | 2.82 |
| 454.96 | 4.07 | 4.07 |
| 613.64 | 5.73 | 5.73 |
| 667.71 | 5.63 | 5.63 |
| 630.62 | 2.15 | 2.15 |
| 510.61 | 3.65 | 3.65 |
| 529.49 | 3.28 | 3.28 |
| 504.62 | 4.30 | 4.30 |
| 478.50 | 2.30 | 2.30 |
| 600.73 | 5.26 | 5.26 |
| 487.38 | 5.15 | 5.15 |
| 526.97 | 4.31 | 4.31 |
| 386.37 | 2.93 | 2.93 |
| 500.52 | 2.19 | 2.19 |
| 657.65 | 5.46 | 5.46 |
| 396.49 | 3.94 | 3.94 |
| 459.54 | 3.69 | 3.69 |
| 458.58 | 2.03 | 2.03 |
| 475.54 | 6.73 | 6.73 |
| 440.52 | 2.48 | 2.48 |
| 501.58 | 5.53 | 5.53 |
| 450.45 | 1.68 | 1.68 |
| 653.53 | 7.01 | 7.01 |
| 405.46 | 2.91 | 2.91 |
| 454.50 | 3.05 | 3.05 |
| 480.57 | 3.43 | 3.43 |
| 548.64 | 5.93 | 5.93 |
| 612.65 | 5.27 | 5.27 |
| 618.58 | 5.37 | 5.37 |
| 577.66 | 4.51 | 4.51 |
| 454.52 | 3.97 | 3.97 |
| 548.74 | 5.25 | 5.25 |
| 572.68 | 4.76 | 4.76 |
| 473.25 | 3.10 | 3.10 |
| 800.92 | 5.41 | 5.41 |
| 455.51 | 3.66 | 3.66 |
| 446.51 | 4.96 | 4.96 |
| 586.70 | 5.15 | 5.15 |
| 758.84 | 4.24 | 4.24 |
| 524.66 | 3.26 | 3.26 |
| 489.62 | 3.13 | 3.13 |
| 475.61 | 3.13 | 3.13 |
| 380.45 | 2.04 | 2.04 |
| 440.57 | 4.12 | 4.12 |
| 474.11 | 3.81 | 3.81 |
| 398.53 | 4.63 | 4.63 |
| 459.63 | 3.57 | 3.57 |
| 366.43 | 3.14 | 3.14 |
| 394.43 | 4.34 | 4.34 |
| 401.50 | 2.96 | 2.96 |
| 357.40 | 2.86 | 2.86 |
| 780.95 | 2.22 | 2.22 |
| 444.52 | 2.83 | 2.83 |
| 411.87 | 5.37 | 5.37 |
| 485.53 | 4.20 | 4.20 |
| 529.56 | 4.11 | 4.11 |
| 387.42 | 2.87 | 2.87 |
| 482.92 | 4.66 | 4.66 |
| 569.71 | 3.03 | 3.03 |
| 601.41 | 4.34 | 4.34 |
| 435.49 | 4.56 | 4.56 |
| 435.49 | 4.56 | 4.56 |
| 475.50 | 4.14 | 4.14 |
| 430.46 | 2.83 | 2.83 |
| 517.56 | 4.04 | 4.04 |
| 455.56 | 3.15 | 3.15 |
| 455.56 | 2.98 | 2.98 |
| 410.43 | 3.58 | 3.58 |
| 450.51 | 3.82 | 3.82 |
| 457.49 | 3.63 | 3.63 |
| 493.57 | 3.96 | 3.96 |