Basic Information
ID: ALA2114882
Type: Functional
Description: PubChem BioAssay. Thermal shift assay to identify compound binding to Kelch domain of Keap1 protein Measured in Biochemical System Using RT-PCR - 2119-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114882
Max_Activity_Concent
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.22 | 2.12 | 2.12 |
| 406.62 | 3.98 | 3.98 |
| 238.33 | 3.07 | 3.07 |
| 222.63 | 1.52 | 1.52 |
| 240.21 | 1.87 | 1.87 |
| 504.64 | -0.02 | -0.02 |
| 217.27 | 4.07 | 4.07 |
| 214.22 | 2.33 | 2.33 |
| 362.23 | 4.06 | 4.06 |
| 399.45 | 3.39 | 3.39 |
| 341.43 | 3.30 | 3.30 |
| 337.42 | 3.15 | 3.15 |
| 309.37 | 2.51 | 2.51 |
| 457.91 | 1.85 | 1.85 |
| 579.99 | 0.00 | 0.00 |
| 343.39 | 3.97 | 3.97 |
| 345.20 | 4.76 | 4.76 |
| 223.25 | 1.67 | 1.67 |
| 339.35 | 3.05 | 3.05 |
| 316.74 | 2.68 | 2.68 |
| 362.39 | 3.20 | 3.20 |
| 274.36 | 3.69 | 3.69 |
| 325.37 | 2.03 | 2.03 |
| 318.76 | 1.71 | 1.71 |
| 374.27 | 4.42 | 4.42 |
| 298.35 | 4.66 | 4.66 |
| 233.29 | 2.57 | 2.57 |
| 368.39 | 1.89 | 1.89 |
| 499.35 | 4.44 | 4.44 |
| 418.45 | 2.91 | 2.91 |
| 476.53 | 4.00 | 4.00 |
| 563.99 | 1.03 | 1.03 |
| 279.73 | 2.22 | 2.22 |
| 319.36 | 3.41 | 3.41 |
| 322.46 | 3.31 | 3.31 |
| 255.25 | 4.43 | 4.43 |
| 295.35 | 2.41 | 2.41 |
| 423.49 | 5.52 | 5.52 |
| 311.39 | 2.36 | 2.36 |
| 218.21 | 1.33 | 1.33 |
| 365.43 | 3.73 | 3.73 |
| 336.35 | 2.81 | 2.81 |
| 458.57 | 4.23 | 4.23 |
| 298.37 | 3.12 | 3.12 |
| 299.38 | 1.80 | 1.80 |
| 536.54 | 2.70 | 2.70 |
| 321.41 | 2.10 | 2.10 |
| 400.49 | 2.16 | 2.16 |
| 241.29 | 2.49 | 2.49 |
| 251.67 | 2.86 | 2.86 |
| 268.32 | 2.66 | 2.66 |
| 316.37 | 1.44 | 1.44 |
| 311.34 | 1.59 | 1.59 |
| 166.18 | 0.86 | 0.86 |
| 311.35 | 1.72 | 1.72 |
| 402.40 | 1.97 | 1.97 |
| 348.26 | 3.38 | 3.38 |
| 408.46 | 2.14 | 2.14 |
| 275.35 | 3.56 | 3.56 |
| 281.31 | 2.82 | 2.82 |
| 496.39 | 2.87 | 2.87 |
| 331.37 | 1.47 | 1.47 |
| 320.35 | 2.85 | 2.85 |
| 352.42 | 1.72 | 1.72 |
| 232.24 | 0.93 | 0.93 |
| 357.46 | 3.13 | 3.13 |
| 360.41 | 3.38 | 3.38 |
| 286.28 | 1.61 | 1.61 |
| 262.29 | 1.08 | 1.08 |
| 169.27 | 2.19 | 2.19 |
| 361.38 | 1.89 | 1.89 |
| 474.52 | 2.69 | 2.69 |
| 323.74 | 4.00 | 4.00 |
| 280.27 | 2.69 | 2.69 |
| 180.12 | 0.71 | 0.71 |
| 488.57 | 2.75 | 2.75 |
| 439.50 | 4.36 | 4.36 |
| 366.37 | 3.11 | 3.11 |
| 249.32 | 3.27 | 3.27 |
| 224.29 | 1.61 | 1.61 |
| 309.41 | 4.57 | 4.57 |
| 385.38 | 3.07 | 3.07 |
| 474.41 | 5.39 | 5.39 |
| 411.51 | 4.51 | 4.51 |
| 393.24 | 3.22 | 3.22 |
| 347.33 | 4.07 | 4.07 |
| 240.26 | 2.11 | 2.11 |
| 315.40 | 3.36 | 3.36 |
| 361.17 | 3.83 | 3.83 |
| 341.42 | 3.11 | 3.11 |
| 426.49 | 4.30 | 4.30 |
| 404.47 | 4.37 | 4.37 |
| 326.32 | -0.22 | -0.22 |
| 417.96 | 5.56 | 5.56 |
| 311.33 | 2.64 | 2.64 |
| 441.50 | 4.67 | 4.67 |
| 444.48 | 2.31 | 2.31 |
| 373.84 | 3.52 | 3.52 |
| 240.26 | 2.04 | 2.04 |
| 410.74 | 4.54 | 4.54 |
| 448.88 | 4.04 | 4.04 |
| 360.41 | 3.38 | 3.38 |
| 280.24 | 0.00 | 0.00 |
| 217.25 | 2.66 | 2.66 |
| 437.30 | 3.30 | 3.30 |
| 349.39 | 3.70 | 3.70 |
| 350.36 | 1.81 | 1.81 |
| 366.42 | 3.19 | 3.19 |
| 454.47 | 2.64 | 2.64 |
| 306.32 | 2.46 | 2.46 |
| 377.88 | 5.04 | 5.04 |
| 420.44 | 1.23 | 1.23 |
| 302.42 | 2.50 | 2.50 |
| 454.93 | 4.09 | 4.09 |
| 304.76 | 3.10 | 3.10 |
| 327.38 | 2.61 | 2.61 |
| 226.24 | 1.65 | 1.65 |
| 265.27 | 3.44 | 3.44 |
| 288.31 | 3.22 | 3.22 |
| 365.42 | 2.16 | 2.16 |
| 334.38 | 3.09 | 3.09 |
| 454.12 | 5.53 | 5.53 |
| 392.48 | 2.93 | 2.93 |
| 260.30 | 3.18 | 3.18 |
| 288.39 | 4.15 | 4.15 |
| 256.27 | 3.73 | 3.73 |
| 341.86 | 2.36 | 2.36 |
| 340.40 | 4.09 | 4.09 |
| 427.51 | 3.16 | 3.16 |
| 427.57 | 2.29 | 2.29 |
| 256.26 | 2.13 | 2.13 |
| 285.31 | 1.69 | 1.69 |
| 445.44 | 5.88 | 5.88 |
| 407.81 | 3.93 | 3.93 |
| 261.35 | 3.13 | 3.13 |
| 402.43 | 4.67 | 4.67 |
| 332.74 | 3.09 | 3.09 |
| 245.27 | 1.15 | 1.15 |
| 225.29 | 2.71 | 2.71 |
| 267.28 | 3.08 | 3.08 |
| 310.69 | 2.49 | 2.49 |
| 309.29 | 3.51 | 3.51 |
| 399.49 | 4.04 | 4.04 |
| 312.37 | 3.01 | 3.01 |
| 387.36 | 1.68 | 1.68 |
| 345.41 | 4.18 | 4.18 |
| 331.38 | 3.58 | 3.58 |
| 413.48 | 2.85 | 2.85 |
| 334.42 | 2.91 | 2.91 |
| 232.29 | 1.93 | 1.93 |
| 395.42 | 3.30 | 3.30 |
| 298.73 | 3.58 | 3.58 |
| 369.88 | 3.15 | 3.15 |
| 283.29 | 1.41 | 1.41 |
| 408.42 | 4.65 | 4.65 |
| 320.37 | 3.83 | 3.83 |
| 277.35 | 2.80 | 2.80 |
| 314.39 | 2.44 | 2.44 |
| 410.45 | 4.23 | 4.23 |
| 357.46 | 2.90 | 2.90 |
| 310.31 | 1.24 | 1.24 |
| 418.48 | 1.15 | 1.15 |
| 351.41 | 1.63 | 1.63 |
| 276.21 | 2.35 | 2.35 |
| 350.16 | 2.49 | 2.49 |
| 411.56 | 3.37 | 3.37 |
| 276.32 | 1.34 | 1.34 |
| 258.30 | 2.90 | 2.90 |
| 382.89 | 2.95 | 2.95 |
| 446.50 | 3.30 | 3.30 |
| 383.50 | 2.69 | 2.69 |
| 363.80 | 4.70 | 4.70 |
| 593.70 | 3.94 | 3.94 |
| 301.30 | 2.30 | 2.30 |
| 309.42 | 2.45 | 2.45 |
| 368.48 | 4.86 | 4.86 |
| 355.45 | 1.66 | 1.66 |
| 254.72 | 2.24 | 2.24 |
| 318.76 | 2.95 | 2.95 |
| 265.07 | 1.75 | 1.75 |
| 420.46 | 4.01 | 4.01 |
| 401.24 | 1.41 | 1.41 |
| 345.36 | 2.84 | 2.84 |
| 355.32 | 2.51 | 2.51 |
| 378.39 | 2.18 | 2.18 |
| 327.41 | 3.96 | 3.96 |
| 279.72 | 2.17 | 2.17 |
| 220.24 | 2.66 | 2.66 |
| 282.81 | 2.81 | 2.81 |
| 248.35 | 2.72 | 2.72 |
| 280.72 | 1.40 | 1.40 |
| 339.30 | 1.67 | 1.67 |
| 242.41 | 2.36 | 2.36 |
| 341.44 | 3.12 | 3.12 |
| 526.53 | 4.11 | 4.11 |
| 458.57 | 3.14 | 3.14 |
| 274.33 | 3.67 | 3.67 |
| 330.48 | 2.22 | 2.22 |
| 290.32 | 3.64 | 3.64 |
| 355.51 | 3.52 | 3.52 |
| 322.32 | 2.57 | 2.57 |
| 321.41 | 2.10 | 2.10 |
| 237.69 | 1.30 | 1.30 |
| 287.17 | 3.81 | 3.81 |
| 379.38 | 4.69 | 4.69 |
| 303.32 | 2.80 | 2.80 |
| 298.35 | 2.62 | 2.62 |
| 524.64 | 5.43 | 5.43 |
| 427.48 | 5.72 | 5.72 |
| 285.31 | 1.02 | 1.02 |
| 382.37 | 2.24 | 2.24 |
| 234.69 | 2.32 | 2.32 |
| 320.35 | 3.72 | 3.72 |
| 431.44 | 5.55 | 5.55 |
| 334.40 | 2.00 | 2.00 |
| 355.19 | 3.81 | 3.81 |
| 289.77 | 2.76 | 2.76 |
| 262.28 | 2.42 | 2.42 |
| 294.31 | 2.94 | 2.94 |
| 346.38 | 2.02 | 2.02 |
| 403.46 | 1.89 | 1.89 |
| 311.37 | 2.80 | 2.80 |
| 319.58 | 2.44 | 2.44 |
| 447.65 | 4.12 | 4.12 |
| 317.44 | 5.22 | 5.22 |
| 312.76 | 3.52 | 3.52 |
| 263.41 | 3.04 | 3.04 |
| 377.40 | 3.92 | 3.92 |
| 264.26 | 1.82 | 1.82 |
| 480.52 | 2.70 | 2.70 |
| 294.29 | 1.56 | 1.56 |
| 355.30 | 2.38 | 2.38 |
| 565.65 | 3.16 | 3.16 |
| 302.33 | 3.53 | 3.53 |
| 453.52 | 3.69 | 3.69 |
| 282.28 | 3.07 | 3.07 |
| 251.24 | 3.05 | 3.05 |
| 326.72 | 2.18 | 2.18 |
| 382.46 | 3.20 | 3.20 |
| 321.81 | 1.77 | 1.77 |
| 237.26 | 4.29 | 4.29 |
| 284.32 | 2.23 | 2.23 |
| 364.52 | 4.39 | 4.39 |
| 399.44 | 0.71 | 0.71 |
| 310.42 | 5.20 | 5.20 |
| 289.34 | 0.75 | 0.75 |
| 292.42 | 4.81 | 4.81 |
| 348.41 | 3.63 | 3.63 |
| 411.57 | 3.05 | 3.05 |
| 445.99 | 2.15 | 2.15 |
| 391.88 | 4.13 | 4.13 |
| 319.70 | 2.81 | 2.81 |
| 327.39 | 2.10 | 2.10 |
| 293.28 | 2.93 | 2.93 |
| 312.37 | 3.01 | 3.01 |
| 383.50 | 2.64 | 2.64 |
| 362.51 | 2.83 | 2.83 |
| 229.28 | 1.93 | 1.93 |
| 336.35 | 2.03 | 2.03 |
| 336.39 | 3.88 | 3.88 |
| 487.58 | 5.05 | 5.05 |
| 288.39 | 1.71 | 1.71 |
| 319.32 | 3.05 | 3.05 |
| 313.31 | 4.83 | 4.83 |
| 457.52 | 2.71 | 2.71 |
| 384.48 | 2.36 | 2.36 |
| 369.48 | 2.38 | 2.38 |
| 372.42 | 4.34 | 4.34 |
| 523.53 | 5.13 | 5.13 |
| 409.44 | 2.75 | 2.75 |
| 482.52 | 5.62 | 5.62 |
| 459.51 | 2.41 | 2.41 |
| 257.29 | 2.43 | 2.43 |
| 316.32 | 4.24 | 4.24 |
| 327.47 | 4.36 | 4.36 |
| 342.44 | 3.10 | 3.10 |
| 329.36 | 3.84 | 3.84 |
| 405.49 | 3.10 | 3.10 |
| 324.33 | 2.43 | 2.43 |
| 288.22 | -0.04 | -0.04 |
| 388.47 | 4.36 | 4.36 |
| 413.45 | 5.41 | 5.41 |
| 281.36 | 3.79 | 3.79 |
| 406.47 | 4.74 | 4.74 |
| 383.50 | 2.69 | 2.69 |
| 239.34 | 2.59 | 2.59 |
| 269.26 | 1.14 | 1.14 |
| 388.43 | 3.76 | 3.76 |
| 372.42 | 4.34 | 4.34 |
| 307.34 | 2.06 | 2.06 |
| 432.48 | 3.30 | 3.30 |
| 405.50 | 3.31 | 3.31 |
| 339.35 | 3.05 | 3.05 |
| 380.41 | 1.99 | 1.99 |
| 451.59 | 4.14 | 4.14 |
| 378.52 | 2.88 | 2.88 |
| 234.28 | 0.72 | 0.72 |
| 482.54 | 4.64 | 4.64 |
| 343.43 | 2.82 | 2.82 |
| 383.36 | 2.77 | 2.77 |
| 321.36 | 1.91 | 1.91 |
| 295.37 | 3.10 | 3.10 |
| 371.51 | 3.17 | 3.17 |
| 282.77 | 2.61 | 2.61 |
| 364.88 | 3.71 | 3.71 |
| 352.43 | 3.18 | 3.18 |
| 264.28 | 3.47 | 3.47 |
| 211.24 | 1.64 | 1.64 |
| 297.38 | 2.71 | 2.71 |
| 279.26 | 0.12 | 0.12 |
| 490.63 | 2.87 | 2.87 |
| 358.47 | 3.91 | 3.91 |
| 371.46 | 2.18 | 2.18 |
| 250.30 | 2.67 | 2.67 |
| 337.42 | 2.97 | 2.97 |
| 278.40 | 2.99 | 2.99 |
| 382.41 | 3.78 | 3.78 |
| 335.19 | 3.51 | 3.51 |
| 215.21 | 1.29 | 1.29 |
| 477.74 | 0.71 | 0.71 |
| 392.91 | 4.08 | 4.08 |
| 217.27 | 1.58 | 1.58 |
| 265.36 | 2.57 | 2.57 |
| 393.90 | 2.49 | 2.49 |
| 240.31 | 3.66 | 3.66 |
| 387.51 | 1.72 | 1.72 |
| 591.54 | 3.19 | 3.19 |
| 389.24 | 0.54 | 0.54 |
| 536.66 | 1.49 | 1.49 |
| 364.79 | 2.90 | 2.90 |
| 358.83 | 2.12 | 2.12 |
| 357.36 | 2.41 | 2.41 |
| 303.33 | 2.77 | 2.77 |
| 363.85 | 3.23 | 3.23 |
| 310.31 | 1.15 | 1.15 |
| 380.45 | 4.71 | 4.71 |
| 437.95 | 3.49 | 3.49 |
| 257.08 | 1.97 | 1.97 |
| 555.58 | 1.63 | 1.63 |
| 226.24 | 2.03 | 2.03 |
| 430.56 | 0.11 | 0.11 |
| 442.45 | 1.07 | 1.07 |
| 464.52 | 3.73 | 3.73 |
| 504.56 | 3.45 | 3.45 |
| 282.34 | 3.06 | 3.06 |
| 323.81 | 3.50 | 3.50 |
| 428.00 | 2.97 | 2.97 |
| 315.35 | 3.54 | 3.54 |
| 433.36 | 3.07 | 3.07 |
| 460.53 | 3.60 | 3.60 |
| 240.26 | 3.70 | 3.70 |
| 250.26 | 2.52 | 2.52 |
| 514.52 | 3.95 | 3.95 |
| 312.24 | 0.24 | 0.24 |
| 267.31 | 1.86 | 1.86 |
| 358.45 | 0.97 | 0.97 |
| 318.35 | 1.57 | 1.57 |
| 436.53 | 5.05 | 5.05 |
| 325.41 | 2.51 | 2.51 |
| 200.24 | 2.13 | 2.13 |
| 428.51 | 2.90 | 2.90 |
| 300.20 | 2.73 | 2.73 |
| 491.55 | 0.02 | 0.02 |
| 319.41 | -0.57 | -0.57 |
| 380.42 | 3.86 | 3.86 |
| 385.40 | 1.94 | 1.94 |
| 500.67 | 3.33 | 3.33 |
| 488.59 | 4.22 | 4.22 |
| 396.49 | 1.96 | 1.96 |
| 509.38 | 1.38 | 1.38 |
| 493.63 | 4.05 | 4.05 |
| 306.32 | 3.03 | 3.03 |
| 306.37 | 2.14 | 2.14 |
| 474.49 | 3.19 | 3.19 |
| 380.40 | 2.85 | 2.85 |
| 485.56 | 3.36 | 3.36 |
| 392.78 | 3.09 | 3.09 |
| 457.51 | 2.32 | 2.32 |
| 386.51 | 3.58 | 3.58 |
| 324.38 | 2.99 | 2.99 |
| 332.40 | 4.26 | 4.26 |
| 341.36 | 3.19 | 3.19 |
| 306.37 | 1.95 | 1.95 |
| 391.85 | 3.45 | 3.45 |
| 359.43 | 2.56 | 2.56 |
| 349.82 | 2.39 | 2.39 |
| 427.46 | 2.61 | 2.61 |
| 393.47 | 3.37 | 3.37 |
| 433.49 | 2.75 | 2.75 |
| 260.32 | 3.28 | 3.28 |
| 341.80 | 4.03 | 4.03 |
| 352.44 | 2.30 | 2.30 |
| 399.38 | 3.06 | 3.06 |
| 402.31 | 5.54 | 5.54 |
| 430.56 | 0.11 | 0.11 |
| 447.52 | 3.06 | 3.06 |
| 294.31 | 2.34 | 2.34 |
| 490.49 | 3.54 | 3.54 |
| 227.27 | 2.42 | 2.42 |
| 260.30 | 2.66 | 2.66 |