Assay Report Card

Basic Information

ID: ALA2168434

Type: Functional

Description: Agonist activity at glucosylceramidase N444P mutant in lymphoblast obtained from gauchers patient using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated at 1 to 5000 nM for 3 days measured 2 hrs post substrate addition by fluorescence assay relative to untreated control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
289.420.500.50
341.88-0.49-0.49
341.88-0.49-0.49
468.122.982.98