Basic Information
ID: ALA2114894
Type: Functional
Description: PubChem BioAssay. Counterscreen for discovery of small molecules that bind to the HIV-1-gp120 binding antibody, PG9: TR-FRET-based biochemical high throughput dose response assay to identify small molecules that bind to the control antibody, PGV04, which binds to a distinct site on the HIV envelope different from the PG9 binding site. (Class of assay: confirmatory)
Organism: Human immunodeficiency virus 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2114894
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.32 | 3.74 | 3.74 |
| 286.40 | 3.79 | 3.79 |
| 258.35 | 2.97 | 2.97 |
| 454.56 | 2.95 | 2.95 |
| 477.61 | 4.26 | 4.26 |
| 387.56 | 5.02 | 5.02 |
| 419.55 | 4.30 | 4.30 |
| 323.78 | 3.06 | 3.06 |
| 372.41 | 2.41 | 2.41 |
| 392.50 | 2.68 | 2.68 |
| 357.39 | 2.46 | 2.46 |
| 377.47 | 4.14 | 4.14 |
| 416.53 | 3.04 | 3.04 |
| 200.27 | 2.78 | 2.78 |
| 446.43 | 3.77 | 3.77 |
| 252.34 | 3.51 | 3.51 |
| 350.37 | 4.04 | 4.04 |
| 353.37 | 4.10 | 4.10 |
| 429.51 | 4.47 | 4.47 |
| 316.36 | 3.26 | 3.26 |
| 338.39 | 4.22 | 4.22 |
| 312.35 | 3.51 | 3.51 |
| 392.87 | 4.89 | 4.89 |
| 410.01 | 4.40 | 4.40 |
| 436.49 | 3.11 | 3.11 |
| 358.49 | 3.87 | 3.87 |
| 348.41 | 5.15 | 5.15 |
| 452.61 | 5.07 | 5.07 |
| 341.39 | 3.69 | 3.69 |
| 262.26 | 1.83 | 1.83 |
| 325.48 | 3.84 | 3.84 |
| 457.51 | 1.89 | 1.89 |
| 380.23 | 3.12 | 3.12 |
| 290.37 | 3.74 | 3.74 |
| 332.31 | 4.52 | 4.52 |
| 231.28 | 2.41 | 2.41 |
| 261.35 | 2.35 | 2.35 |
| 473.55 | 2.29 | 2.29 |
| 437.42 | 1.98 | 1.98 |
| 407.45 | 4.19 | 4.19 |
| 390.19 | 1.84 | 1.84 |
| 275.31 | 3.96 | 3.96 |
| 441.51 | 3.90 | 3.90 |
| 344.41 | 3.88 | 3.88 |
| 203.29 | 1.92 | 1.92 |
| 449.51 | 3.69 | 3.69 |
| 374.49 | 4.21 | 4.21 |
| 552.72 | 3.92 | 3.92 |
| 364.36 | 3.57 | 3.57 |
| 384.39 | 3.94 | 3.94 |
| 382.51 | 4.66 | 4.66 |
| 409.87 | 4.16 | 4.16 |
| 201.25 | 2.35 | 2.35 |
| 324.36 | 3.80 | 3.80 |
| 416.46 | 2.41 | 2.41 |
| 270.36 | 3.03 | 3.03 |
| 322.36 | 3.24 | 3.24 |
| 368.42 | 2.74 | 2.74 |
| 308.36 | 4.10 | 4.10 |
| 339.35 | 2.87 | 2.87 |
| 353.83 | 4.75 | 4.75 |
| 385.83 | 4.17 | 4.17 |
| 391.50 | 4.03 | 4.03 |
| 355.42 | 3.40 | 3.40 |
| 380.47 | 2.97 | 2.97 |
| 211.29 | 3.68 | 3.68 |
| 441.29 | 2.91 | 2.91 |
| 431.90 | 3.54 | 3.54 |
| 284.40 | 3.65 | 3.65 |
| 294.34 | 3.79 | 3.79 |
| 553.50 | 3.39 | 3.39 |
| 443.30 | 3.18 | 3.18 |
| 524.37 | 4.09 | 4.09 |
| 306.37 | 3.38 | 3.38 |
| 270.36 | 3.69 | 3.69 |
| 337.33 | 2.88 | 2.88 |
| 286.40 | 3.43 | 3.43 |
| 228.28 | 2.10 | 2.10 |
| 408.85 | 3.71 | 3.71 |
| 465.07 | 6.24 | 6.24 |
| 215.28 | 2.71 | 2.71 |
| 429.47 | 5.05 | 5.05 |
| 431.56 | 3.69 | 3.69 |
| 203.29 | 1.92 | 1.92 |
| 441.44 | 2.30 | 2.30 |
| 359.86 | 2.69 | 2.69 |
| 315.46 | 4.38 | 4.38 |
| 407.59 | 4.41 | 4.41 |
| 359.33 | 2.23 | 2.23 |
| 253.35 | 1.71 | 1.71 |
| 309.37 | 4.17 | 4.17 |
| 335.38 | 2.71 | 2.71 |
| 591.55 | 6.88 | 6.88 |
| 465.57 | 7.40 | 7.40 |
| 511.64 | 7.70 | 7.70 |