Basic Information
ID: ALA2162521
Type: Binding
Description: Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptake
Organism: Homo sapiens
Cell type: COS-7
Activity Charts
Bioactivity
Activity Types for Assay ALA2162521
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 482.53 | 1.64 | 1.64 |
| 498.58 | 2.06 | 2.06 |
| 484.55 | 1.88 | 1.88 |
| 470.52 | 1.32 | 1.32 |
| 456.50 | 1.07 | 1.07 |
| 510.47 | 1.78 | 1.78 |
| 510.47 | 1.78 | 1.78 |
| 404.34 | 0.20 | 0.20 |
| 420.34 | -0.10 | -0.10 |
| 420.34 | -0.10 | -0.10 |
| 420.34 | -0.10 | -0.10 |
| 510.47 | 1.78 | 1.78 |
| 408.45 | 0.32 | 0.32 |
| 406.48 | 0.92 | 0.92 |
| 394.42 | 0.01 | 0.01 |
| 392.45 | 0.61 | 0.61 |
| 403.44 | 0.17 | 0.17 |
| 394.42 | 0.01 | 0.01 |
| 408.45 | 0.31 | 0.31 |
| 406.48 | 0.86 | 0.86 |
| 392.45 | 0.61 | 0.61 |
| 396.42 | 0.44 | 0.44 |
| 403.44 | 0.17 | 0.17 |
| 394.42 | 0.01 | 0.01 |
| 408.45 | 0.31 | 0.31 |
| 406.48 | 0.86 | 0.86 |
| 446.42 | 1.32 | 1.32 |
| 392.45 | 0.61 | 0.61 |
| 396.42 | 0.44 | 0.44 |
| 378.43 | 0.30 | 0.30 |