Basic Information
ID: ALA2114895
Type: Functional
Description: PubChem BioAssay. qHTS assay for small molecule activators of the p53 signaling pathway. (Class of assay: confirmatory)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2114895
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 441.55 | 4.37 | 4.37 |
| 391.56 | 6.86 | 6.86 |
| 333.45 | 3.93 | 3.93 |
| 270.24 | 2.58 | 2.58 |
| 248.72 | 2.52 | 2.52 |
| 394.42 | 3.70 | 3.70 |
| 108.10 | 0.25 | 0.25 |
| 387.52 | 5.70 | 5.70 |
| 387.52 | 5.70 | 5.70 |
| 440.42 | 0.24 | 0.24 |
| 406.91 | 6.61 | 6.61 |
| 304.22 | 3.38 | 3.38 |
| 348.49 | 6.29 | 6.29 |
| 308.38 | 3.79 | 3.79 |
| 360.88 | 7.27 | 7.27 |
| 236.27 | 3.39 | 3.39 |
| 268.36 | 3.05 | 3.05 |
| 301.34 | 3.60 | 3.60 |
| 354.49 | 6.50 | 6.50 |
| 136.24 | 3.31 | 3.31 |
| 253.27 | 0.83 | 0.83 |
| 766.96 | 3.09 | 3.09 |
| 502.77 | 7.28 | 7.28 |
| 358.43 | 1.77 | 1.77 |
| 275.20 | 3.15 | 3.15 |
| 320.43 | 5.17 | 5.17 |
| 247.14 | 2.37 | 2.37 |
| 368.39 | 3.37 | 3.37 |
| 150.22 | 2.91 | 2.91 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 563.65 | 6.00 | 6.00 |
| 394.32 | 4.13 | 4.13 |
| 505.46 | 4.18 | 4.18 |
| 454.45 | 0.27 | 0.27 |
| 372.81 | 4.41 | 4.41 |
| 147.09 | -0.68 | -0.68 |
| 180.21 | 2.78 | 2.78 |
| 471.50 | 6.34 | 6.34 |
| 268.36 | 5.55 | 5.55 |
| 270.24 | 1.89 | 1.89 |
| 289.55 | 5.14 | 5.14 |
| 305.21 | 1.93 | 1.93 |
| 380.91 | 4.48 | 4.48 |
| 201.22 | 2.56 | 2.56 |
| 518.56 | 6.38 | 6.38 |
| 407.99 | 4.46 | 4.46 |
| 351.45 | 4.99 | 4.99 |
| 191.19 | 1.74 | 1.74 |
| 266.34 | 4.66 | 4.66 |
| 384.65 | 7.62 | 7.62 |
| 284.44 | 5.72 | 5.72 |
| 231.29 | 2.95 | 2.95 |
| 193.25 | 3.58 | 3.58 |
| 268.28 | 0.79 | 0.79 |
| 290.32 | 2.57 | 2.57 |
| 256.35 | 5.76 | 5.76 |
| 227.05 | 2.75 | 2.75 |
| 510.06 | 6.08 | 6.08 |
| 437.15 | 4.28 | 4.28 |
| 154.60 | 2.11 | 2.11 |
| 198.13 | 1.52 | 1.52 |
| 170.21 | 3.06 | 3.06 |
| 152.15 | 1.18 | 1.18 |
| 231.89 | 4.01 | 4.01 |
| 136.15 | 1.69 | 1.69 |
| 137.14 | 1.90 | 1.90 |
| 91.07 | -0.74 | -0.74 |
| 386.45 | 5.28 | 5.28 |
| 350.42 | 5.46 | 5.46 |
| 531.44 | 4.21 | 4.21 |
| 252.73 | 2.45 | 2.45 |
| 90.12 | 1.27 | 1.27 |
| 206.33 | 3.83 | 3.83 |
| 153.14 | 0.76 | 0.76 |
| 247.25 | 4.49 | 4.49 |
| 220.98 | 2.68 | 2.68 |
| 464.07 | 5.08 | 5.08 |
| 217.31 | 3.69 | 3.69 |
| 543.87 | 6.47 | 6.47 |
| 245.88 | 2.52 | 2.52 |
| 215.34 | 2.93 | 2.93 |
| 320.05 | 5.93 | 5.93 |
| 345.65 | 5.21 | 5.21 |
| 307.29 | 2.23 | 2.23 |
| 313.35 | 3.10 | 3.10 |
| 548.63 | 3.48 | 3.48 |
| 461.56 | 5.86 | 5.86 |
| 448.09 | 6.07 | 6.07 |
| 130.08 | -0.80 | -0.80 |
| 327.12 | 3.86 | 3.86 |
| 364.94 | 5.24 | 5.24 |
| 370.49 | 5.60 | 5.60 |
| 564.69 | 7.29 | 7.29 |
| 300.59 | 2.91 | 2.91 |
| 308.33 | 3.61 | 3.61 |
| 136.11 | 0.06 | 0.06 |
| 376.58 | 5.51 | 5.51 |
| 244.21 | -3.17 | -3.17 |
| 249.68 | 0.65 | 0.65 |
| 277.27 | 1.15 | 1.15 |
| 286.11 | 3.42 | 3.42 |
| 207.02 | 2.48 | 2.48 |
| 1255.44 | ||
| 494.48 | 6.38 | 6.38 |
| 209.25 | 2.19 | 2.19 |
| 325.36 | -0.39 | -0.39 |
| 340.51 | 5.90 | 5.90 |
| 404.82 | ||
| 625.56 | 4.18 | 4.18 |
| 152.24 | 2.88 | 2.88 |
| 563.99 | 1.03 | 1.03 |
| 225.29 | 3.41 | 3.41 |
| 387.82 | 4.24 | 4.24 |
| 416.51 | ||
| 297.27 | -2.63 | -2.63 |
| 490.64 | 4.62 | 4.62 |
| 370.92 | 2.47 | 2.47 |
| 318.37 | 3.58 | 3.58 |
| 287.17 | 4.56 | 4.56 |
| 385.48 | ||
| 367.04 | ||
| 579.99 | 0.00 | 0.00 |
| 1229.32 | ||
| 285.69 | -0.30 | -0.30 |
| 596.12 | ||
| 244.21 | -3.01 | -3.01 |
| 284.14 | 3.28 | 3.28 |
| 265.91 | 4.04 | 4.04 |
| 376.67 | 4.60 | 4.60 |
| 320.05 | 5.93 | 5.93 |
| 436.75 | 6.57 | 6.57 |
| 342.23 | 3.65 | 3.65 |
| 373.91 | 2.50 | 2.50 |
| 184.24 | 3.01 | 3.01 |
| 780.95 | 2.22 | 2.22 |
| 403.82 | 2.57 | 2.57 |
| 315.59 | 5.29 | 5.29 |
| 303.85 | ||
| 325.51 | ||
| 161.13 | 2.29 | 2.29 |
| 527.41 | 7.18 | 7.18 |
| 203.67 | 0.65 | 0.65 |
| 317.71 | 0.61 | 0.61 |
| 332.48 | 4.40 | 4.40 |
| 205.64 | 0.08 | 0.08 |
| 340.29 | 4.19 | 4.19 |
| 192.52 | 1.40 | 1.40 |
| 444.70 | 5.80 | 5.80 |
| 598.09 | 6.56 | 6.56 |
| 178.14 | -0.25 | -0.25 |
| 350.30 | 3.73 | 3.73 |
| 138.17 | 1.06 | 1.06 |
| 311.41 | 3.49 | 3.49 |
| 212.42 | 6.10 | 6.10 |
| 100.12 | 0.55 | 0.55 |
| 248.71 | 2.97 | 2.97 |
| 462.12 | 6.38 | 6.38 |
| 259.18 | 2.21 | 2.21 |
| 144.39 | 1.88 | 1.88 |
| 336.74 | ||
| 244.21 | -3.17 | -3.17 |
| 252.32 | 5.64 | 5.64 |
| 222.24 | 1.24 | 1.24 |
| 278.35 | 6.30 | 6.30 |
| 201.24 | -0.72 | -0.72 |
| 98.14 | 1.33 | 1.33 |
| 415.54 | 4.35 | 4.35 |
| 294.18 | ||
| 248.29 | 4.96 | 4.96 |
| 261.94 | 0.75 | 0.75 |
| 211.65 | 2.07 | 2.07 |
| 220.36 | 4.11 | 4.11 |
| 350.48 | 3.92 | 3.92 |
| 214.27 | 3.03 | 3.03 |
| 252.32 | 5.64 | 5.64 |
| 169.21 | -1.03 | -1.03 |
| 226.32 | 4.25 | 4.25 |
| 78.07 | 0.59 | 0.59 |
| 724.73 | 8.77 | 8.77 |
| 298.00 | ||
| 197.45 | 3.35 | 3.35 |
| 109.94 | 1.31 | 1.31 |
| 296.28 | 3.31 | 3.31 |
| 195.22 | 1.88 | 1.88 |
| 172.21 | -0.73 | -0.73 |
| 546.81 | 11.25 | 11.25 |
| 305.83 | 0.76 | 0.76 |
| 130.20 | 1.37 | 1.37 |
| 358.55 | 6.46 | 6.46 |
| 272.77 | 4.55 | 4.55 |
| 231.89 | 4.01 | 4.01 |
| 226.27 | 2.01 | 2.01 |
| 552.58 | 5.40 | 5.40 |
| 330.21 | 1.69 | 1.69 |
| 927.02 | 4.39 | 4.39 |
| 276.34 | 5.58 | 5.58 |
| 313.32 | 2.94 | 2.94 |
| 213.35 | 3.27 | 3.27 |
| 188.01 | 2.96 | 2.96 |
| 174.20 | 0.89 | 0.89 |
| 411.80 | 5.38 | 5.38 |
| 643.59 | 8.05 | 8.05 |
| 223.49 | 3.41 | 3.41 |
| 785.67 | 9.33 | 9.33 |
| 344.05 | 0.94 | 0.94 |
| 198.22 | 3.83 | 3.83 |
| 298.29 | 0.15 | 0.15 |
| 374.40 | 4.70 | 4.70 |
| 324.79 | 2.04 | 2.04 |
| 306.27 | -1.68 | -1.68 |
| 403.89 | 2.80 | 2.80 |
| 428.12 | 4.40 | 4.40 |
| 639.83 | 5.73 | 5.73 |
| 384.52 | 6.19 | 6.19 |
| 407.62 | 5.46 | 5.46 |
| 302.41 | 4.00 | 4.00 |
| 145.55 | -0.31 | -0.31 |
| 228.29 | 5.15 | 5.15 |
| 207.11 | 2.32 | 2.32 |
| 465.09 | 5.99 | 5.99 |
| 241.87 | 0.48 | 0.48 |
| 914.14 | 5.52 | 5.52 |
| 276.34 | 6.33 | 6.33 |
| 411.17 | ||
| 513.59 | 4.94 | 4.94 |
| 296.56 | 3.26 | 3.26 |
| 1008.26 | 5.60 | 5.60 |
| 514.08 | 5.72 | 5.72 |
| 296.32 | 1.57 | 1.57 |
| 380.78 | 3.65 | 3.65 |
| 142.20 | 1.76 | 1.76 |
| 542.71 | 4.92 | 4.92 |
| 253.09 | 2.09 | 2.09 |
| 204.34 | 2.68 | 2.68 |
| 247.68 | 3.30 | 3.30 |
| 240.22 | 2.72 | 2.72 |
| 349.07 | 3.52 | 3.52 |
| 214.35 | 4.08 | 4.08 |
| 411.33 | 5.94 | 5.94 |
| 502.92 | 7.40 | 7.40 |
| 333.86 | 3.86 | 3.86 |
| 408.38 | 4.17 | 4.17 |
| 158.65 | 3.06 | 3.06 |
| 192.25 | 0.86 | 0.86 |
| 256.43 | 5.25 | 5.25 |
| 577.93 | 6.58 | 6.58 |
| 156.27 | 2.90 | 2.90 |
| 458.83 | 4.56 | 4.56 |
| 290.06 | ||
| 238.36 | 3.56 | 3.56 |
| 274.10 | 2.80 | 2.80 |
| 288.78 | 3.58 | 3.58 |
| 347.00 | ||
| 298.30 | 3.23 | 3.23 |
| 156.22 | 2.08 | 2.08 |
| 268.36 | 4.83 | 4.83 |
| 119.95 | 0.90 | 0.90 |
| 288.33 | 4.09 | 4.09 |
| 492.44 | 1.48 | 1.48 |
| 187.22 | 0.82 | 0.82 |
| 1732.15 |