Basic Information
ID: ALA2114877
Type: Functional
Description: PubChem BioAssay. qHTS screen for small molecules that inhibit ELG1-dependent DNA repair: Hit Confirmation with MMS Viability. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114877
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.76 | 4.04 | 4.04 |
| 506.47 | 2.32 | 2.32 |
| 560.64 | 2.41 | 2.41 |
| 298.32 | -0.84 | -0.84 |
| 736.94 | 6.02 | 6.02 |
| 392.15 | -0.77 | -0.77 |
| 265.32 | 3.25 | 3.25 |
| 262.30 | 1.25 | 1.25 |
| 366.41 | 1.12 | 1.12 |
| 265.31 | 0.50 | 0.50 |
| 224.26 | 3.03 | 3.03 |
| 325.35 | -1.74 | -1.74 |
| 320.38 | 3.37 | 3.37 |
| 373.46 | 3.03 | 3.03 |
| 466.54 | 4.35 | 4.35 |
| 442.55 | 3.80 | 3.80 |
| 244.21 | -3.17 | -3.17 |
| 284.30 | -1.27 | -1.27 |
| 409.07 | ||
| 507.98 | -0.79 | -0.79 |
| 383.68 | 5.34 | 5.34 |
| 1111.34 | ||
| 266.23 | 2.07 | 2.07 |
| 431.53 | 2.58 | 2.58 |
| 420.44 | 3.75 | 3.75 |
| 344.81 | 3.39 | 3.39 |
| 482.63 | 4.16 | 4.16 |
| 528.02 | 3.42 | 3.42 |
| 259.31 | 3.44 | 3.44 |
| 361.42 | 4.60 | 4.60 |
| 356.82 | 3.12 | 3.12 |
| 290.39 | 2.49 | 2.49 |
| 387.32 | 3.96 | 3.96 |
| 534.61 | 3.09 | 3.09 |
| 431.90 | 3.47 | 3.47 |
| 426.47 | 3.07 | 3.07 |
| 332.45 | 4.12 | 4.12 |
| 466.58 | 4.49 | 4.49 |
| 478.55 | 2.57 | 2.57 |
| 467.62 | 4.66 | 4.66 |
| 309.20 | 4.24 | 4.24 |
| 480.57 | 2.62 | 2.62 |
| 271.35 | 3.31 | 3.31 |
| 460.54 | 2.49 | 2.49 |
| 334.40 | 3.53 | 3.53 |
| 511.99 | 4.13 | 4.13 |
| 490.98 | 5.26 | 5.26 |
| 728.78 | -1.51 | -1.51 |
| 465.57 | 1.79 | 1.79 |
| 461.54 | 4.57 | 4.57 |
| 320.36 | 2.70 | 2.70 |
| 484.57 | 3.51 | 3.51 |
| 418.41 | 1.04 | 1.04 |
| 320.39 | 4.10 | 4.10 |
| 460.52 | 3.10 | 3.10 |
| 429.52 | 3.17 | 3.17 |
| 519.58 | 4.06 | 4.06 |
| 266.14 | 3.21 | 3.21 |
| 344.48 | 3.92 | 3.92 |
| 533.58 | 4.35 | 4.35 |
| 437.55 | 1.38 | 1.38 |
| 494.57 | 6.24 | 6.24 |
| 510.59 | 3.52 | 3.52 |
| 333.39 | 2.60 | 2.60 |
| 491.50 | 4.34 | 4.34 |
| 432.54 | 3.37 | 3.37 |
| 418.50 | 1.97 | 1.97 |
| 426.44 | 5.62 | 5.62 |
| 520.54 | 2.39 | 2.39 |
| 380.40 | 3.02 | 3.02 |
| 290.75 | 3.37 | 3.37 |
| 545.67 | 4.42 | 4.42 |
| 443.96 | 4.86 | 4.86 |
| 534.69 | 3.11 | 3.11 |
| 296.20 | -0.80 | -0.80 |
| 308.26 | -1.04 | -1.04 |
| 411.51 | 3.27 | 3.27 |
| 550.65 | 0.75 | 0.75 |
| 494.57 | 3.34 | 3.34 |
| 519.40 | 3.75 | 3.75 |
| 513.57 | 3.33 | 3.33 |
| 489.92 | 4.98 | 4.98 |
| 443.57 | 3.34 | 3.34 |
| 237.26 | 1.35 | 1.35 |
| 485.57 | 4.89 | 4.89 |
| 791.08 | 5.88 | 5.88 |
| 366.46 | 3.14 | 3.14 |
| 412.91 | 4.43 | 4.43 |
| 302.19 | 3.36 | 3.36 |
| 279.34 | 3.29 | 3.29 |
| 407.43 | 3.61 | 3.61 |
| 390.42 | 1.20 | 1.20 |
| 454.50 | 3.72 | 3.72 |
| 430.51 | 4.00 | 4.00 |
| 378.48 | 4.27 | 4.27 |
| 475.55 | 3.08 | 3.08 |
| 454.87 | 4.06 | 4.06 |
| 414.53 | 4.63 | 4.63 |
| 400.82 | 3.44 | 3.44 |
| 382.39 | 4.59 | 4.59 |
| 377.43 | 3.19 | 3.19 |
| 458.56 | 3.64 | 3.64 |
| 360.48 | 3.68 | 3.68 |
| 379.46 | 4.64 | 4.64 |
| 428.60 | 2.62 | 2.62 |
| 452.58 | 3.76 | 3.76 |
| 365.37 | 2.03 | 2.03 |
| 319.29 | 4.14 | 4.14 |
| 363.33 | 2.77 | 2.77 |
| 264.33 | 2.72 | 2.72 |
| 441.55 | 3.87 | 3.87 |
| 542.46 | 5.72 | 5.72 |
| 494.59 | 3.26 | 3.26 |
| 270.36 | 3.05 | 3.05 |
| 543.67 | 2.96 | 2.96 |
| 501.54 | 4.39 | 4.39 |
| 401.43 | 1.51 | 1.51 |
| 315.40 | 3.36 | 3.36 |
| 332.36 | 3.33 | 3.33 |
| 468.61 | 4.24 | 4.24 |
| 494.57 | 3.00 | 3.00 |
| 399.44 | 3.02 | 3.02 |
| 399.45 | 3.63 | 3.63 |
| 428.44 | 4.03 | 4.03 |
| 356.35 | 2.95 | 2.95 |
| 296.30 | 3.23 | 3.23 |
| 440.53 | 5.01 | 5.01 |
| 396.44 | 3.78 | 3.78 |
| 338.46 | 4.02 | 4.02 |
| 404.50 | 1.90 | 1.90 |
| 460.53 | 4.18 | 4.18 |
| 458.02 | 2.80 | 2.80 |
| 539.61 | 3.01 | 3.01 |
| 483.57 | 3.28 | 3.28 |
| 406.49 | 3.02 | 3.02 |
| 434.49 | 2.79 | 2.79 |
| 382.42 | 5.02 | 5.02 |
| 341.42 | 1.61 | 1.61 |
| 478.55 | 2.39 | 2.39 |
| 306.37 | 3.65 | 3.65 |
| 312.78 | 2.22 | 2.22 |
| 548.67 | 2.29 | 2.29 |
| 387.87 | 2.23 | 2.23 |
| 364.38 | 2.16 | 2.16 |
| 474.51 | 5.20 | 5.20 |
| 379.41 | 4.74 | 4.74 |
| 346.41 | 2.40 | 2.40 |
| 431.49 | 3.45 | 3.45 |
| 276.34 | 3.72 | 3.72 |
| 389.46 | 2.16 | 2.16 |
| 353.38 | 2.91 | 2.91 |
| 547.69 | 4.79 | 4.79 |
| 371.26 | 2.64 | 2.64 |
| 323.61 | 5.43 | 5.43 |
| 339.27 | 3.59 | 3.59 |
| 340.38 | 3.87 | 3.87 |
| 446.59 | 3.79 | 3.79 |
| 337.38 | 3.47 | 3.47 |
| 353.39 | 3.02 | 3.02 |
| 310.83 | 3.11 | 3.11 |
| 335.27 | 4.87 | 4.87 |
| 459.54 | 2.21 | 2.21 |
| 424.55 | 2.76 | 2.76 |
| 392.45 | 2.88 | 2.88 |
| 362.41 | 2.12 | 2.12 |
| 474.51 | 3.66 | 3.66 |
| 410.43 | 2.72 | 2.72 |
| 408.45 | 4.51 | 4.51 |
| 464.47 | 1.99 | 1.99 |
| 489.65 | 4.64 | 4.64 |
| 399.49 | 4.02 | 4.02 |
| 383.40 | 5.02 | 5.02 |
| 420.42 | 4.55 | 4.55 |
| 384.53 | 3.32 | 3.32 |
| 410.27 | 4.03 | 4.03 |
| 387.48 | 3.95 | 3.95 |
| 447.72 | 5.07 | 5.07 |
| 1009.18 | ||
| 267.28 | 3.55 | 3.55 |
| 374.39 | 1.80 | 1.80 |
| 408.41 | 3.06 | 3.06 |
| 367.86 | 2.77 | 2.77 |
| 431.53 | 2.12 | 2.12 |
| 333.39 | 4.39 | 4.39 |
| 359.30 | 4.40 | 4.40 |
| 333.36 | 3.99 | 3.99 |
| 382.90 | 3.92 | 3.92 |
| 410.42 | 3.71 | 3.71 |
| 428.54 | 3.63 | 3.63 |
| 326.81 | 2.61 | 2.61 |
| 459.45 | 5.56 | 5.56 |
| 495.01 | 4.64 | 4.64 |
| 352.51 | 4.38 | 4.38 |
| 417.47 | 3.18 | 3.18 |
| 305.34 | 2.54 | 2.54 |
| 474.59 | 3.72 | 3.72 |
| 445.46 | 7.16 | 7.16 |
| 410.43 | 3.06 | 3.06 |
| 342.36 | 1.73 | 1.73 |
| 512.63 | 5.53 | 5.53 |
| 429.55 | 4.18 | 4.18 |
| 375.43 | 3.18 | 3.18 |
| 402.46 | 4.35 | 4.35 |
| 423.49 | 4.16 | 4.16 |
| 405.44 | 4.03 | 4.03 |
| 295.34 | 3.86 | 3.86 |
| 426.32 | 2.82 | 2.82 |
| 257.29 | 2.19 | 2.19 |
| 443.55 | 4.03 | 4.03 |
| 566.65 | 4.16 | 4.16 |
| 368.43 | 3.35 | 3.35 |
| 429.86 | 2.59 | 2.59 |
| 396.40 | 4.75 | 4.75 |
| 455.50 | 4.24 | 4.24 |
| 544.61 | 2.92 | 2.92 |
| 432.57 | 3.72 | 3.72 |
| 485.59 | 4.01 | 4.01 |
| 407.52 | 2.35 | 2.35 |
| 473.62 | 4.17 | 4.17 |
| 447.63 | 4.60 | 4.60 |
| 406.51 | 1.50 | 1.50 |
| 404.40 | 4.16 | 4.16 |
| 453.50 | 1.63 | 1.63 |
| 397.43 | 1.93 | 1.93 |
| 467.60 | 3.44 | 3.44 |
| 336.35 | 1.92 | 1.92 |
| 514.61 | 4.11 | 4.11 |
| 362.41 | 2.62 | 2.62 |
| 476.58 | 2.35 | 2.35 |
| 488.65 | 4.19 | 4.19 |
| 475.50 | 4.53 | 4.53 |
| 606.84 | 5.37 | 5.37 |
| 450.54 | 3.43 | 3.43 |
| 386.41 | 4.02 | 4.02 |
| 451.48 | 5.10 | 5.10 |
| 431.49 | 5.39 | 5.39 |
| 431.49 | 3.31 | 3.31 |
| 424.43 | 3.90 | 3.90 |
| 397.31 | 3.14 | 3.14 |
| 326.79 | 3.79 | 3.79 |
| 437.74 | 4.85 | 4.85 |
| 356.42 | 2.64 | 2.64 |
| 442.59 | 2.43 | 2.43 |
| 455.55 | 2.40 | 2.40 |
| 492.60 | 4.15 | 4.15 |
| 415.90 | 4.21 | 4.21 |
| 329.40 | 3.13 | 3.13 |
| 462.93 | 5.49 | 5.49 |
| 578.78 | 4.76 | 4.76 |
| 309.44 | 4.15 | 4.15 |
| 402.50 | 4.39 | 4.39 |
| 342.40 | 3.84 | 3.84 |
| 312.31 | 3.48 | 3.48 |
| 398.51 | 4.56 | 4.56 |
| 480.63 | 3.98 | 3.98 |
| 447.37 | 3.98 | 3.98 |
| 531.61 | 5.15 | 5.15 |
| 416.54 | 3.89 | 3.89 |
| 548.67 | 2.43 | 2.43 |
| 410.42 | 3.71 | 3.71 |
| 324.43 | 1.96 | 1.96 |
| 303.79 | 3.91 | 3.91 |
| 331.46 | 1.49 | 1.49 |
| 574.63 | 2.52 | 2.52 |
| 391.54 | 3.22 | 3.22 |
| 399.52 | 3.09 | 3.09 |
| 392.88 | 3.74 | 3.74 |
| 412.54 | 3.55 | 3.55 |
| 238.29 | 2.82 | 2.82 |
| 386.46 | 4.36 | 4.36 |
| 492.04 | 2.93 | 2.93 |
| 378.90 | 4.01 | 4.01 |
| 487.65 | 3.25 | 3.25 |
| 440.55 | 3.16 | 3.16 |
| 417.48 | 2.78 | 2.78 |
| 472.54 | 4.32 | 4.32 |
| 586.68 | -1.44 | -1.44 |
| 412.48 | 3.69 | 3.69 |
| 368.41 | 2.72 | 2.72 |
| 253.26 | 2.20 | 2.20 |
| 495.62 | 3.43 | 3.43 |
| 467.57 | 2.81 | 2.81 |
| 323.35 | 3.04 | 3.04 |
| 304.37 | 2.75 | 2.75 |
| 495.54 | 4.48 | 4.48 |
| 452.56 | 2.35 | 2.35 |
| 497.58 | 5.89 | 5.89 |
| 540.01 | 5.29 | 5.29 |
| 248.71 | 3.03 | 3.03 |
| 384.38 | 3.22 | 3.22 |
| 272.26 | 3.15 | 3.15 |
| 439.56 | 2.37 | 2.37 |
| 432.55 | 4.24 | 4.24 |
| 570.55 | 3.05 | 3.05 |
| 497.00 | 4.09 | 4.09 |
| 384.36 | 2.93 | 2.93 |
| 407.34 | 3.40 | 3.40 |
| 462.44 | 4.97 | 4.97 |
| 427.55 | 3.70 | 3.70 |
| 359.40 | 3.75 | 3.75 |
| 382.29 | 3.80 | 3.80 |
| 292.72 | 3.10 | 3.10 |
| 744.81 | 3.85 | 3.85 |
| 370.45 | 2.54 | 2.54 |
| 572.68 | 4.76 | 4.76 |
| 578.71 | 4.11 | 4.11 |
| 647.69 | 3.54 | 3.54 |
| 525.68 | 4.42 | 4.42 |
| 423.92 | 2.03 | 2.03 |
| 366.37 | 2.53 | 2.53 |
| 772.86 | 4.63 | 4.63 |
| 614.79 | 4.78 | 4.78 |
| 480.52 | 4.84 | 4.84 |
| 388.52 | 2.82 | 2.82 |
| 486.49 | 1.80 | 1.80 |
| 454.96 | 4.07 | 4.07 |
| 396.45 | 1.27 | 1.27 |
| 667.71 | 5.63 | 5.63 |
| 630.62 | 2.15 | 2.15 |
| 583.44 | 3.88 | 3.88 |
| 369.47 | 4.08 | 4.08 |
| 448.57 | 4.42 | 4.42 |
| 422.40 | 3.63 | 3.63 |
| 542.60 | 3.19 | 3.19 |
| 347.40 | 1.17 | 1.17 |
| 526.97 | 4.31 | 4.31 |
| 510.63 | 2.53 | 2.53 |
| 390.42 | 2.42 | 2.42 |
| 487.56 | 2.31 | 2.31 |
| 396.49 | 3.94 | 3.94 |
| 439.59 | 2.40 | 2.40 |
| 475.54 | 6.73 | 6.73 |
| 445.54 | 1.32 | 1.32 |
| 425.58 | 2.32 | 2.32 |
| 653.53 | 7.01 | 7.01 |
| 454.50 | 3.05 | 3.05 |
| 548.64 | 5.93 | 5.93 |
| 348.36 | 1.79 | 1.79 |
| 466.54 | 3.30 | 3.30 |
| 367.41 | 4.09 | 4.09 |
| 572.68 | 4.76 | 4.76 |
| 463.29 | 1.40 | 1.40 |
| 473.25 | 3.10 | 3.10 |
| 800.92 | 5.41 | 5.41 |
| 455.51 | 3.66 | 3.66 |
| 446.51 | 4.96 | 4.96 |
| 402.95 | 5.36 | 5.36 |
| 586.70 | 5.15 | 5.15 |
| 758.84 | 4.24 | 4.24 |
| 524.66 | 3.26 | 3.26 |
| 370.43 | 3.66 | 3.66 |
| 474.11 | 3.81 | 3.81 |
| 398.53 | 4.63 | 4.63 |
| 459.63 | 3.57 | 3.57 |
| 503.15 | 4.59 | 4.59 |
| 366.43 | 3.14 | 3.14 |
| 379.21 | 2.94 | 2.94 |
| 401.50 | 2.96 | 2.96 |
| 357.40 | 2.86 | 2.86 |
| 389.46 | 3.64 | 3.64 |
| 780.95 | 2.22 | 2.22 |
| 444.52 | 2.83 | 2.83 |
| 411.87 | 5.37 | 5.37 |
| 485.53 | 4.20 | 4.20 |
| 529.56 | 4.11 | 4.11 |
| 447.37 | 2.31 | 2.31 |
| 350.33 | 1.68 | 1.68 |
| 569.71 | 3.03 | 3.03 |
| 324.34 | 2.21 | 2.21 |
| 370.25 | 3.63 | 3.63 |
| 601.41 | 4.34 | 4.34 |
| 389.53 | 4.75 | 4.75 |
| 622.57 | 2.43 | 2.43 |
| 435.49 | 4.56 | 4.56 |
| 435.49 | 4.56 | 4.56 |
| 321.34 | 2.01 | 2.01 |
| 355.44 | 4.16 | 4.16 |
| 334.44 | 2.97 | 2.97 |
| 475.50 | 4.14 | 4.14 |
| 517.56 | 4.04 | 4.04 |
| 230.23 | 0.73 | 0.73 |
| 379.46 | 4.27 | 4.27 |
| 395.28 | 2.44 | 2.44 |