Basic Information
ID: ALA2114874
Type: Functional
Description: PubChem BioAssay. Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inverse agonists of the Steroidogenic Factor 1 Nuclear Receptor (SF1; NR5A1). (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114874
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.53 | 3.12 | 3.12 |
| 306.35 | 1.71 | 1.71 |
| 371.33 | 4.42 | 4.42 |
| 343.45 | 3.41 | 3.41 |
| 406.39 | 4.12 | 4.12 |
| 397.21 | 2.65 | 2.65 |
| 355.35 | 2.32 | 2.32 |
| 476.33 | 3.18 | 3.18 |
| 365.39 | 2.85 | 2.85 |
| 449.53 | 2.05 | 2.05 |
| 395.39 | 3.91 | 3.91 |
| 325.16 | 1.85 | 1.85 |
| 425.18 | 3.94 | 3.94 |
| 329.39 | 2.41 | 2.41 |
| 390.74 | 3.28 | 3.28 |
| 336.35 | 2.68 | 2.68 |
| 371.48 | 3.11 | 3.11 |
| 362.45 | 2.18 | 2.18 |
| 517.61 | 2.54 | 2.54 |
| 322.71 | 2.58 | 2.58 |
| 374.47 | 2.87 | 2.87 |
| 454.93 | 2.17 | 2.17 |
| 382.46 | 2.38 | 2.38 |
| 315.36 | 2.04 | 2.04 |
| 391.43 | 1.37 | 1.37 |
| 381.37 | 1.46 | 1.46 |
| 400.52 | 3.47 | 3.47 |
| 386.43 | 3.29 | 3.29 |
| 328.37 | 3.31 | 3.31 |
| 369.38 | 2.76 | 2.76 |
| 348.84 | 4.74 | 4.74 |
| 311.13 | 1.54 | 1.54 |
| 349.41 | 2.93 | 2.93 |
| 398.45 | 2.20 | 2.20 |
| 398.35 | 1.58 | 1.58 |
| 337.38 | 3.02 | 3.02 |
| 430.35 | 3.59 | 3.59 |
| 455.54 | 3.16 | 3.16 |
| 307.29 | 1.22 | 1.22 |
| 386.45 | 2.17 | 2.17 |
| 422.47 | 2.93 | 2.93 |
| 432.55 | 4.43 | 4.43 |
| 463.54 | 1.50 | 1.50 |
| 380.40 | 0.77 | 0.77 |
| 453.95 | 2.30 | 2.30 |
| 329.39 | 2.41 | 2.41 |
| 388.46 | 1.88 | 1.88 |
| 349.43 | 3.30 | 3.30 |
| 460.51 | 1.49 | 1.49 |
| 350.37 | 4.04 | 4.04 |
| 348.84 | 0.32 | 0.32 |
| 391.41 | 1.87 | 1.87 |
| 519.80 | 2.62 | 2.62 |
| 421.41 | 1.86 | 1.86 |
| 414.55 | 3.86 | 3.86 |
| 320.35 | 4.03 | 4.03 |
| 358.81 | 1.89 | 1.89 |
| 342.38 | 2.43 | 2.43 |
| 400.48 | 1.89 | 1.89 |
| 372.48 | 3.18 | 3.18 |
| 401.42 | 2.81 | 2.81 |
| 319.40 | 3.54 | 3.54 |
| 306.24 | 3.04 | 3.04 |
| 303.38 | 3.09 | 3.09 |
| 316.43 | 4.21 | 4.21 |
| 387.87 | 2.89 | 2.89 |
| 413.32 | 3.12 | 3.12 |
| 379.45 | 3.96 | 3.96 |
| 330.37 | 2.88 | 2.88 |
| 332.34 | 0.54 | 0.54 |
| 345.38 | 2.19 | 2.19 |
| 301.20 | 4.00 | 4.00 |
| 421.49 | 2.09 | 2.09 |
| 345.36 | 2.91 | 2.91 |
| 436.33 | 4.19 | 4.19 |
| 389.43 | 3.76 | 3.76 |
| 402.42 | 1.37 | 1.37 |
| 474.42 | 0.19 | 0.19 |
| 404.84 | 2.24 | 2.24 |
| 322.38 | 2.52 | 2.52 |
| 432.55 | 4.49 | 4.49 |
| 323.80 | 3.06 | 3.06 |
| 444.52 | 4.02 | 4.02 |
| 388.49 | 3.11 | 3.11 |
| 323.72 | 3.70 | 3.70 |
| 410.52 | 2.35 | 2.35 |
| 408.73 | 3.42 | 3.42 |
| 444.44 | 2.64 | 2.64 |
| 352.39 | 3.47 | 3.47 |
| 399.44 | 3.36 | 3.36 |
| 356.29 | 2.63 | 2.63 |
| 321.36 | 2.07 | 2.07 |
| 361.42 | 2.56 | 2.56 |
| 317.35 | 1.50 | 1.50 |
| 375.85 | 3.40 | 3.40 |
| 317.33 | 3.67 | 3.67 |
| 384.43 | 1.23 | 1.23 |
| 351.32 | 0.75 | 0.75 |
| 339.38 | 3.31 | 3.31 |
| 350.37 | 2.37 | 2.37 |
| 438.89 | 2.87 | 2.87 |
| 336.37 | 1.23 | 1.23 |
| 420.44 | 1.50 | 1.50 |
| 434.52 | 3.96 | 3.96 |
| 393.45 | 1.43 | 1.43 |
| 365.39 | 1.83 | 1.83 |
| 442.49 | 1.67 | 1.67 |
| 368.42 | 3.43 | 3.43 |
| 384.39 | 2.62 | 2.62 |
| 382.63 | 2.48 | 2.48 |
| 419.30 | 3.84 | 3.84 |
| 311.30 | 1.56 | 1.56 |
| 415.49 | 2.48 | 2.48 |
| 451.52 | 2.54 | 2.54 |
| 447.51 | 3.02 | 3.02 |
| 384.42 | 1.90 | 1.90 |
| 323.35 | 3.25 | 3.25 |
| 354.48 | 3.85 | 3.85 |
| 333.35 | 3.83 | 3.83 |
| 355.31 | 3.59 | 3.59 |
| 426.52 | 2.29 | 2.29 |
| 381.48 | 3.49 | 3.49 |
| 438.51 | 3.50 | 3.50 |
| 329.34 | 3.87 | 3.87 |
| 353.34 | 1.47 | 1.47 |
| 417.47 | 3.33 | 3.33 |
| 352.19 | 2.70 | 2.70 |
| 325.78 | 1.47 | 1.47 |
| 453.52 | 3.11 | 3.11 |
| 380.43 | 3.06 | 3.06 |
| 312.08 | 2.60 | 2.60 |
| 391.48 | 2.58 | 2.58 |
| 439.49 | 3.13 | 3.13 |
| 366.37 | 3.45 | 3.45 |
| 369.42 | 3.46 | 3.46 |
| 450.37 | 3.63 | 3.63 |
| 440.50 | 1.66 | 1.66 |
| 346.36 | 3.48 | 3.48 |
| 413.07 | 4.01 | 4.01 |
| 323.31 | 3.43 | 3.43 |
| 374.44 | 1.49 | 1.49 |
| 364.40 | 2.76 | 2.76 |
| 461.54 | 0.54 | 0.54 |
| 355.45 | 3.78 | 3.78 |
| 384.43 | 1.77 | 1.77 |
| 377.24 | 2.65 | 2.65 |
| 415.49 | 2.09 | 2.09 |
| 382.45 | 3.17 | 3.17 |
| 316.07 | 2.50 | 2.50 |
| 352.39 | 2.84 | 2.84 |
| 347.40 | 2.25 | 2.25 |
| 336.85 | 3.56 | 3.56 |
| 327.27 | 0.79 | 0.79 |
| 393.44 | 3.11 | 3.11 |
| 349.39 | 2.04 | 2.04 |
| 335.36 | 1.80 | 1.80 |
| 317.33 | 3.67 | 3.67 |
| 458.47 | 2.37 | 2.37 |
| 324.42 | 3.93 | 3.93 |
| 366.37 | 3.80 | 3.80 |
| 387.44 | 2.29 | 2.29 |
| 386.49 | 3.21 | 3.21 |
| 370.41 | 1.38 | 1.38 |
| 331.37 | 1.77 | 1.77 |
| 380.44 | -0.20 | -0.20 |
| 370.43 | 3.09 | 3.09 |
| 355.42 | 2.19 | 2.19 |
| 383.45 | 2.84 | 2.84 |
| 444.51 | 2.13 | 2.13 |
| 351.70 | 1.68 | 1.68 |
| 395.46 | 2.62 | 2.62 |
| 416.23 | 3.66 | 3.66 |
| 307.38 | 2.76 | 2.76 |
| 421.50 | 1.32 | 1.32 |
| 391.47 | 2.56 | 2.56 |
| 321.36 | 0.48 | 0.48 |
| 369.41 | 2.18 | 2.18 |
| 462.43 | 2.78 | 2.78 |
| 331.39 | 3.20 | 3.20 |
| 333.36 | 1.35 | 1.35 |
| 400.54 | 3.58 | 3.58 |
| 315.37 | 2.71 | 2.71 |
| 370.23 | 1.15 | 1.15 |
| 513.64 | 3.79 | 3.79 |
| 391.47 | 3.67 | 3.67 |
| 316.36 | 1.55 | 1.55 |
| 404.51 | 4.01 | 4.01 |
| 372.81 | 3.55 | 3.55 |
| 348.47 | 3.55 | 3.55 |
| 386.45 | 1.50 | 1.50 |
| 423.47 | 3.81 | 3.81 |
| 440.37 | 2.45 | 2.45 |
| 434.47 | 1.98 | 1.98 |
| 400.89 | 3.26 | 3.26 |
| 331.36 | 1.63 | 1.63 |
| 301.34 | 2.32 | 2.32 |
| 332.32 | 1.82 | 1.82 |
| 383.23 | 2.91 | 2.91 |
| 397.45 | 3.32 | 3.32 |
| 372.38 | 2.05 | 2.05 |
| 352.46 | 3.53 | 3.53 |
| 359.43 | 1.61 | 1.61 |
| 377.46 | 3.61 | 3.61 |
| 332.27 | 0.23 | 0.23 |
| 350.21 | 2.76 | 2.76 |
| 357.36 | 2.65 | 2.65 |
| 368.44 | 2.08 | 2.08 |
| 369.42 | 2.56 | 2.56 |
| 372.79 | 0.52 | 0.52 |
| 323.38 | 3.65 | 3.65 |
| 352.39 | 2.81 | 2.81 |
| 388.46 | 1.88 | 1.88 |
| 426.32 | 3.90 | 3.90 |
| 346.37 | 4.16 | 4.16 |
| 435.51 | 4.04 | 4.04 |
| 333.37 | 1.81 | 1.81 |
| 423.47 | 4.17 | 4.17 |
| 307.38 | 3.33 | 3.33 |
| 435.31 | 3.57 | 3.57 |
| 325.37 | 2.76 | 2.76 |
| 395.45 | 3.75 | 3.75 |
| 361.40 | 1.75 | 1.75 |
| 366.37 | 2.08 | 2.08 |
| 396.29 | 3.05 | 3.05 |
| 423.47 | 4.17 | 4.17 |
| 409.44 | 3.78 | 3.78 |
| 373.45 | 1.85 | 1.85 |
| 349.41 | 2.42 | 2.42 |
| 421.48 | 3.92 | 3.92 |
| 423.47 | 4.17 | 4.17 |
| 360.33 | 0.05 | 0.05 |
| 372.45 | 2.19 | 2.19 |
| 313.71 | 4.59 | 4.59 |
| 346.31 | -0.35 | -0.35 |
| 316.28 | -0.35 | -0.35 |
| 316.28 | -0.35 | -0.35 |
| 303.27 | 2.03 | 2.03 |
| 448.44 | 3.63 | 3.63 |
| 313.71 | 4.59 | 4.59 |