Assay Report Card

Basic Information

ID: ALA2114932

Type: Functional

Description: PubChem BioAssay. Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay. (Class of assay: confirmatory)

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.916.616.61
494.088.018.01
457.394.404.40
252.140.860.86
302.133.623.62
400.362.932.93
347.372.962.96
329.354.004.00
436.323.423.42
447.924.064.06
287.174.564.56
287.283.253.25
317.283.803.80
386.433.323.32
405.453.933.93
431.562.892.89
441.333.643.64
324.384.354.35
296.753.563.56
488.595.205.20
276.120.820.82
481.405.175.17
330.343.403.40
464.502.542.54
273.303.813.81
328.373.353.35
403.402.902.90
334.362.122.12
533.384.614.61
341.753.473.47
488.554.694.69
371.422.982.98
381.504.164.16
553.662.622.62
344.762.952.95
306.673.233.23
400.863.443.44
382.844.244.24
355.444.644.64
455.252.932.93
477.474.034.03
349.773.703.70
391.383.283.28
498.493.843.84
454.273.533.53
306.322.192.19
438.524.064.06
562.455.435.43
391.421.991.99
439.503.763.76
313.744.414.41
524.086.836.83
346.383.053.05
374.193.423.42
414.331.751.75
457.511.931.93
588.905.205.20
306.673.233.23
440.914.744.74
337.785.065.06
356.383.293.29
492.511.581.58
351.362.672.67
301.373.543.54
521.572.842.84
430.463.933.93
363.803.203.20
489.623.193.19
372.223.503.50
324.312.802.80
312.364.914.91
459.552.852.85
381.414.164.16
397.743.813.81
376.874.314.31
313.292.802.80
469.563.283.28
459.443.473.47
363.351.621.62
478.303.303.30
429.904.974.97
427.984.314.31
403.453.693.69
497.532.912.91
358.743.213.21
472.594.274.27
345.472.672.67
321.291.741.74
480.962.612.61
422.492.992.99
305.332.732.73
379.853.283.28
345.793.213.21
431.422.602.60
376.413.283.28
470.553.433.43
356.432.272.27
357.373.333.33
292.291.811.81
445.434.014.01
437.564.274.27
426.492.652.65
415.402.242.24
368.311.671.67
484.516.256.25
419.822.882.88
397.433.293.29
470.553.433.43
484.582.602.60
423.543.963.96
318.763.613.61
353.423.353.35
470.554.334.33
368.443.293.29
412.413.763.76
491.504.344.34
306.322.192.19
398.875.725.72
461.014.354.35
368.442.972.97
322.793.803.80
433.583.763.76
413.432.472.47
391.834.744.74
280.283.413.41
422.783.693.69
473.512.702.70
457.563.983.98
297.313.193.19
539.554.784.78
622.763.673.67
349.184.044.04
365.353.553.55
403.496.256.25
392.422.672.67
356.383.103.10
448.572.492.49
312.344.024.02
375.812.732.73
413.431.951.95
400.433.293.29
418.453.673.67
334.353.273.27
442.463.913.91
431.903.753.75
346.382.942.94
350.331.601.60
426.832.602.60
601.703.413.41
489.375.155.15
527.692.372.37
432.503.093.09
421.362.512.51
419.462.042.04
435.383.593.59
480.443.343.34
449.461.391.39
451.553.933.93
374.314.004.00
496.573.633.63
399.883.873.87
436.521.941.94
308.403.383.38
318.334.224.22
307.744.464.46
665.386.126.12
567.683.003.00
366.311.131.13
308.403.263.26
350.763.073.07
510.304.474.47
426.524.464.46
416.573.453.45
427.532.512.51
319.342.642.64
298.343.353.35
341.254.144.14
446.625.065.06
305.332.732.73
286.291.381.38
328.442.672.67
291.404.284.28
329.743.313.31
454.481.821.82
420.812.282.28
419.873.803.80
426.472.442.44
479.564.074.07
426.864.394.39
475.592.952.95
302.373.713.71
355.493.713.71
417.922.992.99
291.241.241.24
468.293.213.21
447.942.862.86
434.993.223.22
418.485.145.14
419.284.244.24
315.403.653.65
401.435.815.81
318.763.613.61
359.864.734.73
439.834.574.57
411.314.964.96
308.163.773.77
501.384.834.83
447.742.702.70
415.524.174.17
403.403.213.21
406.422.772.77
486.644.634.63
308.343.613.61
407.472.202.20
348.743.073.07
392.463.143.14
344.172.682.68
324.383.693.69
383.451.981.98
296.393.163.16
378.455.385.38
487.823.903.90
334.332.612.61
443.532.482.48
405.504.194.19
293.322.922.92
361.232.702.70
403.923.973.97
436.584.944.94
378.445.085.08
354.412.912.91
270.723.623.62
419.394.064.06
432.555.655.65
385.463.133.13
340.382.362.36
379.035.465.46
531.52
327.342.032.03
483.463.913.91
369.463.613.61
679.802.082.08
427.463.103.10
458.583.193.19
282.323.893.89
347.352.492.49
324.383.863.86
470.534.404.40
268.323.043.04
412.452.072.07
343.343.263.26
305.332.252.25
366.303.663.66
471.583.213.21
456.463.943.94
450.633.273.27
313.312.952.95
362.772.762.76
551.625.265.26
360.322.782.78
403.351.521.52
414.373.163.16
487.002.742.74
452.474.264.26
326.742.462.46
345.382.532.53
312.373.693.69
328.283.103.10
281.363.713.71
445.934.064.06
440.461.661.66
376.414.764.76
262.383.603.60
381.392.222.22
276.323.463.46
435.431.001.00
340.302.572.57
476.534.004.00
412.423.693.69
355.373.103.10
372.395.385.38
458.432.372.37
417.214.824.82
310.344.834.83
396.452.292.29
439.453.643.64
321.384.434.43
365.144.174.17
430.263.493.49
414.872.372.37
284.313.563.56
356.172.382.38
392.784.334.33
385.422.792.79
334.373.443.44
367.233.593.59
372.382.512.51
384.504.594.59
370.413.583.58
487.515.005.00
319.363.123.12
439.863.713.71
472.511.451.45
474.623.213.21
428.452.562.56
353.374.734.73
422.442.502.50
494.983.003.00
411.314.964.96
550.554.144.14
455.895.075.07
399.382.982.98
552.013.853.85
403.493.443.44
462.284.934.93
405.413.323.32
400.422.082.08
297.743.573.57
290.343.863.86
392.364.064.06
317.463.423.42
345.402.722.72
391.422.042.04
539.661.821.82
426.544.324.32
484.493.673.67
320.352.522.52
442.484.194.19
320.354.374.37
498.933.963.96
378.333.533.53
305.292.862.86
374.684.734.73
527.453.273.27
436.493.713.71
335.312.052.05
401.813.843.84
363.373.843.84
447.395.075.07
386.432.562.56
329.313.213.21
358.382.022.02
444.972.212.21
285.333.633.63
344.390.990.99
388.314.124.12
411.412.232.23
314.804.724.72
339.183.873.87
355.393.533.53
364.413.163.16
308.384.304.30
293.422.722.72
457.554.164.16
312.381.571.57
345.453.123.12
477.955.995.99
458.992.602.60
318.763.613.61
355.393.303.30
284.320.790.79
310.273.443.44
314.212.272.27
446.944.274.27
313.793.123.12
405.503.243.24
291.353.833.83
345.310.710.71
393.424.894.89
519.405.165.16
364.362.872.87
383.403.243.24
345.832.162.16
263.302.422.42
378.413.393.39
400.352.772.77
452.452.192.19
363.293.043.04
324.373.743.74
430.874.434.43
423.502.512.51
413.523.313.31
515.613.803.80
385.514.054.05
367.473.773.77
404.253.333.33
346.353.993.99
406.343.313.31
359.402.842.84
431.583.883.88
364.382.022.02
478.685.605.60
334.753.743.74
390.193.603.60
353.363.983.98
361.403.203.20
284.313.473.47
320.373.913.91
323.354.724.72
434.453.783.78
529.644.114.11
324.384.004.00
489.532.602.60
489.944.594.59
411.463.813.81
435.874.654.65
367.413.233.23
341.373.463.46
468.563.323.32
587.673.973.97
498.614.194.19
422.554.634.63
342.874.644.64
413.432.642.64
395.462.302.30
400.392.482.48
499.604.184.18
413.432.682.68
374.782.992.99
332.362.662.66
449.463.213.21
441.473.443.44
354.362.722.72
326.333.753.75
373.914.654.65
451.873.463.46
462.493.993.99
499.604.184.18
440.294.444.44
367.795.245.24
372.382.602.60
358.312.042.04
326.312.652.65
406.573.693.69
341.372.072.07
446.513.053.05
333.332.452.45
497.854.754.75
457.552.972.97
360.373.653.65
464.502.542.54
421.412.512.51
406.444.774.77
382.492.812.81
616.515.365.36
325.322.672.67
337.384.444.44
312.374.454.45
304.352.982.98
342.401.841.84
419.724.284.28
341.372.972.97
404.884.354.35
338.414.114.11
415.432.022.02
442.793.283.28
367.413.233.23
408.363.543.54
380.813.733.73
479.585.185.18
299.312.932.93
477.415.085.08
318.104.524.52
400.422.082.08
371.493.663.66
433.423.843.84
322.183.993.99
306.713.513.51
329.403.983.98
505.643.003.00
465.264.124.12
345.332.802.80
326.742.462.46
357.625.095.09
366.742.782.78
405.843.503.50
308.343.563.56
445.484.264.26
494.503.483.48
334.342.862.86
387.463.043.04
408.463.313.31
455.453.353.35
243.293.223.22
392.244.924.92
366.423.703.70
316.813.513.51
393.443.843.84
350.353.043.04
410.521.561.56
432.515.535.53
441.244.834.83
287.343.783.78
419.553.373.37
386.402.962.96
567.09
355.224.744.74
309.322.972.97
467.482.582.58
348.342.362.36
426.904.764.76
429.862.592.59
484.944.784.78
548.283.433.43
459.924.114.11
400.442.692.69
388.352.612.61
405.452.382.38
491.603.943.94
336.342.142.14
422.421.951.95
410.353.813.81
427.463.353.35
358.442.892.89
441.874.764.76
353.213.203.20
335.361.541.54
381.233.623.62
404.852.612.61
340.342.342.34
314.323.113.11
428.433.523.52
494.224.804.80
296.333.693.69
398.464.244.24
401.424.094.09
358.364.654.65
359.292.092.09
413.432.252.25
351.264.854.85
611.794.364.36
302.332.772.77
267.353.403.40
331.803.703.70
331.352.172.17
388.451.091.09
417.563.493.49
333.353.833.83
304.313.083.08
391.472.152.15
529.644.114.11
372.383.123.12
409.532.962.96
310.784.094.09
443.984.234.23
370.413.373.37
324.384.014.01
392.463.143.14
428.464.534.53
471.493.453.45
423.921.931.93
309.332.972.97
387.492.892.89
346.312.852.85
492.695.685.68
381.342.872.87
360.373.173.17
336.341.781.78
478.513.613.61
441.515.175.17
316.413.283.28
381.353.183.18
457.553.113.11
429.431.911.91
380.374.294.29
424.863.923.92
355.373.103.10
569.681.911.91
431.863.923.92
480.374.244.24
469.284.004.00
392.374.054.05
428.881.361.36
501.542.742.74
367.453.913.91
379.391.531.53
417.392.042.04
335.414.154.15
328.263.043.04
302.322.752.75
349.321.641.64
344.322.042.04
460.164.964.96
452.543.143.14
410.593.943.94
374.444.344.34
677.855.625.62
399.403.003.00
733.782.082.08
570.875.325.32
421.884.104.10
459.924.114.11
361.483.753.75
353.452.972.97
379.463.073.07
500.863.813.81
394.785.625.62
587.673.023.02
582.706.126.12
275.303.623.62
354.371.851.85
353.854.144.14
436.312.992.99
379.212.452.45
434.413.713.71
313.383.353.35
382.754.184.18
387.461.911.91
451.553.823.82
388.513.173.17
447.464.314.31
340.413.073.07
390.443.973.97
385.24
303.334.404.40
367.794.494.49
541.653.433.43
403.372.372.37
431.503.203.20
459.553.093.09
314.733.683.68
331.352.222.22
455.493.833.83
416.431.931.93
491.343.213.21
383.455.045.04
403.453.323.32
383.404.744.74
358.473.073.07
395.512.432.43
428.923.213.21
381.392.682.68
368.214.234.23
386.493.513.51
363.214.414.41
379.392.692.69
468.512.212.21
327.342.782.78
460.282.992.99
498.611.161.16
333.392.552.55
325.373.763.76
438.512.222.22
472.513.023.02
404.424.064.06
482.404.894.89
346.302.392.39
402.763.813.81
449.304.474.47
497.962.392.39
330.302.402.40
368.423.393.39
358.464.664.66
449.472.782.78
328.804.654.65
418.454.454.45
378.413.073.07
284.312.962.96
562.004.054.05
357.203.833.83
432.786.236.23
341.413.813.81
364.364.024.02
410.383.133.13
350.834.684.68
385.604.164.16
320.332.132.13
406.884.644.64
482.923.113.11
484.424.484.48
469.524.134.13
467.555.315.31
381.462.832.83
484.513.093.09
368.402.242.24
401.363.453.45
427.463.153.15
233.231.611.61
301.373.543.54
451.382.832.83
402.392.492.49
340.342.732.73
402.402.812.81
650.966.026.02
391.421.851.85
396.493.513.51
388.453.513.51
431.883.143.14
631.375.925.92
359.483.033.03
360.584.314.31
436.472.982.98
344.444.494.49
364.193.453.45
504.913.963.96
426.864.394.39
273.312.912.91
319.303.063.06
499.955.415.41
348.323.203.20
419.482.772.77
410.473.913.91
344.363.513.51
503.612.942.94
332.383.253.25
308.773.873.87
471.563.373.37
474.451.821.82
298.343.353.35
403.923.973.97
331.352.222.22
398.345.585.58
401.554.164.16
461.474.904.90
328.393.523.52
312.322.562.56
361.793.273.27
471.523.623.62
350.904.224.22
430.412.492.49
392.515.285.28
329.312.482.48
385.252.852.85
414.403.133.13
463.404.154.15
384.345.005.00
384.393.493.49
392.553.523.52
376.874.314.31
306.673.233.23
498.433.223.22
389.502.712.71
277.733.883.88
380.874.864.86
422.531.521.52
264.323.973.97
512.591.931.93
370.362.472.47
413.432.792.79
391.812.482.48
396.834.534.53
440.934.044.04
544.630.750.75
374.213.213.21
491.934.614.61
446.454.674.67
492.094.244.24
277.712.432.43
466.393.083.08
380.873.773.77
646.235.015.01
679.802.082.08
657.864.934.93
414.412.872.87
388.742.772.77
333.272.932.93
624.565.295.29
482.523.183.18
694.805.955.95
347.402.392.39
478.583.153.15
471.434.894.89
595.704.254.25
564.644.324.32
526.836.076.07
644.815.025.02
387.372.082.08
551.694.524.52
403.351.771.77
365.422.902.90
387.352.702.70
517.053.963.96
579.624.624.62
685.874.314.31
968.8513.5913.59
385.382.092.09
592.784.534.53
368.823.813.81
398.423.033.03
391.421.851.85
444.303.053.05
520.561.311.31
473.552.482.48
331.372.402.40
527.691.461.46
392.543.603.60
433.853.193.19
345.382.962.96
403.491.211.21
619.695.545.54
541.746.746.74
641.814.374.37
344.414.504.50
431.541.941.94
418.763.513.51
577.704.394.39
643.665.745.74
516.504.004.00
349.813.393.39
691.275.595.59
369.422.602.60
405.452.092.09
312.323.103.10
523.532.712.71
369.382.102.10
608.783.763.76
408.546.126.12
656.824.944.94
431.493.993.99
613.645.735.73
314.343.703.70
371.393.083.08
470.913.823.82
525.945.785.78
436.543.223.22
514.523.953.95
487.513.043.04
489.314.734.73
474.945.055.05
463.494.054.05
473.535.435.43
291.293.623.62
614.794.014.01
330.392.972.97
429.543.063.06
507.573.473.47
404.442.742.74
313.311.341.34
515.614.774.77
299.404.664.66
371.212.162.16
390.315.375.37
411.483.723.72
581.714.534.53
400.485.025.02
591.803.673.67
604.485.495.49
654.253.713.71
392.453.023.02
519.784.574.57
586.734.514.51
431.541.321.32
342.444.264.26
511.883.583.58
354.394.064.06
410.834.694.69
339.783.713.71
509.614.774.77
340.183.253.25
428.363.463.46
484.385.955.95
510.304.474.47
459.593.253.25
405.452.382.38
562.764.524.52
357.372.202.20
420.345.555.55
456.934.114.11
423.505.295.29
442.394.794.79
404.473.013.01
338.343.873.87
508.542.992.99
380.544.084.08
409.804.694.69
483.495.675.67
614.835.615.61
406.913.723.72
413.565.275.27
470.582.962.96
464.552.432.43
420.445.625.62
406.422.252.25
397.254.294.29
370.454.554.55
628.074.184.18
419.915.295.29
616.764.524.52
350.373.053.05
570.694.134.13
414.984.744.74
394.822.832.83
376.244.324.32
467.364.234.23
361.363.663.66
439.542.972.97
421.483.653.65
382.383.063.06
480.593.003.00
298.293.673.67
327.383.433.43
395.172.232.23
440.243.383.38
472.953.483.48
484.144.934.93
395.172.232.23
450.483.593.59
455.997.007.00
379.292.932.93
380.362.932.93
342.742.922.92
317.504.114.11
375.215.405.40
392.213.893.89
403.524.884.88
419.524.584.58
329.783.863.86
377.353.023.02
466.352.902.90
704.854.524.52
664.775.945.94
433.554.894.89
318.292.602.60
328.413.733.73
321.774.024.02
690.865.655.65
399.401.901.90
510.304.474.47
348.404.004.00
510.972.822.82
365.351.781.78
453.975.245.24
375.474.104.10
369.294.504.50
391.383.283.28
366.182.012.01
384.393.493.49
564.683.703.70
564.664.904.90
403.524.884.88
465.583.723.72
644.865.625.62
345.773.613.61
410.463.843.84
333.372.492.49
392.412.772.77
388.224.054.05
619.813.053.05
298.303.863.86
541.675.615.61
478.685.605.60
396.362.432.43
394.470.830.83
479.574.604.60
433.554.894.89
449.945.305.30
363.394.134.13
419.524.584.58
423.945.235.23
351.203.633.63
496.592.702.70
481.514.354.35
396.363.043.04
410.393.353.35
437.164.524.52
385.402.252.25
376.212.032.03
316.271.471.47
467.533.153.15
357.794.564.56
372.762.922.92
375.215.405.40
498.543.153.15
296.374.134.13
324.680.700.70
342.244.774.77
311.302.952.95
498.503.223.22
486.442.572.57
393.813.703.70
349.321.641.64
458.272.762.76
436.382.592.59
436.453.283.28
325.244.314.31
334.382.072.07
419.284.564.56
339.784.344.34
531.533.783.78
449.263.323.32
451.533.443.44
436.333.323.32
416.282.622.62
290.753.523.52
398.422.272.27
399.864.624.62
483.283.873.87
303.281.401.40
473.535.435.43
374.741.851.85
442.374.034.03
354.371.791.79
350.332.922.92
435.232.932.93
333.353.813.81
404.813.133.13
374.331.621.62
340.301.201.20
374.332.312.31
367.504.924.92
481.453.193.19
346.164.834.83
370.432.992.99
446.463.003.00
390.782.822.82
410.522.722.72
417.873.283.28
585.733.643.64
428.451.291.29
333.733.843.84
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