Basic Information
ID: ALA2148657
Type: Binding
Description: Inhibition of CYP26A1-mediated retinoic acid metabolism in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation counting
Organism: Homo sapiens
Cell type: MCF7
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2148657
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.43 | 4.42 | 4.42 |
| 393.44 | 4.14 | 4.14 |
| 367.42 | 4.55 | 4.55 |
| 383.88 | 5.07 | 5.07 |
| 363.46 | 4.72 | 4.72 |
| 417.43 | 5.43 | 5.43 |
| 379.46 | 4.42 | 4.42 |
| 374.44 | 4.29 | 4.29 |
| 394.43 | 4.32 | 4.32 |
| 439.51 | 4.44 | 4.44 |
| 407.51 | 5.04 | 5.04 |
| 429.32 | 4.57 | 4.57 |
| 430.31 | 3.97 | 3.97 |
| 394.43 | 3.54 | 3.54 |
| 363.46 | 4.72 | 4.72 |
| 407.47 | 4.45 | 4.45 |