Basic Information
ID: ALA2114921
Type: Functional
Description: PubChem BioAssay. InCell qHTS Assay for Inhibitors of the mTORC1 Signaling Pathway in MEF (Tsc2-/-, p53-/-) Cells: Hit Validation. (Class of assay: confirmatory)
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase mTOR(ALA2842)
Document: ALA1201862
PubChem Source: AID:651791
Activity Charts
Bioactivity
Activity Types for Assay ALA2114921
Potency
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.55 | 3.16 | 3.16 |
| 463.41 | 4.15 | 4.15 |
| 408.55 | 3.16 | 3.16 |
| 414.29 | 4.96 | 4.96 |
| 416.64 | 4.31 | 4.31 |
| 454.50 | 2.83 | 2.83 |
| 469.95 | 5.74 | 5.74 |
| 440.63 | 6.51 | 6.51 |
| 406.36 | 5.34 | 5.34 |
| 441.98 | 5.79 | 5.79 |
| 416.32 | 4.23 | 4.23 |
| 437.93 | 3.33 | 3.33 |
| 446.59 | 5.17 | 5.17 |
| 286.71 | 4.13 | 4.13 |
| 325.78 | 2.09 | 2.09 |
| 433.89 | 4.11 | 4.11 |
| 400.95 | 4.29 | 4.29 |
| 431.94 | 3.49 | 3.49 |
| 432.39 | 4.80 | 4.80 |
| 402.41 | 4.46 | 4.46 |
| 498.35 | 6.19 | 6.19 |
| 403.94 | 3.71 | 3.71 |
| 403.87 | 4.66 | 4.66 |
| 420.54 | 5.37 | 5.37 |
| 317.39 | 5.26 | 5.26 |
| 395.43 | 3.11 | 3.11 |
| 579.72 | 4.35 | 4.35 |
| 494.98 | 3.00 | 3.00 |
| 408.55 | 3.16 | 3.16 |
| 469.51 | 5.96 | 5.96 |
| 423.83 | 3.63 | 3.63 |
| 526.61 | 5.75 | 5.75 |
| 328.44 | 3.45 | 3.45 |
| 396.49 | 4.88 | 4.88 |
| 429.33 | 2.54 | 2.54 |
| 512.72 | 7.12 | 7.12 |
| 433.89 | 4.11 | 4.11 |
| 416.57 | 5.08 | 5.08 |
| 344.21 | 3.80 | 3.80 |
| 429.54 | 5.48 | 5.48 |
| 430.46 | 3.93 | 3.93 |
| 362.93 | 4.78 | 4.78 |
| 376.87 | 3.57 | 3.57 |
| 341.21 | 2.03 | 2.03 |
| 417.98 | 5.79 | 5.79 |
| 453.56 | 3.69 | 3.69 |
| 474.95 | 3.97 | 3.97 |
| 432.61 | 3.89 | 3.89 |
| 492.62 | 3.10 | 3.10 |
| 412.54 | 5.27 | 5.27 |
| 339.82 | 5.24 | 5.24 |
| 292.33 | 1.27 | 1.27 |
| 306.36 | 1.58 | 1.58 |
| 378.43 | 6.21 | 6.21 |
| 427.45 | 3.63 | 3.63 |
| 445.93 | 3.78 | 3.78 |
| 606.21 | 6.32 | 6.32 |
| 381.51 | 3.82 | 3.82 |
| 477.75 | 7.32 | 7.32 |
| 458.91 | 5.98 | 5.98 |
| 450.54 | 4.55 | 4.55 |
| 424.91 | 1.89 | 1.89 |
| 459.91 | 3.53 | 3.53 |
| 427.46 | 0.34 | 0.34 |
| 440.31 | 3.62 | 3.62 |
| 360.26 | 3.78 | 3.78 |
| 383.26 | 3.44 | 3.44 |
| 445.93 | 3.78 | 3.78 |
| 581.76 | 3.62 | 3.62 |
| 474.33 | 3.87 | 3.87 |
| 434.58 | 5.03 | 5.03 |
| 577.50 | 5.39 | 5.39 |
| 460.97 | 3.97 | 3.97 |
| 424.53 | 4.86 | 4.86 |
| 471.54 | 4.93 | 4.93 |
| 604.66 | 4.43 | 4.43 |
| 434.58 | 5.03 | 5.03 |
| 402.61 | 3.92 | 3.92 |
| 417.42 | 5.04 | 5.04 |
| 551.65 | 4.94 | 4.94 |
| 431.52 | 4.88 | 4.88 |
| 305.38 | 4.58 | 4.58 |
| 393.87 | 5.25 | 5.25 |
| 540.09 | 5.27 | 5.27 |
| 467.57 | 3.70 | 3.70 |
| 397.54 | 3.90 | 3.90 |
| 506.93 | 5.93 | 5.93 |
| 446.60 | 5.37 | 5.37 |
| 429.86 | 6.36 | 6.36 |
| 382.49 | 4.10 | 4.10 |
| 309.41 | 3.89 | 3.89 |
| 407.42 | 5.10 | 5.10 |
| 468.64 | 3.69 | 3.69 |
| 415.90 | 3.97 | 3.97 |
| 451.96 | 3.64 | 3.64 |
| 433.94 | 4.95 | 4.95 |
| 306.36 | 1.66 | 1.66 |
| 371.57 | 3.66 | 3.66 |
| 439.31 | 3.79 | 3.79 |
| 399.51 | 4.74 | 4.74 |