ID: ALA2172850
Type: Binding
Description: Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 mins by RP-HPLC analysis
Organism: Homo sapiens
Cell type: A549
Subcellular Fraction: Microsome
Bioactivity
Activity Types for Assay ALA2172850
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
472.09 | 8.01 | 8.01 |
283.33 | 3.73 | 3.73 |
410.50 | 3.90 | 3.90 |
466.60 | 5.46 | 5.46 |
602.60 | 7.49 | 7.49 |
634.60 | 7.25 | 7.25 |
556.60 | 5.27 | 5.27 |
516.62 | 5.20 | 5.20 |
478.66 | 5.58 | 5.58 |
506.75 | 7.69 | 7.69 |
478.70 | 6.91 | 6.91 |
450.65 | 6.13 | 6.13 |
394.54 | 4.57 | 4.57 |
398.57 | 5.06 | 5.06 |
494.66 | 6.24 | 6.24 |
486.59 | 5.64 | 5.64 |
522.71 | 7.02 | 7.02 |
494.66 | 6.24 | 6.24 |
438.55 | 5.37 | 5.37 |
526.66 | 5.47 | 5.47 |
438.55 | 4.67 | 4.67 |
494.66 | 6.07 | 6.07 |
446.59 | 6.36 | 6.36 |
444.57 | 6.59 | 6.59 |
464.63 | 6.67 | 6.67 |
448.56 | 5.95 | 5.95 |
446.59 | 6.36 | 6.36 |
446.59 | 6.36 | 6.36 |
446.59 | 6.36 | 6.36 |
446.59 | 6.36 | 6.36 |
444.57 | 6.59 | 6.59 |
456.67 | 8.04 | 8.04 |
580.57 | 8.63 | 8.63 |
552.51 | 8.54 | 8.54 |
504.59 | 8.29 | 8.29 |
444.57 | 6.59 | 6.59 |