Basic Information
ID: ALA2150038
Type: Binding
Description: Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISA
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA2150038
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 674.72 | 8.25 | 8.25 |
| 584.60 | 6.33 | 6.33 |
| 570.57 | 6.07 | 6.07 |
| 690.70 | 8.44 | 8.44 |
| 636.73 | 7.73 | 7.73 |
| 664.78 | 8.55 | 8.55 |
| 678.81 | 8.72 | 8.72 |
| 680.78 | 8.21 | 8.21 |
| 694.81 | 7.69 | 7.69 |
| 708.79 | 7.79 | 7.79 |
| 680.78 | 7.35 | 7.35 |
| 694.76 | 7.44 | 7.44 |
| 570.69 | 6.67 | 6.67 |
| 664.78 | 8.38 | 8.38 |
| 638.70 | 7.13 | 7.13 |
| 696.78 | 7.18 | 7.18 |
| 710.76 | 7.27 | 7.27 |
| 572.67 | 6.16 | 6.16 |
| 666.75 | 7.87 | 7.87 |