Basic Information
ID: ALA2148736
Type: Functional
Description: Antagonist activity at TLR7 expressed in HEK293 cells co-transfected with NF-kappaB/sAP gene assessed as inhibition of gardiquimod-induced NF-kappaB activation up to 250 uM by reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2148736
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 291.40 | 4.75 | 4.75 |
| 315.42 | 5.36 | 5.36 |
| 266.35 | 3.61 | 3.61 |
| 265.36 | 4.21 | 4.21 |
| 279.39 | 4.14 | 4.14 |
| 280.38 | 3.53 | 3.53 |
| 316.41 | 4.76 | 4.76 |
| 365.48 | 6.52 | 6.52 |
| 366.47 | 5.91 | 5.91 |
| 292.39 | 4.14 | 4.14 |
| 305.43 | 4.67 | 4.67 |
| 306.41 | 4.06 | 4.06 |
| 341.46 | 5.90 | 5.90 |
| 342.45 | 5.29 | 5.29 |
| 391.52 | 7.05 | 7.05 |
| 392.51 | 6.45 | 6.45 |
| 299.38 | 4.61 | 4.61 |
| 300.37 | 4.01 | 4.01 |
| 313.40 | 4.54 | 4.54 |
| 314.39 | 3.93 | 3.93 |
| 349.44 | 5.77 | 5.77 |
| 350.43 | 5.16 | 5.16 |
| 399.50 | 6.92 | 6.92 |
| 400.49 | 6.31 | 6.31 |