Basic Information
ID: ALA2168708
Type: Binding
Description: Inhibition of human recombinant CatK assessed as suppression of enzyme-mediated Z-Phe-Arg-AMC cleavage incubated for 1 hrs by QFRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2168708
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.55 | 2.29 | 2.29 |
| 525.57 | 4.63 | 4.63 |
| 468.58 | 2.43 | 2.43 |
| 468.58 | 2.43 | 2.43 |
| 424.93 | 3.68 | 3.68 |
| 404.51 | 3.34 | 3.34 |
| 469.38 | 3.79 | 3.79 |
| 415.50 | 2.90 | 2.90 |
| 458.48 | 4.05 | 4.05 |
| 420.51 | 3.04 | 3.04 |
| 436.58 | 3.75 | 3.75 |
| 474.48 | 3.93 | 3.93 |
| 434.54 | 3.43 | 3.43 |
| 468.58 | 2.43 | 2.43 |
| 391.47 | 3.30 | 3.30 |
| 448.54 | 3.66 | 3.66 |
| 492.60 | 3.67 | 3.67 |
| 391.48 | 2.43 | 2.43 |
| 237.30 | 0.52 | 0.52 |
| 277.37 | 1.45 | 1.45 |
| 275.35 | 1.22 | 1.22 |
| 325.41 | 2.02 | 2.02 |
| 292.38 | 0.21 | 0.21 |
| 354.45 | 1.78 | 1.78 |
| 382.44 | 2.64 | 2.64 |
| 408.48 | 3.17 | 3.17 |
| 396.47 | 3.03 | 3.03 |
| 396.47 | 3.03 | 3.03 |
| 438.55 | 4.05 | 4.05 |
| 390.49 | 3.03 | 3.03 |
| 408.48 | 3.17 | 3.17 |
| 408.48 | 3.17 | 3.17 |
| 408.48 | 3.17 | 3.17 |
| 440.49 | 3.32 | 3.32 |
| 424.93 | 3.68 | 3.68 |
| 420.51 | 3.04 | 3.04 |
| 458.48 | 4.05 | 4.05 |
| 432.57 | 4.15 | 4.15 |