Basic Information
ID: ALA2114932
Type: Functional
Description: PubChem BioAssay. Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay. (Class of assay: confirmatory)
Format: BAO_0000019
Organism: Homo sapiens
Target: Fatty acid synthase(ALA4158)
Document: ALA1201862
PubChem Source: AID:624326
Activity Charts
Bioactivity
Activity Types for Assay ALA2114932
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.36 | 2.93 | 2.93 |
| 386.43 | 3.32 | 3.32 |
| 431.56 | 2.89 | 2.89 |
| 533.38 | 4.61 | 4.61 |
| 454.27 | 3.53 | 3.53 |
| 374.19 | 3.42 | 3.42 |
| 313.29 | 2.80 | 2.80 |
| 305.33 | 2.73 | 2.73 |
| 445.43 | 4.01 | 4.01 |
| 368.44 | 3.29 | 3.29 |
| 433.58 | 3.76 | 3.76 |
| 280.28 | 3.41 | 3.41 |
| 480.44 | 3.34 | 3.34 |
| 308.40 | 3.38 | 3.38 |
| 567.68 | 3.00 | 3.00 |
| 366.31 | 1.13 | 1.13 |
| 291.24 | 1.24 | 1.24 |
| 359.86 | 4.73 | 4.73 |
| 439.83 | 4.57 | 4.57 |
| 443.53 | 2.48 | 2.48 |
| 405.50 | 4.19 | 4.19 |
| 483.46 | 3.91 | 3.91 |
| 452.47 | 4.26 | 4.26 |
| 345.38 | 2.53 | 2.53 |
| 328.28 | 3.10 | 3.10 |
| 340.30 | 2.57 | 2.57 |
| 310.34 | 4.83 | 4.83 |
| 396.45 | 2.29 | 2.29 |
| 439.45 | 3.64 | 3.64 |
| 319.36 | 3.12 | 3.12 |
| 411.31 | 4.96 | 4.96 |
| 550.55 | 4.14 | 4.14 |
| 320.35 | 2.52 | 2.52 |
| 442.48 | 4.19 | 4.19 |
| 374.68 | 4.73 | 4.73 |
| 329.31 | 3.21 | 3.21 |
| 344.39 | 0.99 | 0.99 |
| 364.41 | 3.16 | 3.16 |
| 293.42 | 2.72 | 2.72 |
| 458.99 | 2.60 | 2.60 |
| 355.39 | 3.30 | 3.30 |
| 405.50 | 3.24 | 3.24 |
| 363.29 | 3.04 | 3.04 |
| 364.38 | 2.02 | 2.02 |
| 478.68 | 5.60 | 5.60 |
| 333.33 | 2.45 | 2.45 |
| 464.50 | 2.54 | 2.54 |
| 419.72 | 4.28 | 4.28 |
| 367.41 | 3.23 | 3.23 |
| 400.42 | 2.08 | 2.08 |
| 371.49 | 3.66 | 3.66 |
| 357.62 | 5.09 | 5.09 |
| 366.74 | 2.78 | 2.78 |
| 350.35 | 3.04 | 3.04 |
| 410.52 | 1.56 | 1.56 |
| 358.44 | 2.89 | 2.89 |
| 340.34 | 2.34 | 2.34 |
| 359.29 | 2.09 | 2.09 |
| 333.35 | 3.83 | 3.83 |
| 429.43 | 1.91 | 1.91 |
| 570.87 | 5.32 | 5.32 |
| 353.45 | 2.97 | 2.97 |
| 582.70 | 6.12 | 6.12 |
| 447.46 | 4.31 | 4.31 |
| 340.41 | 3.07 | 3.07 |
| 381.39 | 2.68 | 2.68 |
| 438.51 | 2.22 | 2.22 |
| 472.51 | 3.02 | 3.02 |
| 368.42 | 3.39 | 3.39 |
| 358.46 | 4.66 | 4.66 |
| 562.00 | 4.05 | 4.05 |
| 344.44 | 4.49 | 4.49 |
| 471.56 | 3.37 | 3.37 |
| 277.73 | 3.88 | 3.88 |
| 380.87 | 4.86 | 4.86 |
| 422.53 | 1.52 | 1.52 |
| 264.32 | 3.97 | 3.97 |
| 331.37 | 2.40 | 2.40 |
| 527.69 | 1.46 | 1.46 |
| 392.54 | 3.60 | 3.60 |
| 312.32 | 3.10 | 3.10 |
| 369.38 | 2.10 | 2.10 |
| 525.94 | 5.78 | 5.78 |
| 330.39 | 2.97 | 2.97 |
| 327.38 | 3.43 | 3.43 |
| 395.17 | 2.23 | 2.23 |
| 403.52 | 4.88 | 4.88 |
| 419.52 | 4.58 | 4.58 |
| 329.78 | 3.86 | 3.86 |
| 377.35 | 3.02 | 3.02 |
| 318.29 | 2.60 | 2.60 |
| 619.81 | 3.05 | 3.05 |
| 298.30 | 3.86 | 3.86 |
| 541.67 | 5.61 | 5.61 |
| 481.51 | 4.35 | 4.35 |
| 437.16 | 4.52 | 4.52 |
| 296.37 | 4.13 | 4.13 |
| 393.81 | 3.70 | 3.70 |
| 451.53 | 3.44 | 3.44 |
| 346.16 | 4.83 | 4.83 |