ID: ALA2114872
Type: Functional
Description: PubChem BioAssay. qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation using MMS Stimulated ELG1. (Class of assay: confirmatory)
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA2114872
Potency
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
398.40 | 3.70 | 3.70 |
315.76 | 4.04 | 4.04 |
506.47 | 2.32 | 2.32 |
560.64 | 2.41 | 2.41 |
298.32 | -0.84 | -0.84 |
736.94 | 6.02 | 6.02 |
392.15 | -0.77 | -0.77 |
265.32 | 3.25 | 3.25 |
262.30 | 1.25 | 1.25 |
366.41 | 1.12 | 1.12 |
265.31 | 0.50 | 0.50 |
224.26 | 3.03 | 3.03 |
325.35 | -1.74 | -1.74 |
320.38 | 3.37 | 3.37 |
373.46 | 3.03 | 3.03 |
466.54 | 4.35 | 4.35 |
336.42 | 3.12 | 3.12 |
322.39 | 3.06 | 3.06 |
442.55 | 3.80 | 3.80 |
244.21 | -3.17 | -3.17 |
284.30 | -1.27 | -1.27 |
409.07 | ||
307.38 | 3.03 | 3.03 |
507.98 | -0.79 | -0.79 |
393.45 | 3.41 | 3.41 |
383.68 | 5.34 | 5.34 |
1111.34 | ||
266.23 | 2.07 | 2.07 |
578.72 | 3.94 | 3.94 |
461.52 | 2.06 | 2.06 |
477.59 | 3.26 | 3.26 |
431.53 | 2.58 | 2.58 |
420.44 | 3.75 | 3.75 |
405.48 | 4.57 | 4.57 |
507.60 | 1.65 | 1.65 |
344.81 | 3.39 | 3.39 |
397.78 | 3.43 | 3.43 |
482.63 | 4.16 | 4.16 |
528.02 | 3.42 | 3.42 |
456.50 | 5.38 | 5.38 |
259.31 | 3.44 | 3.44 |
361.42 | 4.60 | 4.60 |
323.38 | 2.71 | 2.71 |
356.82 | 3.12 | 3.12 |
290.39 | 2.49 | 2.49 |
387.32 | 3.96 | 3.96 |
472.54 | 3.37 | 3.37 |
534.61 | 3.09 | 3.09 |
431.90 | 3.47 | 3.47 |
426.47 | 3.07 | 3.07 |
332.45 | 4.12 | 4.12 |
466.58 | 4.49 | 4.49 |
478.55 | 2.57 | 2.57 |
467.62 | 4.66 | 4.66 |
437.55 | 4.47 | 4.47 |
309.20 | 4.24 | 4.24 |
480.57 | 2.62 | 2.62 |
257.25 | 1.66 | 1.66 |
271.35 | 3.31 | 3.31 |
384.30 | 3.14 | 3.14 |
460.54 | 2.49 | 2.49 |
334.40 | 3.53 | 3.53 |
511.99 | 4.13 | 4.13 |
490.98 | 5.26 | 5.26 |
728.78 | -1.51 | -1.51 |
465.57 | 1.79 | 1.79 |
340.34 | 2.13 | 2.13 |
457.60 | 3.88 | 3.88 |
281.34 | 4.32 | 4.32 |
461.54 | 4.57 | 4.57 |
320.36 | 2.70 | 2.70 |
484.57 | 3.51 | 3.51 |
418.41 | 1.04 | 1.04 |
320.39 | 4.10 | 4.10 |
460.52 | 3.10 | 3.10 |
429.52 | 3.17 | 3.17 |
519.58 | 4.06 | 4.06 |
266.14 | 3.21 | 3.21 |
344.48 | 3.92 | 3.92 |
510.59 | 3.52 | 3.52 |
333.39 | 2.60 | 2.60 |
327.80 | 3.35 | 3.35 |
379.47 | 2.64 | 2.64 |
448.64 | 5.33 | 5.33 |
491.50 | 4.34 | 4.34 |
432.54 | 3.37 | 3.37 |
418.50 | 1.97 | 1.97 |
426.44 | 5.62 | 5.62 |
460.94 | 4.21 | 4.21 |
520.54 | 2.39 | 2.39 |
487.62 | 3.97 | 3.97 |
380.40 | 3.02 | 3.02 |
492.53 | 2.64 | 2.64 |
290.75 | 3.37 | 3.37 |
545.67 | 4.42 | 4.42 |
443.96 | 4.86 | 4.86 |
487.66 | 3.79 | 3.79 |
534.69 | 3.11 | 3.11 |
445.57 | 2.81 | 2.81 |
308.26 | -1.04 | -1.04 |
388.49 | 3.43 | 3.43 |
550.65 | 0.75 | 0.75 |
494.57 | 3.34 | 3.34 |
519.40 | 3.75 | 3.75 |
466.58 | 2.66 | 2.66 |
352.78 | 3.52 | 3.52 |
326.36 | 4.01 | 4.01 |
513.57 | 3.33 | 3.33 |
438.96 | 4.37 | 4.37 |
471.62 | 4.12 | 4.12 |
443.57 | 3.34 | 3.34 |
470.57 | 3.98 | 3.98 |
493.99 | 3.57 | 3.57 |
237.26 | 1.35 | 1.35 |
485.57 | 4.89 | 4.89 |
791.08 | 5.88 | 5.88 |
251.29 | 1.74 | 1.74 |
433.60 | 6.02 | 6.02 |
573.63 | 5.25 | 5.25 |
592.70 | 4.32 | 4.32 |
366.46 | 3.14 | 3.14 |
412.91 | 4.43 | 4.43 |
302.19 | 3.36 | 3.36 |
279.34 | 3.29 | 3.29 |
330.32 | 1.55 | 1.55 |
407.43 | 3.61 | 3.61 |
336.33 | 3.00 | 3.00 |
390.42 | 1.20 | 1.20 |
454.50 | 3.72 | 3.72 |
427.34 | 2.25 | 2.25 |
430.51 | 4.00 | 4.00 |
423.22 | 4.26 | 4.26 |
378.48 | 4.27 | 4.27 |
345.36 | 0.96 | 0.96 |
473.47 | 0.96 | 0.96 |
515.41 | 3.67 | 3.67 |
475.55 | 3.08 | 3.08 |
454.87 | 4.06 | 4.06 |
414.53 | 4.63 | 4.63 |
400.82 | 3.44 | 3.44 |
382.39 | 4.59 | 4.59 |
377.43 | 3.19 | 3.19 |
458.56 | 3.64 | 3.64 |
360.48 | 3.68 | 3.68 |
379.46 | 4.64 | 4.64 |
428.60 | 2.62 | 2.62 |
484.60 | 3.93 | 3.93 |
406.45 | 2.95 | 2.95 |
288.30 | 1.97 | 1.97 |
365.37 | 2.03 | 2.03 |
334.33 | 4.71 | 4.71 |
319.29 | 4.14 | 4.14 |
363.33 | 2.77 | 2.77 |
426.56 | 3.54 | 3.54 |
443.43 | 4.20 | 4.20 |
264.33 | 2.72 | 2.72 |
236.30 | 1.04 | 1.04 |
364.35 | 4.18 | 4.18 |
219.29 | 1.93 | 1.93 |
441.55 | 3.87 | 3.87 |
542.46 | 5.72 | 5.72 |
334.42 | 3.93 | 3.93 |
421.57 | 5.16 | 5.16 |
494.59 | 3.26 | 3.26 |
410.43 | 4.14 | 4.14 |
270.36 | 3.05 | 3.05 |
322.44 | 3.19 | 3.19 |
543.67 | 2.96 | 2.96 |
501.54 | 4.39 | 4.39 |
235.37 | 3.12 | 3.12 |
401.43 | 1.51 | 1.51 |
347.83 | 4.63 | 4.63 |
495.62 | 3.79 | 3.79 |
315.40 | 3.36 | 3.36 |
332.36 | 3.33 | 3.33 |
494.57 | 3.00 | 3.00 |
399.44 | 3.02 | 3.02 |
501.51 | 5.07 | 5.07 |
267.32 | 0.99 | 0.99 |
399.45 | 3.63 | 3.63 |
428.44 | 4.03 | 4.03 |
312.38 | 4.74 | 4.74 |
296.30 | 3.23 | 3.23 |
440.53 | 5.01 | 5.01 |
396.44 | 3.78 | 3.78 |
338.46 | 4.02 | 4.02 |
489.96 | 5.28 | 5.28 |
404.50 | 1.90 | 1.90 |
460.53 | 4.18 | 4.18 |
458.02 | 2.80 | 2.80 |
539.61 | 3.01 | 3.01 |
483.57 | 3.28 | 3.28 |
355.39 | 3.62 | 3.62 |
406.49 | 3.02 | 3.02 |
319.82 | 3.81 | 3.81 |
434.49 | 2.79 | 2.79 |
382.42 | 5.02 | 5.02 |
341.42 | 1.61 | 1.61 |
478.55 | 2.39 | 2.39 |
480.61 | 5.04 | 5.04 |
544.51 | 3.08 | 3.08 |
306.37 | 3.65 | 3.65 |
474.52 | 4.21 | 4.21 |
312.78 | 2.22 | 2.22 |
548.67 | 2.29 | 2.29 |
387.87 | 2.23 | 2.23 |
364.38 | 2.16 | 2.16 |
335.36 | 3.75 | 3.75 |
392.43 | 5.06 | 5.06 |
480.60 | 5.10 | 5.10 |
474.51 | 5.20 | 5.20 |
482.51 | 3.56 | 3.56 |
379.41 | 4.74 | 4.74 |
346.41 | 2.40 | 2.40 |
431.49 | 3.45 | 3.45 |
425.55 | 3.81 | 3.81 |
523.62 | 3.38 | 3.38 |
418.55 | 3.97 | 3.97 |
420.51 | 5.37 | 5.37 |
276.34 | 3.72 | 3.72 |
389.46 | 2.16 | 2.16 |
353.38 | 2.91 | 2.91 |
621.53 | 4.95 | 4.95 |
547.69 | 4.79 | 4.79 |
371.26 | 2.64 | 2.64 |
323.61 | 5.43 | 5.43 |
339.27 | 3.59 | 3.59 |
340.38 | 3.87 | 3.87 |
446.59 | 3.79 | 3.79 |
337.38 | 3.47 | 3.47 |
267.34 | 3.02 | 3.02 |
353.39 | 3.02 | 3.02 |
310.83 | 3.11 | 3.11 |
335.27 | 4.87 | 4.87 |
494.57 | 3.00 | 3.00 |
459.54 | 2.21 | 2.21 |
424.55 | 2.76 | 2.76 |
392.45 | 2.88 | 2.88 |
309.39 | 3.13 | 3.13 |
362.41 | 2.12 | 2.12 |
479.58 | 2.42 | 2.42 |
474.51 | 3.66 | 3.66 |
410.43 | 2.72 | 2.72 |
408.45 | 4.51 | 4.51 |
405.51 | 3.11 | 3.11 |
464.47 | 1.99 | 1.99 |
489.65 | 4.64 | 4.64 |
420.92 | 2.50 | 2.50 |
399.49 | 4.02 | 4.02 |
375.35 | 3.44 | 3.44 |
378.39 | 2.18 | 2.18 |
420.58 | 3.97 | 3.97 |
383.40 | 5.02 | 5.02 |
420.42 | 4.55 | 4.55 |
384.53 | 3.32 | 3.32 |
410.27 | 4.03 | 4.03 |
387.48 | 3.95 | 3.95 |
447.72 | 5.07 | 5.07 |
1009.18 | ||
267.28 | 3.55 | 3.55 |
374.39 | 1.80 | 1.80 |
408.41 | 3.06 | 3.06 |
367.86 | 2.77 | 2.77 |
431.53 | 2.12 | 2.12 |
333.39 | 4.39 | 4.39 |
359.30 | 4.40 | 4.40 |
333.36 | 3.99 | 3.99 |
382.90 | 3.92 | 3.92 |
410.42 | 3.71 | 3.71 |
428.54 | 3.63 | 3.63 |
326.81 | 2.61 | 2.61 |
495.01 | 4.64 | 4.64 |
352.51 | 4.38 | 4.38 |
417.47 | 3.18 | 3.18 |
380.47 | 4.60 | 4.60 |
438.50 | 3.75 | 3.75 |
305.34 | 2.54 | 2.54 |
474.59 | 3.72 | 3.72 |
474.51 | 4.67 | 4.67 |
445.46 | 7.16 | 7.16 |
343.48 | 3.97 | 3.97 |
410.43 | 3.06 | 3.06 |
342.36 | 1.73 | 1.73 |
512.63 | 5.53 | 5.53 |
429.55 | 4.18 | 4.18 |
328.38 | 4.44 | 4.44 |
375.43 | 3.18 | 3.18 |
402.46 | 4.35 | 4.35 |
423.49 | 4.16 | 4.16 |
405.44 | 4.03 | 4.03 |
295.34 | 3.86 | 3.86 |
426.32 | 2.82 | 2.82 |
523.59 | 4.07 | 4.07 |
329.81 | 4.35 | 4.35 |
477.57 | 1.64 | 1.64 |
257.29 | 2.19 | 2.19 |
426.49 | 2.72 | 2.72 |
443.55 | 4.03 | 4.03 |
566.65 | 4.16 | 4.16 |
368.43 | 3.35 | 3.35 |
429.86 | 2.59 | 2.59 |
396.40 | 4.75 | 4.75 |
455.50 | 4.24 | 4.24 |
295.35 | 2.53 | 2.53 |
526.64 | 5.25 | 5.25 |
544.61 | 2.92 | 2.92 |
432.57 | 3.72 | 3.72 |
485.59 | 4.01 | 4.01 |
428.54 | 3.10 | 3.10 |
448.53 | 3.19 | 3.19 |
407.52 | 2.35 | 2.35 |
399.50 | 4.42 | 4.42 |
473.62 | 4.17 | 4.17 |
277.27 | 1.10 | 1.10 |
383.45 | 4.40 | 4.40 |
447.63 | 4.60 | 4.60 |
419.49 | 4.00 | 4.00 |
406.51 | 1.50 | 1.50 |
404.40 | 4.16 | 4.16 |
453.50 | 1.63 | 1.63 |
397.43 | 1.93 | 1.93 |
467.60 | 3.44 | 3.44 |
336.35 | 1.92 | 1.92 |
389.81 | 3.99 | 3.99 |
514.61 | 4.11 | 4.11 |
362.41 | 2.62 | 2.62 |
305.39 | 2.44 | 2.44 |
476.58 | 2.35 | 2.35 |
488.65 | 4.19 | 4.19 |
271.36 | 4.36 | 4.36 |
333.35 | 3.34 | 3.34 |
475.50 | 4.53 | 4.53 |
373.68 | 1.51 | 1.51 |
450.54 | 3.43 | 3.43 |
386.41 | 4.02 | 4.02 |
451.48 | 5.10 | 5.10 |
431.49 | 5.39 | 5.39 |
431.49 | 3.31 | 3.31 |
424.43 | 3.90 | 3.90 |
326.79 | 3.79 | 3.79 |
437.74 | 4.85 | 4.85 |
356.42 | 2.64 | 2.64 |
442.59 | 2.43 | 2.43 |
531.63 | 5.04 | 5.04 |
494.64 | 5.35 | 5.35 |
455.55 | 2.40 | 2.40 |
492.60 | 4.15 | 4.15 |
415.90 | 4.21 | 4.21 |
329.40 | 3.13 | 3.13 |
462.93 | 5.49 | 5.49 |
578.78 | 4.76 | 4.76 |
409.44 | 3.46 | 3.46 |
309.44 | 4.15 | 4.15 |
415.49 | 1.91 | 1.91 |
402.50 | 4.39 | 4.39 |
342.40 | 3.84 | 3.84 |
581.65 | 2.68 | 2.68 |
312.31 | 3.48 | 3.48 |
398.51 | 4.56 | 4.56 |
480.63 | 3.98 | 3.98 |
422.55 | 3.87 | 3.87 |
531.61 | 5.15 | 5.15 |
386.45 | 3.02 | 3.02 |
416.54 | 3.89 | 3.89 |
548.67 | 2.43 | 2.43 |
410.42 | 3.71 | 3.71 |
494.64 | 2.74 | 2.74 |
443.88 | 3.90 | 3.90 |
324.43 | 1.96 | 1.96 |
303.79 | 3.91 | 3.91 |
331.46 | 1.49 | 1.49 |
574.63 | 2.52 | 2.52 |
391.54 | 3.22 | 3.22 |
390.78 | 2.30 | 2.30 |
399.52 | 3.09 | 3.09 |
392.88 | 3.74 | 3.74 |
337.38 | 4.08 | 4.08 |
436.53 | 2.80 | 2.80 |
412.54 | 3.55 | 3.55 |
238.29 | 2.82 | 2.82 |
462.55 | 3.58 | 3.58 |
386.46 | 4.36 | 4.36 |
492.04 | 2.93 | 2.93 |
378.90 | 4.01 | 4.01 |
487.65 | 3.25 | 3.25 |
582.69 | 3.03 | 3.03 |
440.55 | 3.16 | 3.16 |
417.48 | 2.78 | 2.78 |
417.56 | 3.16 | 3.16 |
478.50 | 2.17 | 2.17 |
472.54 | 4.32 | 4.32 |
586.68 | -1.44 | -1.44 |
412.48 | 3.69 | 3.69 |
368.41 | 2.72 | 2.72 |
554.69 | 5.76 | 5.76 |
253.26 | 2.20 | 2.20 |
495.62 | 3.43 | 3.43 |
467.57 | 2.81 | 2.81 |
518.53 | 2.79 | 2.79 |
323.35 | 3.04 | 3.04 |
304.37 | 2.75 | 2.75 |
386.34 | 4.78 | 4.78 |
495.54 | 4.48 | 4.48 |
558.56 | 5.83 | 5.83 |
452.56 | 2.35 | 2.35 |
497.58 | 5.89 | 5.89 |
540.01 | 5.29 | 5.29 |
248.71 | 3.03 | 3.03 |
384.38 | 3.22 | 3.22 |
272.26 | 3.15 | 3.15 |
452.46 | 2.59 | 2.59 |
439.56 | 2.37 | 2.37 |
432.55 | 4.24 | 4.24 |
435.48 | 3.41 | 3.41 |
497.00 | 4.09 | 4.09 |
384.36 | 2.93 | 2.93 |
416.36 | 3.95 | 3.95 |
237.26 | 1.35 | 1.35 |
462.44 | 4.97 | 4.97 |
472.50 | 4.37 | 4.37 |
469.56 | 3.81 | 3.81 |
427.55 | 3.70 | 3.70 |
359.40 | 3.75 | 3.75 |
382.29 | 3.80 | 3.80 |
431.50 | 2.69 | 2.69 |
292.72 | 3.10 | 3.10 |
744.81 | 3.85 | 3.85 |
501.65 | 4.36 | 4.36 |
370.45 | 2.54 | 2.54 |
572.68 | 4.76 | 4.76 |
578.71 | 4.11 | 4.11 |
472.59 | 3.95 | 3.95 |
647.69 | 3.54 | 3.54 |
525.68 | 4.42 | 4.42 |
772.86 | 4.63 | 4.63 |
480.52 | 4.84 | 4.84 |
388.52 | 2.82 | 2.82 |
486.49 | 1.80 | 1.80 |
454.96 | 4.07 | 4.07 |
396.45 | 1.27 | 1.27 |
613.64 | 5.73 | 5.73 |
542.67 | 2.94 | 2.94 |
630.62 | 2.15 | 2.15 |
510.61 | 3.65 | 3.65 |
529.49 | 3.28 | 3.28 |
504.62 | 4.30 | 4.30 |
583.44 | 3.88 | 3.88 |
369.47 | 4.08 | 4.08 |
448.57 | 4.42 | 4.42 |
600.73 | 5.26 | 5.26 |
559.13 | 3.70 | 3.70 |
422.40 | 3.63 | 3.63 |
407.49 | 1.09 | 1.09 |
542.60 | 3.19 | 3.19 |
347.40 | 1.17 | 1.17 |
526.97 | 4.31 | 4.31 |
510.63 | 2.53 | 2.53 |
390.42 | 2.42 | 2.42 |
500.52 | 2.19 | 2.19 |
487.56 | 2.31 | 2.31 |
396.49 | 3.94 | 3.94 |
459.54 | 3.69 | 3.69 |
439.59 | 2.40 | 2.40 |
475.54 | 6.73 | 6.73 |
440.52 | 2.48 | 2.48 |
445.54 | 1.32 | 1.32 |
425.58 | 2.32 | 2.32 |
653.53 | 7.01 | 7.01 |
454.50 | 3.05 | 3.05 |
548.64 | 5.93 | 5.93 |
348.36 | 1.79 | 1.79 |
466.54 | 3.30 | 3.30 |
367.41 | 4.09 | 4.09 |
618.58 | 5.37 | 5.37 |
577.66 | 4.51 | 4.51 |
548.74 | 5.25 | 5.25 |
572.68 | 4.76 | 4.76 |
344.87 | 3.76 | 3.76 |
463.29 | 1.40 | 1.40 |
473.25 | 3.10 | 3.10 |
800.92 | 5.41 | 5.41 |
356.40 | 3.27 | 3.27 |
455.51 | 3.66 | 3.66 |
446.51 | 4.96 | 4.96 |
586.70 | 5.15 | 5.15 |
758.84 | 4.24 | 4.24 |
524.66 | 3.26 | 3.26 |
370.43 | 3.66 | 3.66 |
489.62 | 3.13 | 3.13 |
475.61 | 3.13 | 3.13 |
380.45 | 2.04 | 2.04 |
474.11 | 3.81 | 3.81 |
398.53 | 4.63 | 4.63 |
459.63 | 3.57 | 3.57 |
503.15 | 4.59 | 4.59 |
366.43 | 3.14 | 3.14 |
394.43 | 4.34 | 4.34 |
379.21 | 2.94 | 2.94 |
401.50 | 2.96 | 2.96 |
357.40 | 2.86 | 2.86 |
389.46 | 3.64 | 3.64 |
780.95 | 2.22 | 2.22 |
444.52 | 2.83 | 2.83 |
411.87 | 5.37 | 5.37 |
529.56 | 4.11 | 4.11 |
387.42 | 2.87 | 2.87 |
447.37 | 2.31 | 2.31 |
350.33 | 1.68 | 1.68 |
482.92 | 4.66 | 4.66 |
321.41 | 3.57 | 3.57 |
311.37 | 3.16 | 3.16 |
324.34 | 2.21 | 2.21 |
370.25 | 3.63 | 3.63 |
601.41 | 4.34 | 4.34 |
348.43 | 2.03 | 2.03 |
389.53 | 4.75 | 4.75 |
622.57 | 2.43 | 2.43 |
435.49 | 4.56 | 4.56 |
435.49 | 4.56 | 4.56 |
321.34 | 2.01 | 2.01 |
355.44 | 4.16 | 4.16 |
501.59 | 5.16 | 5.16 |
475.50 | 4.14 | 4.14 |
287.39 | 2.89 | 2.89 |
517.56 | 4.04 | 4.04 |
336.42 | 1.50 | 1.50 |
230.23 | 0.73 | 0.73 |
379.46 | 4.27 | 4.27 |
395.28 | 2.44 | 2.44 |
457.49 | 3.63 | 3.63 |
500.61 | 5.76 | 5.76 |
493.57 | 3.96 | 3.96 |