Assay Report Card

Basic Information

ID: ALA2114909

Type: Functional

Description: PubChem BioAssay. HTS assay for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1: Hit Confirmation. (Class of assay: confirmatory)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
315.764.044.04
506.472.322.32
560.642.412.41
298.32-0.84-0.84
736.946.026.02
392.15-0.77-0.77
462.935.495.49
265.323.253.25
262.301.251.25
366.411.121.12
265.310.500.50
224.263.033.03
325.35-1.74-1.74
320.383.373.37
373.463.033.03
466.544.354.35
336.423.123.12
322.393.063.06
442.553.803.80
244.21-3.17-3.17
284.30-1.27-1.27
409.07
307.383.033.03
507.98-0.79-0.79
393.453.413.41
383.685.345.34
266.232.072.07
599.144.284.28
578.723.943.94
461.522.062.06
477.593.263.26
431.532.582.58
405.484.574.57
507.601.651.65
344.813.393.39
455.544.724.72
397.783.433.43
482.634.164.16
396.413.323.32
528.023.423.42
456.505.385.38
259.313.443.44
361.424.604.60
323.382.712.71
356.823.123.12
434.453.333.33
387.323.963.96
424.503.143.14
472.543.373.37
534.613.093.09
431.903.473.47
426.473.073.07
332.454.124.12
466.584.494.49
478.552.572.57
467.624.664.66
437.554.474.47
480.572.622.62
257.251.661.66
271.353.313.31
384.303.143.14
460.542.492.49
334.403.533.53
511.994.134.13
490.985.265.26
728.78-1.51-1.51
291.143.693.69
522.953.433.43
465.571.791.79
340.342.132.13
457.603.883.88
281.344.324.32
405.522.692.69
461.544.574.57
320.362.702.70
484.573.513.51
418.411.041.04
460.523.103.10
429.523.173.17
519.584.064.06
266.143.213.21
488.594.394.39
456.503.333.33
344.483.923.92
533.584.354.35
437.551.381.38
494.576.246.24
510.593.523.52
333.392.602.60
327.803.353.35
500.624.084.08
388.523.353.35
379.472.642.64
448.645.335.33
491.504.344.34
432.543.373.37
418.501.971.97
426.445.625.62
460.944.214.21
520.542.392.39
487.623.973.97
380.403.023.02
492.532.642.64
408.535.425.42
290.753.373.37
485.014.874.87
545.674.424.42
338.453.223.22
443.964.864.86
487.663.793.79
353.412.722.72
462.505.315.31
534.693.113.11
296.20-0.80-0.80
418.434.264.26
445.572.812.81
308.26-1.04-1.04
388.493.433.43
411.513.273.27
550.650.750.75
494.573.343.34
519.403.753.75
466.582.662.66
352.783.523.52
326.364.014.01
513.573.333.33
489.924.984.98
438.964.374.37
471.624.124.12
443.573.343.34
470.573.983.98
493.993.573.57
237.261.351.35
485.574.894.89
791.085.885.88
251.291.741.74
433.606.026.02
400.502.992.99
573.635.255.25
592.704.324.32
366.463.143.14
412.914.434.43
330.321.551.55
407.433.613.61
336.333.003.00
390.421.201.20
454.503.723.72
427.342.252.25
430.514.004.00
423.224.264.26
378.484.274.27
345.360.960.96
473.470.960.96
515.413.673.67
475.553.083.08
415.523.443.44
450.423.343.34
454.874.064.06
412.473.943.94
414.534.634.63
400.823.443.44
413.493.273.27
422.483.553.55
377.433.193.19
458.563.643.64
360.483.683.68
395.533.933.93
379.464.644.64
428.602.622.62
484.603.933.93
406.452.952.95
452.583.763.76
496.524.244.24
466.224.734.73
365.372.032.03
334.334.714.71
319.294.144.14
363.332.772.77
426.563.543.54
443.434.204.20
333.303.093.09
264.332.722.72
236.301.041.04
364.354.184.18
219.291.931.93
441.553.873.87
428.453.993.99
460.512.792.79
542.465.725.72
421.575.165.16
410.434.144.14
270.363.053.05
322.443.193.19
543.672.962.96
501.544.394.39
408.891.301.30
235.373.123.12
401.431.511.51
347.834.634.63
495.623.793.79
315.403.363.36
332.363.333.33
468.614.244.24
428.512.932.93
494.573.003.00
399.443.023.02
501.515.075.07
399.453.633.63
428.444.034.03
356.352.952.95
312.384.744.74
440.535.015.01
507.504.074.07
396.443.783.78
338.464.024.02
489.965.285.28
488.614.414.41
404.501.901.90
460.534.184.18
539.613.013.01
483.573.283.28
419.483.433.43
355.393.623.62
406.493.023.02
394.334.664.66
319.823.813.81
434.492.792.79
382.425.025.02
341.421.611.61
478.552.392.39
480.615.045.04
462.484.734.73
544.513.083.08
306.373.653.65
474.524.214.21
548.672.292.29
387.872.232.23
335.363.753.75
392.435.065.06
480.605.105.10
474.515.205.20
482.513.563.56
379.414.744.74
346.412.402.40
431.493.453.45
425.553.813.81
523.623.383.38
418.553.973.97
420.515.375.37
276.343.723.72
389.462.162.16
353.382.912.91
621.534.954.95
547.694.794.79
323.615.435.43
339.273.593.59
340.383.873.87
446.593.793.79
337.383.473.47
267.343.023.02
353.393.023.02
310.833.113.11
335.274.874.87
494.573.003.00
544.973.923.92
424.552.762.76
392.452.882.88
309.393.133.13
427.482.322.32
479.582.422.42
474.513.663.66
410.432.722.72
408.454.514.51
405.513.113.11
464.471.991.99
489.654.644.64
420.922.502.50
399.494.024.02
361.472.772.77
378.392.182.18
420.583.973.97
383.405.025.02
420.424.554.55
384.533.323.32
387.483.953.95
447.725.075.07
1009.18
267.283.553.55
374.391.801.80
408.413.063.06
431.532.122.12
333.394.394.39
359.304.404.40
382.903.923.92
277.443.983.98
410.423.713.71
428.543.633.63
326.812.612.61
459.455.565.56
495.014.644.64
382.382.832.83
468.583.833.83
352.514.384.38
478.564.154.15
417.473.183.18
380.474.604.60
438.503.753.75
474.593.723.72
474.514.674.67
445.467.167.16
343.483.973.97
410.433.063.06
342.361.731.73
512.635.535.53
429.554.184.18
328.384.444.44
375.433.183.18
402.464.354.35
423.494.164.16
405.444.034.03
413.503.113.11
295.343.863.86
433.471.591.59
307.354.054.05
523.594.074.07
520.616.966.96
329.814.354.35
477.571.641.64
257.292.192.19
426.492.722.72
443.554.034.03
566.654.164.16
368.433.353.35
429.862.592.59
396.404.754.75
455.504.244.24
295.352.532.53
526.645.255.25
544.612.922.92
432.573.723.72
485.594.014.01
428.543.103.10
448.533.193.19
407.522.352.35
399.504.424.42
473.624.174.17
277.271.101.10
383.454.404.40
447.634.604.60
386.843.423.42
419.494.004.00
433.492.182.18
404.404.164.16
453.501.631.63
397.431.931.93
467.603.443.44
336.351.921.92
514.614.114.11
362.412.622.62
543.553.623.62
305.392.442.44
476.582.352.35
435.490.930.93
488.654.194.19
271.364.364.36
430.573.193.19
333.353.343.34
475.504.534.53
493.564.534.53
373.681.511.51
404.485.025.02
450.543.433.43
386.414.024.02
451.485.105.10
491.494.704.70
431.495.395.39
431.493.313.31
424.433.903.90
397.313.143.14
326.793.793.79
437.744.854.85
356.422.642.64
355.322.602.60
531.635.045.04
494.645.355.35
455.552.402.40
492.604.154.15
415.904.214.21
329.403.133.13
462.935.495.49
578.784.764.76
409.443.463.46
309.444.154.15
415.491.911.91
402.504.394.39
342.403.843.84
581.652.682.68
312.313.483.48
398.514.564.56
434.512.582.58
480.633.983.98
444.634.114.11
422.553.873.87
447.373.983.98
531.615.155.15
386.453.023.02
416.543.893.89
548.672.432.43
344.442.692.69
410.423.713.71
494.642.742.74
443.883.903.90
356.433.013.01
574.632.522.52
425.553.943.94
391.543.223.22
390.782.302.30
399.523.093.09
375.452.972.97
392.883.743.74
555.427.067.06
337.384.084.08
470.004.184.18
436.532.802.80
412.543.553.55
238.292.822.82
462.553.583.58
386.464.364.36
492.594.464.46
492.042.932.93
378.904.014.01
487.653.253.25
582.693.033.03
440.553.163.16
417.482.782.78
350.213.403.40
417.563.163.16
443.453.563.56
404.394.374.37
478.502.172.17
472.544.324.32
586.68-1.44-1.44
412.483.693.69
368.412.722.72
554.695.765.76
253.262.202.20
501.565.165.16
495.623.433.43
523.642.592.59
467.572.812.81
518.532.792.79
323.353.043.04
304.372.752.75
388.543.083.08
386.344.784.78
495.544.484.48
534.594.054.05
558.565.835.83
452.562.352.35
497.585.895.89
540.015.295.29
248.713.033.03
384.383.223.22
272.263.153.15
452.462.592.59
439.562.372.37
432.554.244.24
570.553.053.05
575.663.883.88
435.483.413.41
345.794.104.10
497.004.094.09
384.362.932.93
416.363.953.95
237.261.351.35
407.343.403.40
478.654.654.65
462.444.974.97
472.504.374.37
469.563.813.81
427.553.703.70
359.403.753.75
429.554.184.18
382.293.803.80
431.502.692.69
292.723.103.10
744.813.853.85
501.654.364.36
370.452.542.54
572.684.764.76
578.714.114.11
472.593.953.95
647.693.543.54
525.684.424.42
359.250.570.57
423.922.032.03
579.624.624.62
366.372.532.53
772.864.634.63
614.794.784.78
480.524.844.84
388.522.822.82
486.491.801.80
454.964.074.07
396.451.271.27
613.645.735.73
542.672.942.94
667.715.635.63
630.622.152.15
510.613.653.65
529.493.283.28
504.624.304.30
583.443.883.88
369.474.084.08
448.574.424.42
478.502.302.30
600.735.265.26
559.133.703.70
487.385.155.15
422.403.633.63
407.491.091.09
542.603.193.19
347.401.171.17
526.974.314.31
386.372.932.93
449.962.322.32
510.632.532.53
390.422.422.42
500.522.192.19
487.562.312.31
657.655.465.46
396.493.943.94
459.543.693.69
458.582.032.03
439.592.402.40
475.546.736.73
440.522.482.48
501.585.535.53
450.451.681.68
445.541.321.32
653.537.017.01
405.462.912.91
454.503.053.05
480.573.433.43
548.645.935.93
466.543.303.30
367.414.094.09
612.655.275.27
618.585.375.37
577.664.514.51
454.523.973.97
548.745.255.25
572.684.764.76
344.873.763.76
463.291.401.40
473.253.103.10
800.925.415.41
356.403.273.27
455.513.663.66
446.514.964.96
402.955.365.36
586.705.155.15
758.844.244.24
524.663.263.26
370.433.663.66
489.623.133.13
475.613.133.13
380.452.042.04
440.574.124.12
444.543.153.15
474.113.813.81
398.534.634.63
459.633.573.57
503.154.594.59
366.433.143.14
394.434.344.34
379.212.942.94
401.502.962.96
357.402.862.86
389.463.643.64
780.952.222.22
256.26-0.99-0.99
444.522.832.83
411.875.375.37
485.534.204.20
529.564.114.11
387.422.872.87
447.372.312.31
350.331.681.68
482.924.664.66
569.713.033.03
321.413.573.57
311.373.163.16
324.342.212.21
370.253.633.63
601.414.344.34
348.432.032.03
389.534.754.75
622.572.432.43
435.494.564.56
435.494.564.56
321.342.012.01
355.444.164.16
501.595.165.16
334.442.972.97
475.504.144.14
287.392.892.89
430.462.832.83
517.564.044.04
455.563.153.15
336.421.501.50
455.562.982.98
230.230.730.73
410.433.583.58
450.513.823.82
379.464.274.27
457.493.633.63
500.615.765.76
493.573.963.96