Basic Information
ID: ALA2160805
Type: Functional
Description: Antagonist activity at human VPAC2 expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior to glucagon challenge measured after 30 mins post glucagon challenge by liquid scintillation counter
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Vasoactive intestinal polypeptide receptor 2(ALA4532)
Document: ALA2157898
Antagonist activity at human VPAC2 expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior to glucagon challenge measured after 30 mins post glucagon challenge by liquid scintillation counter: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2160805
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.49 | 7.50 | 7.50 |
| 588.49 | 7.50 | 7.50 |
| 588.49 | 7.50 | 7.50 |
| 622.04 | 7.86 | 7.86 |