Basic Information
ID: ALA2160603
Type: Functional
Description: Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior to glucagon challenge measured after 30 mins post glucagon challenge by liquid scintillation counter
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Gastric inhibitory polypeptide receptor(ALA4383)
Document: ALA2157898
Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior to glucagon challenge measured after 30 mins post glucagon challenge by liquid scintillation counter: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2160603
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.37 | 6.68 | 6.68 |
| 588.49 | 7.50 | 7.50 |
| 586.90 | 7.22 | 7.22 |
| 544.44 | 6.93 | 6.93 |
| 628.43 | 7.83 | 7.83 |
| 628.43 | 7.83 | 7.83 |
| 600.93 | 7.78 | 7.78 |
| 642.46 | 8.39 | 8.39 |
| 642.46 | 8.39 | 8.39 |
| 626.46 | 8.51 | 8.51 |
| 592.91 | 8.14 | 8.14 |
| 572.49 | 7.80 | 7.80 |
| 600.55 | 8.61 | 8.61 |
| 602.52 | 7.89 | 7.89 |
| 588.49 | 7.50 | 7.50 |
| 588.49 | 7.50 | 7.50 |
| 622.04 | 7.86 | 7.86 |
| 584.07 | 6.85 | 6.85 |
| 612.13 | 7.63 | 7.63 |
| 601.63 | 7.52 | 7.52 |
| 605.59 | 7.35 | 7.35 |