Basic Information
ID: ALA2172826
Type: Binding
Description: Inhibition of glucocerebrosidase N370S mutant in Gaucher patient spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured after 20 mins by fluorimetric analysis
Organism: Homo sapiens
Tissue: Spleen
Activity Charts
Bioactivity
Activity Types for Assay ALA2172826
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 556.36 | 5.37 | 5.37 |
| 364.84 | 2.28 | 2.28 |
| 388.47 | 3.15 | 3.15 |
| 486.62 | 5.02 | 5.02 |