Basic Information
ID: ALA2162286
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as glutathione-compound covalent adduct formation at 50 uM preincubated for 5 mins measured after 30 mins by UPLC/UV/MS analysis relative to parent compound
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Liver microsomes(ALA613373)
Document: ALA2157957
Drug metabolism in human liver microsomes assessed as glutathione-compound covalent adduct formation at 50 uM preincubated for 5 mins measured after 30 mins by UPLC/UV/MS analysis relative to parent compound: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2162286
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 565.70 | 3.05 | 3.05 |
| 486.58 | 3.82 | 3.82 |
| 577.71 | 3.52 | 3.52 |
| 598.13 | 3.86 | 3.86 |
| 583.69 | 3.19 | 3.19 |
| 583.69 | 3.19 | 3.19 |
| 571.65 | 3.32 | 3.32 |
| 521.65 | 3.30 | 3.30 |
| 444.54 | 3.91 | 3.91 |
| 503.60 | 3.69 | 3.69 |