Basic Information
ID: ALA2166382
Type: Binding
Description: Displacement of [I125]ET1 from recombinant ETA receptor expressed in CHO cells after 2 hrs by TopCount analysis
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2166382
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 551.63 | 4.20 | 4.20 |
| 610.71 | 0.83 | 0.83 |
| 614.52 | 4.53 | 4.53 |
| 588.28 | 3.57 | 3.57 |
| 650.35 | 4.71 | 4.71 |
| 616.29 | 2.91 | 2.91 |
| 543.83 | 3.46 | 3.46 |
| 555.41 | 2.94 | 2.94 |
| 589.86 | 3.60 | 3.60 |
| 573.27 | 4.07 | 4.07 |
| 587.29 | 4.46 | 4.46 |
| 523.57 | 3.09 | 3.09 |
| 433.45 | 1.48 | 1.48 |
| 629.70 | 5.08 | 5.08 |
| 601.65 | 3.97 | 3.97 |
| 511.52 | 2.35 | 2.35 |
| 615.67 | 4.28 | 4.28 |
| 636.09 | 4.62 | 4.62 |
| 680.54 | 4.73 | 4.73 |
| 631.67 | 3.98 | 3.98 |
| 647.74 | 4.69 | 4.69 |
| 669.64 | 4.99 | 4.99 |
| 641.71 | 4.84 | 4.84 |
| 661.70 | 3.98 | 3.98 |
| 708.60 | 5.84 | 5.84 |
| 652.49 | 4.55 | 4.55 |
| 666.51 | 4.69 | 4.69 |
| 694.57 | 5.12 | 5.12 |
| 590.42 | 3.12 | 3.12 |
| 604.44 | 3.51 | 3.51 |
| 618.47 | 3.90 | 3.90 |
| 632.50 | 4.29 | 4.29 |
| 681.53 | 4.19 | 4.19 |
| 605.43 | 2.62 | 2.62 |
| 619.46 | 3.01 | 3.01 |
| 633.49 | 3.40 | 3.40 |
| 647.51 | 3.79 | 3.79 |
| 695.56 | 4.53 | 4.53 |
| 661.49 | 2.73 | 2.73 |
| 681.53 | 4.19 | 4.19 |
| 680.54 | 4.80 | 4.80 |
| 688.56 | 3.57 | 3.57 |
| 643.52 | 4.61 | 4.61 |
| 633.48 | 3.74 | 3.74 |
| 677.53 | 3.76 | 3.76 |
| 546.20 | 2.53 | 2.53 |
| 2515.80 | ||
| 603.46 | 3.73 | 3.73 |
| 603.46 | 3.73 | 3.73 |
| 637.90 | 4.39 | 4.39 |
| 557.43 | 3.60 | 3.60 |
| 571.46 | 3.91 | 3.91 |
| 591.88 | 4.25 | 4.25 |
| 636.33 | 4.36 | 4.36 |
| 585.48 | 4.16 | 4.16 |
| 599.51 | 4.72 | 4.72 |
| 560.23 | 2.79 | 2.79 |
| 574.26 | 3.18 | 3.18 |
| 602.31 | 3.96 | 3.96 |
| 586.27 | 3.33 | 3.33 |