Basic Information
ID: ALA2161792
Type: Functional
Description: Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP response element (MRE/CRE)-driven reporter gene assay relative to 10 nM GLP1
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Glucagon-like peptide 1 receptor(ALA5862)
Document: ALA2157924
Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP response element (MRE/CRE)-driven reporter gene assay relative to 10 nM GLP1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2161792
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1181.35 | ||
| 1045.02 | ||
| 1105.21 | ||
| 1093.15 | ||
| 1077.19 | ||
| 961.03 | 6.69 | 6.69 |
| 880.90 | 5.13 | 5.13 |
| 824.88 | 6.79 | 6.79 |
| 764.83 | 6.77 | 6.77 |
| 824.88 | 6.79 | 6.79 |
| 880.99 | 8.35 | 8.35 |
| 977.08 | 9.93 | 9.93 |
| 977.08 | 9.93 | 9.93 |
| 1037.13 | ||
| 1033.19 | ||
| 1073.11 | ||
| 1093.24 | ||
| 938.99 | 6.70 | 6.70 |
| 878.94 | 6.69 | 6.69 |
| 1017.10 | ||
| 1105.21 | ||
| 1005.05 | ||
| 940.96 | 6.64 | 6.64 |
| 969.01 | 7.42 | 7.42 |
| 997.06 | 8.20 | 8.20 |
| 997.06 | 7.91 | 7.91 |
| 4169.54 | ||
| 1077.16 | ||
| 1077.16 | ||
| 1077.16 | ||
| 1077.16 | ||
| 552.61 | 5.06 | 5.06 |
| 1075.19 | ||
| 1105.21 | ||
| 1069.18 | ||
| 1013.07 | ||
| 1041.13 | ||
| 1097.23 | ||
| 961.00 | 6.57 | 6.57 |
| 989.05 | 7.35 | 7.35 |
| 1017.10 | ||
| 1017.10 | ||
| 1045.16 | ||
| 1201.39 | ||
| 1173.24 | ||
| 1029.89 | ||
| 1113.19 | ||
| 1023.16 | ||
| 1247.42 | ||
| 1151.15 | ||
| 1135.15 | ||
| 1219.31 | ||
| 1019.08 | ||
| 992.99 | 4.51 | 4.51 |