Assay Report Card

Basic Information

ID: ALA2155422

Type: Functional

Description: Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at 10 uM by FLIPR assay

Organism: Homo sapiens

Cell type: CHO-K1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
461.474.914.91
453.545.115.11
425.494.634.63
411.514.434.43
424.504.034.03
459.574.344.34
406.494.814.81
438.534.894.89
439.524.564.56
415.505.895.89