Basic Information
ID: ALA2161885
Type: Binding
Description: Inhibition of Trypanosoma brucei MetRS aminoacylation activity assessed as reduction in [3H]methionine incorporation into Escherichia coli tRNA pre-incubated for 15 mins before tRNA addition and measured after 120 mins by scintillation counting
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA2161885
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 352.26 | 4.29 | 4.29 |
| 347.85 | 3.65 | 3.65 |
| 368.26 | 4.00 | 4.00 |
| 368.26 | 4.00 | 4.00 |
| 370.25 | 4.43 | 4.43 |
| 358.29 | 4.36 | 4.36 |
| 353.88 | 3.71 | 3.71 |
| 358.29 | 4.36 | 4.36 |