Basic Information
ID: ALA2160415
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes at 10 uM after 20 mins by LC-MS/MS analysis relative to control
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 2D6(ALA289)
Document: ALA2157870
Inhibition of CYP2D6 in human liver microsomes at 10 uM after 20 mins by LC-MS/MS analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2160415
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 341.45 | 3.24 | 3.24 |
| 534.70 | 5.65 | 5.65 |
| 443.59 | 5.12 | 5.12 |
| 552.69 | 5.79 | 5.79 |
| 552.69 | 5.79 | 5.79 |
| 461.58 | 5.26 | 5.26 |
| 458.60 | 4.37 | 4.37 |