Basic Information
ID: ALA2155421
Type: ADME
Description: Intrinsic clearance in rat liver microsomes preincubated for 5 mins before addition of NADPH measured after 30 mins by LC/MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2155421
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.50 | 5.00 | 5.00 |
| 461.47 | 4.91 | 4.91 |
| 381.48 | 4.94 | 4.94 |
| 395.51 | 5.24 | 5.24 |
| 415.92 | 5.59 | 5.59 |
| 467.47 | 6.09 | 6.09 |
| 433.91 | 5.73 | 5.73 |
| 467.47 | 6.09 | 6.09 |
| 409.53 | 5.50 | 5.50 |
| 463.50 | 6.52 | 6.52 |
| 429.95 | 6.15 | 6.15 |
| 411.51 | 4.94 | 4.94 |
| 465.48 | 5.83 | 5.83 |
| 425.49 | 4.63 | 4.63 |
| 411.51 | 4.43 | 4.43 |
| 424.50 | 4.03 | 4.03 |
| 459.57 | 4.34 | 4.34 |
| 406.49 | 4.81 | 4.81 |
| 415.50 | 5.89 | 5.89 |
| 481.96 | 6.62 | 6.62 |
| 515.51 | 6.98 | 6.98 |
| 529.54 | 7.54 | 7.54 |
| 543.56 | 7.72 | 7.72 |
| 599.51 | 7.19 | 7.19 |
| 530.53 | 6.44 | 6.44 |
| 557.59 | 8.28 | 8.28 |
| 565.52 | 8.09 | 8.09 |
| 545.54 | 7.03 | 7.03 |
| 613.53 | 7.75 | 7.75 |
| 469.44 | 4.88 | 4.88 |
| 457.43 | 4.61 | 4.61 |
| 406.87 | 4.58 | 4.58 |
| 424.86 | 4.72 | 4.72 |
| 458.42 | 5.08 | 5.08 |
| 422.94 | 5.05 | 5.05 |
| 422.94 | 5.05 | 5.05 |
| 459.40 | 4.48 | 4.48 |
| 475.47 | 4.95 | 4.95 |
| 426.91 | 6.18 | 6.18 |
| 444.90 | 6.31 | 6.31 |
| 460.46 | 6.54 | 6.54 |
| 442.98 | 6.64 | 6.64 |
| 443.91 | 6.05 | 6.05 |
| 398.39 | 5.26 | 5.26 |
| 414.39 | 5.14 | 5.14 |
| 364.84 | 4.90 | 4.90 |
| 466.38 | 6.28 | 6.28 |
| 448.83 | 5.80 | 5.80 |
| 432.83 | 5.92 | 5.92 |
| 416.38 | 5.40 | 5.40 |
| 432.38 | 5.28 | 5.28 |