Basic Information
ID: ALA2155424
Type: Functional
Description: Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: 2-oxoglutarate receptor 1(ALA2150840)
Document: ALA2150920
Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2155424
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 395.51 | 5.24 | 5.24 |
| 415.92 | 5.59 | 5.59 |
| 429.95 | 6.15 | 6.15 |
| 529.54 | 7.54 | 7.54 |
| 458.42 | 5.08 | 5.08 |
| 426.91 | 6.18 | 6.18 |
| 448.83 | 5.80 | 5.80 |
| 432.83 | 5.92 | 5.92 |