Basic Information
ID: ALA2161253
Type: Functional
Description: Antagonist activity at Smo in mouse TM3 cells expressing Hh12 assessed as inhibition of 1 nM Ag1.5-induced Gli expression incubated for 30 mins prior to Ag1.5-induction measured after 48 hrs by luciferase reporter gene assay
Organism: Mus musculus
Cell type: TM3
Activity Charts
Bioactivity
Activity Types for Assay ALA2161253
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.93 | 5.22 | 5.22 |
| 497.00 | 6.31 | 6.31 |
| 511.03 | 6.70 | 6.70 |
| 511.03 | 6.70 | 6.70 |
| 510.04 | 7.30 | 7.30 |
| 510.04 | 7.30 | 7.30 |
| 510.04 | 7.30 | 7.30 |
| 530.05 | 5.92 | 5.92 |
| 496.01 | 6.91 | 6.91 |
| 396.88 | 6.69 | 6.69 |
| 480.02 | 7.68 | 7.68 |
| 481.99 | 6.53 | 6.53 |
| 438.53 | 5.14 | 5.14 |
| 413.48 | 5.32 | 5.32 |