Basic Information
ID: ALA2160579
Type: Binding
Description: Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry
Organism: Homo sapiens
Cell type: HEK-MT2
Activity Charts
Bioactivity
Activity Types for Assay ALA2160579
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 616.50 | -0.15 | -0.15 |
| 630.52 | 0.24 | 0.24 |
| 644.55 | 0.63 | 0.63 |
| 706.62 | 1.46 | 1.46 |
| 706.62 | 1.46 | 1.46 |
| 736.65 | 1.43 | 1.43 |
| 736.65 | 1.43 | 1.43 |
| 706.62 | 1.46 | 1.46 |
| 706.62 | 1.46 | 1.46 |
| 736.65 | 1.43 | 1.43 |
| 736.65 | 1.43 | 1.43 |
| 496.47 | 2.04 | 2.04 |
| 496.47 | 2.04 | 2.04 |
| 546.52 | 1.84 | 1.84 |
| 546.52 | 1.84 | 1.84 |
| 560.55 | 2.23 | 2.23 |
| 560.55 | 2.23 | 2.23 |
| 574.58 | 2.62 | 2.62 |
| 574.58 | 2.62 | 2.62 |
| 546.52 | 1.84 | 1.84 |
| 546.52 | 1.84 | 1.84 |
| 560.55 | 2.23 | 2.23 |
| 560.55 | 2.23 | 2.23 |
| 574.58 | 2.62 | 2.62 |
| 574.58 | 2.62 | 2.62 |
| 490.42 | 0.59 | 0.59 |
| 490.42 | 0.59 | 0.59 |
| 504.44 | 0.98 | 0.98 |
| 504.44 | 0.98 | 0.98 |
| 518.47 | 1.37 | 1.37 |
| 518.47 | 1.37 | 1.37 |
| 490.42 | 0.59 | 0.59 |
| 490.42 | 0.59 | 0.59 |
| 504.44 | 0.98 | 0.98 |
| 504.44 | 0.98 | 0.98 |
| 518.47 | 1.37 | 1.37 |
| 518.47 | 1.37 | 1.37 |
| 616.50 | -0.15 | -0.15 |
| 630.52 | 0.24 | 0.24 |
| 644.55 | 0.63 | 0.63 |
| 311.79 | 1.77 | 1.77 |
| 341.82 | 1.78 | 1.78 |
| 341.82 | 1.78 | 1.78 |
| 371.85 | 1.79 | 1.79 |
| 325.82 | 1.45 | 1.45 |
| 355.85 | 1.46 | 1.46 |
| 355.85 | 1.46 | 1.46 |
| 385.87 | 1.47 | 1.47 |
| 311.79 | 1.77 | 1.77 |
| 341.82 | 1.78 | 1.78 |
| 341.82 | 1.78 | 1.78 |
| 371.85 | 1.79 | 1.79 |
| 325.82 | 1.45 | 1.45 |
| 355.85 | 1.46 | 1.46 |
| 355.85 | 1.46 | 1.46 |
| 385.87 | 1.47 | 1.47 |
| 428.90 | 0.90 | 0.90 |
| 442.93 | 1.29 | 1.29 |
| 442.93 | 0.58 | 0.58 |
| 456.95 | 1.69 | 1.69 |
| 456.95 | 0.97 | 0.97 |
| 470.98 | 1.36 | 1.36 |
| 428.90 | 0.90 | 0.90 |
| 442.93 | 1.29 | 1.29 |
| 442.93 | 0.58 | 0.58 |
| 456.95 | 1.69 | 1.69 |
| 456.95 | 0.97 | 0.97 |
| 470.98 | 1.36 | 1.36 |
| 446.41 | 0.89 | 0.89 |
| 496.47 | 2.04 | 2.04 |
| 452.46 | 0.70 | 0.70 |
| 412.39 | -0.23 | -0.23 |
| 506.46 | 0.90 | 0.90 |