Assay Report Card

Basic Information

ID: ALA2160291

Type: Functional

Description: Antagonist activity at XIAP linker BIR2-BIR3 domain assessed as induction of caspase-3 activity using Ac-DEVD-AFC as substrate preincubated for 15 mins measured after 1 hr by luminescence analysis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
477.611.341.34
519.651.601.60
1121.45
1037.28
1065.33
1093.38
1121.44
1149.49
1197.54
1137.44
1085.32