Basic Information
ID: ALA2161530
Type: Functional
Description: Antagonist activity at APJ receptor expressed in CHOK1 cells assessed as inhibition of apelin13-induced beta-arrestin recruitment after 90 mins by luminescence assay
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA2161530
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.49 | 2.19 | 2.19 |
| 433.83 | 3.81 | 3.81 |
| 344.35 | 2.84 | 2.84 |
| 433.83 | 3.81 | 3.81 |
| 354.39 | 3.25 | 3.25 |
| 385.36 | 2.85 | 2.85 |
| 487.56 | 3.03 | 3.03 |
| 396.47 | 4.24 | 4.24 |
| 358.35 | 3.08 | 3.08 |
| 473.53 | 2.73 | 2.73 |
| 368.41 | 3.56 | 3.56 |
| 419.80 | 3.50 | 3.50 |
| 419.80 | 3.50 | 3.50 |
| 399.38 | 3.16 | 3.16 |
| 416.46 | 4.61 | 4.61 |
| 475.55 | 2.97 | 2.97 |
| 487.56 | 3.12 | 3.12 |
| 489.53 | 1.96 | 1.96 |
| 445.41 | 2.87 | 2.87 |
| 413.41 | 3.47 | 3.47 |
| 399.38 | 3.16 | 3.16 |
| 388.83 | 3.90 | 3.90 |
| 399.38 | 3.16 | 3.16 |
| 379.40 | 3.12 | 3.12 |
| 422.38 | 4.27 | 4.27 |
| 368.41 | 3.56 | 3.56 |
| 384.41 | 3.26 | 3.26 |
| 372.38 | 3.39 | 3.39 |
| 433.83 | 3.81 | 3.81 |
| 388.83 | 3.90 | 3.90 |
| 384.41 | 3.26 | 3.26 |
| 368.41 | 3.56 | 3.56 |
| 388.83 | 3.90 | 3.90 |
| 368.41 | 3.56 | 3.56 |
| 438.38 | 4.15 | 4.15 |
| 379.40 | 3.12 | 3.12 |
| 234.28 | 2.64 | 2.64 |
| 252.27 | 2.78 | 2.78 |
| 236.25 | 1.43 | 1.43 |
| 250.28 | 1.74 | 1.74 |
| 264.31 | 2.04 | 2.04 |
| 447.85 | 4.72 | 4.72 |
| 501.82 | 5.61 | 5.61 |
| 452.27 | 5.37 | 5.37 |
| 431.85 | 5.02 | 5.02 |
| 417.83 | 4.71 | 4.71 |
| 340.40 | 3.61 | 3.61 |
| 419.85 | 4.17 | 4.17 |
| 334.40 | 2.98 | 2.98 |
| 320.37 | 2.59 | 2.59 |
| 292.32 | 1.96 | 1.96 |
| 404.47 | 3.11 | 3.11 |
| 449.47 | 3.01 | 3.01 |
| 353.40 | 3.28 | 3.28 |
| 398.40 | 3.19 | 3.19 |
| 360.42 | 3.31 | 3.31 |
| 389.35 | 2.75 | 2.75 |
| 345.34 | 2.24 | 2.24 |
| 465.83 | 2.49 | 2.49 |
| 340.36 | 2.94 | 2.94 |
| 419.80 | 3.50 | 3.50 |
| 399.38 | 3.16 | 3.16 |
| 374.81 | 3.59 | 3.59 |
| 385.36 | 2.85 | 2.85 |
| 365.37 | 2.81 | 2.81 |
| 408.36 | 3.96 | 3.96 |
| 419.26 | 3.70 | 3.70 |
| 354.39 | 3.25 | 3.25 |
| 370.39 | 2.95 | 2.95 |
| 384.41 | 3.34 | 3.34 |
| 398.44 | 3.73 | 3.73 |
| 412.47 | 4.12 | 4.12 |